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Q9WZ31

- CORA_THEMA

UniProt

Q9WZ31 - CORA_THEMA

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Protein

Magnesium transport protein CorA

Gene

corA

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Mediates influx of magnesium ions.By similarity

GO - Molecular functioni

  1. cobalt ion transmembrane transporter activity Source: InterPro
  2. magnesium ion transmembrane transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BRENDAi3.6.3.2. 6331.

Protein family/group databases

TCDBi1.A.35.3.2. the cora metal ion transporter (mit) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium transport protein CorA
Gene namesi
Name:corA
Ordered Locus Names:TM_0561
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
ProteomesiUP000008183: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351Magnesium transport protein CorAPRO_0000239049Add
BLAST

Interactioni

Subunit structurei

Homopentamer.2 Publications

Protein-protein interaction databases

DIPiDIP-59006N.
STRINGi243274.TM0561.

Structurei

Secondary structure

1
351
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi5 – 73
Beta strandi28 – 358
Beta strandi38 – 458
Helixi47 – 493
Helixi51 – 555
Beta strandi60 – 656
Helixi70 – 8011
Helixi84 – 918
Beta strandi98 – 1014
Beta strandi103 – 11412
Turni117 – 1204
Beta strandi123 – 13210
Beta strandi135 – 1439
Helixi148 – 1558
Helixi161 – 1633
Helixi166 – 19732
Helixi208 – 24235
Helixi244 – 27229
Helixi275 – 31036
Beta strandi311 – 3133
Helixi319 – 3224
Helixi326 – 34419
Turni345 – 3484

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2BBHX-ray1.85A1-266[»]
2BBJX-ray3.90A/B/D/E/F1-351[»]
2HN2X-ray3.70A/B/C/D/E1-351[»]
2IUBX-ray2.90A/B/C/D/E/F/G/H/I/J1-351[»]
4EEBX-ray3.80A/B/C/D/E26-351[»]
4EEDX-ray3.92A/B/C/D/E26-351[»]
4I0UX-ray2.70A/B/C/D/E/F/G/H/I/J1-351[»]
ProteinModelPortaliQ9WZ31.
SMRiQ9WZ31. Positions 5-349.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9WZ31.

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 292292CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini314 – 32411PeriplasmicSequence AnalysisAdd
BLAST
Topological domaini346 – 3516CytoplasmicSequence Analysis

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei293 – 31321HelicalSequence AnalysisAdd
BLAST
Transmembranei325 – 34521HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili178 – 22548Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi346 – 3494Poly-Lys

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0598.
InParanoidiQ9WZ31.
KOiK03284.
OMAiNTRQRPK.
OrthoDBiEOG6W9X5H.

Family and domain databases

InterProiIPR004488. Mg/Co-transport_prot_CorA.
IPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
[Graphical view]
PfamiPF01544. CorA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00383. corA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9WZ31-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEEKRLSAKK GLPPGTLVYT GKYREDFEIE VMNYSIEEFR EFKTTDVESV
60 70 80 90 100
LPFRDSSTPT WINITGIHRT DVVQRVGEFF GIHPLVLEDI LNVHQRPKVE
110 120 130 140 150
FFENYVFIVL KMFTYDKNLH ELESEQVSLI LTKNCVLMFQ EKIGDVFDPV
160 170 180 190 200
RERIRYNRGI IRKKRADYLL YSLIDALVDD YFVLLEKIDD EIDVLEEEVL
210 220 230 240 250
ERPEKETVQR THQLKRNLVE LRKTIWPLRE VLSSLYRDVP PLIEKETVPY
260 270 280 290 300
FRDVYDHTIQ IADTVETFRD IVSGLLDVYL SSVSNKTNEV MKVLTIIATI
310 320 330 340 350
FMPLTFIAGI YGMNFEYMPE LRWKWGYPVV LAVMGVIAVI MVVYFKKKKW

L
Length:351
Mass (Da):41,446
Last modified:November 1, 1999 - v1
Checksum:i6A845EC612A4A0BA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000512 Genomic DNA. Translation: AAD35646.1.
PIRiH72360.
RefSeqiNP_228371.1. NC_000853.1.
YP_007976908.1. NC_021214.1.
YP_008990470.1. NC_023151.1.

Genome annotation databases

EnsemblBacteriaiAAD35646; AAD35646; TM_0561.
GeneIDi18092230.
897621.
KEGGitma:TM0561.
tmi:THEMA_01870.
tmm:Tmari_0558.
PATRICi23936029. VBITheMar51294_0569.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000512 Genomic DNA. Translation: AAD35646.1 .
PIRi H72360.
RefSeqi NP_228371.1. NC_000853.1.
YP_007976908.1. NC_021214.1.
YP_008990470.1. NC_023151.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2BBH X-ray 1.85 A 1-266 [» ]
2BBJ X-ray 3.90 A/B/D/E/F 1-351 [» ]
2HN2 X-ray 3.70 A/B/C/D/E 1-351 [» ]
2IUB X-ray 2.90 A/B/C/D/E/F/G/H/I/J 1-351 [» ]
4EEB X-ray 3.80 A/B/C/D/E 26-351 [» ]
4EED X-ray 3.92 A/B/C/D/E 26-351 [» ]
4I0U X-ray 2.70 A/B/C/D/E/F/G/H/I/J 1-351 [» ]
ProteinModelPortali Q9WZ31.
SMRi Q9WZ31. Positions 5-349.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-59006N.
STRINGi 243274.TM0561.

Protein family/group databases

TCDBi 1.A.35.3.2. the cora metal ion transporter (mit) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD35646 ; AAD35646 ; TM_0561 .
GeneIDi 18092230.
897621.
KEGGi tma:TM0561.
tmi:THEMA_01870.
tmm:Tmari_0558.
PATRICi 23936029. VBITheMar51294_0569.

Phylogenomic databases

eggNOGi COG0598.
InParanoidi Q9WZ31.
KOi K03284.
OMAi NTRQRPK.
OrthoDBi EOG6W9X5H.

Enzyme and pathway databases

BRENDAi 3.6.3.2. 6331.

Miscellaneous databases

EvolutionaryTracei Q9WZ31.

Family and domain databases

InterProi IPR004488. Mg/Co-transport_prot_CorA.
IPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
[Graphical view ]
Pfami PF01544. CorA. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00383. corA. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS), SUBUNIT, TOPOLOGY.
  3. "Crystal structure of a divalent metal ion transporter CorA at 2.9 Angstrom resolution."
    Eshaghi S., Niegowski D., Kohl A., Molina D.M., Lesley S.A., Nordlund P.
    Science 313:354-357(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS), SUBUNIT, TOPOLOGY.

Entry informationi

Entry nameiCORA_THEMA
AccessioniPrimary (citable) accession number: Q9WZ31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3