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Protein
Submitted name:

Response regulator

Gene

TM_0399

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi10MagnesiumCombined sources1
Metal bindingi53MagnesiumCombined sources1
Metal bindingi55MagnesiumCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi126 – 224OmpR/PhoB-typePROSITE-ProRule annotationAdd BLAST99

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation, Two-component regulatory systemSAAS annotation
LigandMagnesiumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Response regulatorImported
Gene namesi
Ordered Locus Names:TM_0399Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0399.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KGSX-ray1.50A1-225[»]
3NNNX-ray2.20A/B1-122[»]
ProteinModelPortaliQ9WYN0.
SMRiQ9WYN0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9WYN0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 118Response regulatoryInterPro annotationAdd BLAST115
Domaini126 – 224OmpR/PhoB-type DNA-bindingInterPro annotationAdd BLAST99

Phylogenomic databases

eggNOGiENOG4105CK6. Bacteria.
COG0745. LUCA.
InParanoidiQ9WYN0.
OMAiDNHTTPV.

Family and domain databases

CDDicd00383. trans_reg_C. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR001867. OmpR/PhoB-type_DNA-bd.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS51755. OMPR_PHOB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9WYN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVRVLVVED ERDLADLITE ALKKEMFTVD VCYDGEEGMY MALNEPFDVV
60 70 80 90 100
ILDIMLPVHD GWEILKSMRE SGVNTPVLML TALSDVEYRV KGLNMGADDY
110 120 130 140 150
LPKPFDLREL IARVRALIRR KSESKSTKLV CGDLILDTAT KKAYRGSKEI
160 170 180 190 200
DLTKKEYQIL EYLVMNKNRV VTKEELQEHL WSFDDEVFSD VLRSHIKNLR
210 220
KKVDKGFKKK IIHTVRGIGY VARDE
Length:225
Mass (Da):26,015
Last modified:November 1, 1999 - v1
Checksum:i4CB1F2CC82A218F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35484.1.
PIRiH72382.
RefSeqiNP_228209.1. NC_000853.1.
WP_004083233.1. NC_000853.1.

Genome annotation databases

EnsemblBacteriaiAAD35484; AAD35484; TM_0399.
GeneIDi897392.
KEGGitma:TM0399.
PATRICi23935681. VBITheMar51294_0404.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35484.1.
PIRiH72382.
RefSeqiNP_228209.1. NC_000853.1.
WP_004083233.1. NC_000853.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KGSX-ray1.50A1-225[»]
3NNNX-ray2.20A/B1-122[»]
ProteinModelPortaliQ9WYN0.
SMRiQ9WYN0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM0399.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD35484; AAD35484; TM_0399.
GeneIDi897392.
KEGGitma:TM0399.
PATRICi23935681. VBITheMar51294_0404.

Phylogenomic databases

eggNOGiENOG4105CK6. Bacteria.
COG0745. LUCA.
InParanoidiQ9WYN0.
OMAiDNHTTPV.

Miscellaneous databases

EvolutionaryTraceiQ9WYN0.

Family and domain databases

CDDicd00383. trans_reg_C. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR001867. OmpR/PhoB-type_DNA-bd.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS51755. OMPR_PHOB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9WYN0_THEMA
AccessioniPrimary (citable) accession number: Q9WYN0
Secondary accession number(s): G4FHV8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: May 10, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.