Q9WYS8 (Q9WYS8_THEMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphoribosylaminoimidazole carboxylase, ATPase subunit EMBL AAD35542.1

Gene names

Ordered Locus Names:

TM_0447

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 ATP-grasp domain. SAAS SAAS003135

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS003135
Ligand	ATP-binding SAAS SAAS003135 Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9WYS8 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: EF7C976C5B212CB6	FASTA	380	42,560
	10 20 30 40 50 60 MKKIGIIGGG QLGKMMTLEA KKMGFYVIVL DPTPRSPAGQ VADEQIVAGF FDSERIEDLV 70 80 90 100 110 120 KGSDVTTYDL EHIDVQTLKK LYNEGYKIHP SPYTLEIIQD KFVQKEFLKK NGIPVPEYKL 130 140 150 160 170 180 VKDLESDVRE FGFPVVQKAR KGGYDGRGVF IIKNEKDLEN AIKGETYLEE FVEIEKELAV 190 200 210 220 230 240 MVARNEKGEI ACYPVVEMYF DEDANICDTV IAPARIEEKY SKIAREIATS VVEALEGVGI 250 260 270 280 290 300 FGIEMFLTKQ GEILVNEIAP RPHNSGHYTI EACVTSQFEQ HIRAIMNLPL GSTELLIPAV 310 320 330 340 350 360 MVNLLGEEGY YGKPALIGLE EALAIEGLSL HFYGKKETRP YRKMGHFTVV DRDVERALEK 370 380 ALRAKKILKV VSEEGAMCQG

References

[1]

"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000512 Genomic DNA. Translation: AAD35542.1.
PIR	H72374.
RefSeq	NP_228257.1. NC_000853.1.
3D structure databases
HSSP	HSSP built from PDB template 1B6R based on UniProtKB P09029.
ProteinModelPortal	Q9WYS8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	897466.
GenomeReviews	Gene locus TM_0447 in contig AE000512_GR.
KEGG	tma:TM0447.
NMPDR	fig|243274.1.peg.441.
PATRIC	23935779. VBITheMar51294_0453.
TIGR	TM_0447.
Phylogenomic databases
HOGENOM	HBG516369.
OMA	GRKMGHF.
PhylomeDB	Q9WYS8.
ProtClustDB	PRK06019.
Enzyme and pathway databases
BioCyc	TMAR243274:TM_0447-MONOMER.
Family and domain databases
InterPro	IPR006115. 6PGDH_NADP-bd. IPR005875. AIR_COase_ATPase-su. IPR011761. ATP-grasp. IPR003135. ATP-grasp_carboxylate-amine. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR013817. Pre-ATP_grasp. IPR016185. PreATP-grasp-like. IPR011054. Rudment_hybrid_motif. [Graphical view]
Gene3D	G3DSA:3.30.1490.20. ATP_grasp_subdomain_1. 1 hit. G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:3.40.50.20. Pre-ATP_grasp. 1 hit.
KO	K01589.
Pfam	PF02222. ATP-grasp. 1 hit. PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF52440. PreATP-grasp-like. 1 hit. SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMs	TIGR01161. PurK. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9WYS8_THEMA

Accession

Primary (citable) accession number: Q9WYS8

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	December 14, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)