Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9WZ31

- CORA_THEMA

UniProt

Q9WZ31 - CORA_THEMA

Protein

Magnesium transport protein CorA

Gene

corA

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Nov 1999)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Mediates influx of magnesium ions.By similarity

    GO - Molecular functioni

    1. cobalt ion transmembrane transporter activity Source: InterPro
    2. magnesium ion transmembrane transporter activity Source: InterPro

    Keywords - Biological processi

    Ion transport, Transport

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    BRENDAi3.6.3.2. 6331.

    Protein family/group databases

    TCDBi1.A.35.3.2. the cora metal ion transporter (mit) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Magnesium transport protein CorA
    Gene namesi
    Name:corA
    Ordered Locus Names:TM_0561
    OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    Taxonomic identifieri243274 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
    ProteomesiUP000008183: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 351351Magnesium transport protein CorAPRO_0000239049Add
    BLAST

    Interactioni

    Subunit structurei

    Homopentamer.2 Publications

    Protein-protein interaction databases

    DIPiDIP-59006N.
    STRINGi243274.TM0561.

    Structurei

    Secondary structure

    1
    351
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi5 – 73
    Beta strandi28 – 358
    Beta strandi38 – 458
    Helixi47 – 493
    Helixi51 – 555
    Beta strandi60 – 656
    Helixi70 – 8011
    Helixi84 – 918
    Beta strandi98 – 1014
    Beta strandi103 – 11412
    Turni117 – 1204
    Beta strandi123 – 13210
    Beta strandi135 – 1439
    Helixi148 – 1558
    Helixi161 – 1633
    Helixi166 – 19732
    Helixi208 – 24235
    Helixi244 – 27229
    Helixi275 – 31036
    Beta strandi311 – 3133
    Helixi319 – 3224
    Helixi326 – 34419
    Turni345 – 3484

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2BBHX-ray1.85A1-266[»]
    2BBJX-ray3.90A/B/D/E/F1-351[»]
    2HN2X-ray3.70A/B/C/D/E1-351[»]
    2IUBX-ray2.90A/B/C/D/E/F/G/H/I/J1-351[»]
    4EEBX-ray3.80A/B/C/D/E26-351[»]
    4EEDX-ray3.92A/B/C/D/E26-351[»]
    4I0UX-ray2.70A/B/C/D/E/F/G/H/I/J1-351[»]
    ProteinModelPortaliQ9WZ31.
    SMRiQ9WZ31. Positions 5-349.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ9WZ31.

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 292292CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini314 – 32411PeriplasmicSequence AnalysisAdd
    BLAST
    Topological domaini346 – 3516CytoplasmicSequence Analysis

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei293 – 31321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei325 – 34521HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili178 – 22548Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi346 – 3494Poly-Lys

    Sequence similaritiesi

    Keywords - Domaini

    Coiled coil, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0598.
    KOiK03284.
    OMAiNTRQRPK.
    OrthoDBiEOG6W9X5H.

    Family and domain databases

    InterProiIPR004488. Mg/Co-transport_prot_CorA.
    IPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
    [Graphical view]
    PfamiPF01544. CorA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00383. corA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9WZ31-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEEKRLSAKK GLPPGTLVYT GKYREDFEIE VMNYSIEEFR EFKTTDVESV    50
    LPFRDSSTPT WINITGIHRT DVVQRVGEFF GIHPLVLEDI LNVHQRPKVE 100
    FFENYVFIVL KMFTYDKNLH ELESEQVSLI LTKNCVLMFQ EKIGDVFDPV 150
    RERIRYNRGI IRKKRADYLL YSLIDALVDD YFVLLEKIDD EIDVLEEEVL 200
    ERPEKETVQR THQLKRNLVE LRKTIWPLRE VLSSLYRDVP PLIEKETVPY 250
    FRDVYDHTIQ IADTVETFRD IVSGLLDVYL SSVSNKTNEV MKVLTIIATI 300
    FMPLTFIAGI YGMNFEYMPE LRWKWGYPVV LAVMGVIAVI MVVYFKKKKW 350
    L 351
    Length:351
    Mass (Da):41,446
    Last modified:November 1, 1999 - v1
    Checksum:i6A845EC612A4A0BA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000512 Genomic DNA. Translation: AAD35646.1.
    PIRiH72360.
    RefSeqiNP_228371.1. NC_000853.1.
    WP_004081315.1. NC_023151.1.
    YP_007976908.1. NC_021214.1.
    YP_008990470.1. NC_023151.1.

    Genome annotation databases

    EnsemblBacteriaiAAD35646; AAD35646; TM_0561.
    GeneIDi897621.
    KEGGitma:TM0561.
    tmi:THEMA_01870.
    tmm:Tmari_0558.
    PATRICi23936029. VBITheMar51294_0569.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000512 Genomic DNA. Translation: AAD35646.1 .
    PIRi H72360.
    RefSeqi NP_228371.1. NC_000853.1.
    WP_004081315.1. NC_023151.1.
    YP_007976908.1. NC_021214.1.
    YP_008990470.1. NC_023151.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2BBH X-ray 1.85 A 1-266 [» ]
    2BBJ X-ray 3.90 A/B/D/E/F 1-351 [» ]
    2HN2 X-ray 3.70 A/B/C/D/E 1-351 [» ]
    2IUB X-ray 2.90 A/B/C/D/E/F/G/H/I/J 1-351 [» ]
    4EEB X-ray 3.80 A/B/C/D/E 26-351 [» ]
    4EED X-ray 3.92 A/B/C/D/E 26-351 [» ]
    4I0U X-ray 2.70 A/B/C/D/E/F/G/H/I/J 1-351 [» ]
    ProteinModelPortali Q9WZ31.
    SMRi Q9WZ31. Positions 5-349.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-59006N.
    STRINGi 243274.TM0561.

    Protein family/group databases

    TCDBi 1.A.35.3.2. the cora metal ion transporter (mit) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD35646 ; AAD35646 ; TM_0561 .
    GeneIDi 897621.
    KEGGi tma:TM0561.
    tmi:THEMA_01870.
    tmm:Tmari_0558.
    PATRICi 23936029. VBITheMar51294_0569.

    Phylogenomic databases

    eggNOGi COG0598.
    KOi K03284.
    OMAi NTRQRPK.
    OrthoDBi EOG6W9X5H.

    Enzyme and pathway databases

    BRENDAi 3.6.3.2. 6331.

    Miscellaneous databases

    EvolutionaryTracei Q9WZ31.

    Family and domain databases

    InterProi IPR004488. Mg/Co-transport_prot_CorA.
    IPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
    [Graphical view ]
    Pfami PF01544. CorA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00383. corA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
    2. Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS), SUBUNIT, TOPOLOGY.
    3. "Crystal structure of a divalent metal ion transporter CorA at 2.9 Angstrom resolution."
      Eshaghi S., Niegowski D., Kohl A., Molina D.M., Lesley S.A., Nordlund P.
      Science 313:354-357(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS), SUBUNIT, TOPOLOGY.

    Entry informationi

    Entry nameiCORA_THEMA
    AccessioniPrimary (citable) accession number: Q9WZ31
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2006
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3