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Protein

Signal recognition particle receptor FtsY

Gene

ftsY

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi99 – 106GTPUniRule annotation8
Nucleotide bindingi181 – 185GTPUniRule annotation5
Nucleotide bindingi245 – 248GTPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Cell cycle, Cell divisionImported

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Signal recognition particle receptor FtsYUniRule annotation
Short name:
SRP receptorUniRule annotation
Gene namesi
Name:ftsYUniRule annotation
Ordered Locus Names:TM_0570Imported
ORF Names:Tmari_0568Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000013901 Componenti: Chromosome
  • UP000008183 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, CytoplasmUniRule annotation, Membrane

Interactioni

Subunit structurei

Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.UniRule annotation

Protein-protein interaction databases

STRINGi243274.TM0570.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1VMAX-ray1.60A/B1-294[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini266 – 279SRP54InterPro annotationAdd BLAST14

Sequence similaritiesi

Belongs to the GTP-binding SRP family. FtsY subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCP. Bacteria.
COG0552. LUCA.
KOiK03110.
OMAiGCDIIKH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00920. FtsY. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR013822. Signal_recog_particl_SRP54_hlx.
IPR004390. SR_rcpt_FtsY.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PfamiPF00448. SRP54. 1 hit.
PF02881. SRP54_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
SM00963. SRP54_N. 1 hit.
[Graphical view]
SUPFAMiSSF47364. SSF47364. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00064. ftsY. 1 hit.
PROSITEiPS00300. SRP54. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9WZ40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLFDFLKKG LQKTKETFFG RVVKLLKGKK LDDETREELE ELLIQADVGV
60 70 80 90 100
ETTEYILERL EEKDGDALES LKEIILEILN FDTKLNVPPE PPFVIMVVGV
110 120 130 140 150
NGTGKTTSCG KLAKMFVDEG KSVVLAAADT FRAAAIEQLK IWGERVGATV
160 170 180 190 200
ISHSEGADPA AVAFDAVAHA LARNKDVVII DTAGRLHTKK NLMEELRKVH
210 220 230 240 250
RVVKKKIPDA PHETLLVIDA TTGQNGLVQA KIFKEAVNVT GIILTKLDGT
260 270 280 290
AKGGITLAIA RELGIPIKFI GVGEKAEDLR PFDPEAFVEV LLSE
Length:294
Mass (Da):32,046
Last modified:November 1, 1999 - v1
Checksum:i54D54E0B1F18A833
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35655.1.
CP004077 Genomic DNA. Translation: AGL49493.1.
PIRiA72362.
RefSeqiNP_228380.1. NC_000853.1.
WP_004081293.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD35655; AAD35655; TM_0570.
AGL49493; AGL49493; Tmari_0568.
GeneIDi897634.
KEGGitma:TM0570.
tmi:THEMA_01820.
tmm:Tmari_0568.
tmw:THMA_0584.
PATRICi23936049. VBITheMar51294_0579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35655.1.
CP004077 Genomic DNA. Translation: AGL49493.1.
PIRiA72362.
RefSeqiNP_228380.1. NC_000853.1.
WP_004081293.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1VMAX-ray1.60A/B1-294[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM0570.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD35655; AAD35655; TM_0570.
AGL49493; AGL49493; Tmari_0568.
GeneIDi897634.
KEGGitma:TM0570.
tmi:THEMA_01820.
tmm:Tmari_0568.
tmw:THMA_0584.
PATRICi23936049. VBITheMar51294_0579.

Phylogenomic databases

eggNOGiENOG4105CCP. Bacteria.
COG0552. LUCA.
KOiK03110.
OMAiGCDIIKH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00920. FtsY. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR013822. Signal_recog_particl_SRP54_hlx.
IPR004390. SR_rcpt_FtsY.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PfamiPF00448. SRP54. 1 hit.
PF02881. SRP54_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
SM00963. SRP54_N. 1 hit.
[Graphical view]
SUPFAMiSSF47364. SSF47364. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00064. ftsY. 1 hit.
PROSITEiPS00300. SRP54. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9WZ40_THEMA
AccessioniPrimary (citable) accession number: Q9WZ40
Secondary accession number(s): G4FDQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: November 2, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.