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Q9WYN0

- Q9WYN0_THEMA

UniProt

Q9WYN0 - Q9WYN0_THEMA

Protein
Submitted name:

Response regulator

Gene

TM_0399

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 Nov 1999)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi10 – 101MagnesiumImported
    Metal bindingi53 – 531MagnesiumImported
    Metal bindingi55 – 551MagnesiumImported

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. metal ion binding Source: UniProtKB-KW
    3. phosphorelay response regulator activity Source: InterPro

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: InterPro

    Keywords - Biological processi

    Transcription, Transcription regulationSAAS annotation, Two-component regulatory systemSAAS annotation

    Keywords - Ligandi

    MagnesiumImported, Metal-bindingImported

    Enzyme and pathway databases

    BioCyciTMAR243274:GC6P-414-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Response regulatorImported
    Gene namesi
    Ordered Locus Names:TM_0399Imported
    OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
    Taxonomic identifieri243274 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
    ProteomesiUP000008183: Chromosome

    PTM / Processingi

    Keywords - PTMi

    PhosphoproteinSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi243274.TM0399.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1KGSX-ray1.50A1-225[»]
    3NNNX-ray2.20A/B1-122[»]
    ProteinModelPortaliQ9WYN0.
    SMRiQ9WYN0. Positions 2-225.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ9WYN0.

    Family & Domainsi

    Sequence similaritiesi

    Contains response regulatory domain.SAAS annotation

    Phylogenomic databases

    KOiK02483.
    OMAiKKLPERT.
    OrthoDBiEOG6G4VQG.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR011006. CheY-like_superfamily.
    IPR001867. Sig_transdc_resp-reg_C.
    IPR001789. Sig_transdc_resp-reg_receiver.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00072. Response_reg. 1 hit.
    PF00486. Trans_reg_C. 1 hit.
    [Graphical view]
    SMARTiSM00448. REC. 1 hit.
    SM00862. Trans_reg_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52172. SSF52172. 1 hit.
    PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9WYN0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNVRVLVVED ERDLADLITE ALKKEMFTVD VCYDGEEGMY MALNEPFDVV    50
    ILDIMLPVHD GWEILKSMRE SGVNTPVLML TALSDVEYRV KGLNMGADDY 100
    LPKPFDLREL IARVRALIRR KSESKSTKLV CGDLILDTAT KKAYRGSKEI 150
    DLTKKEYQIL EYLVMNKNRV VTKEELQEHL WSFDDEVFSD VLRSHIKNLR 200
    KKVDKGFKKK IIHTVRGIGY VARDE 225
    Length:225
    Mass (Da):26,015
    Last modified:November 1, 1999 - v1
    Checksum:i4CB1F2CC82A218F7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000512 Genomic DNA. Translation: AAD35484.1.
    PIRiH72382.
    RefSeqiNP_228209.1. NC_000853.1.

    Genome annotation databases

    EnsemblBacteriaiAAD35484; AAD35484; TM_0399.
    GeneIDi897392.
    KEGGitma:TM0399.
    PATRICi23935681. VBITheMar51294_0404.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000512 Genomic DNA. Translation: AAD35484.1 .
    PIRi H72382.
    RefSeqi NP_228209.1. NC_000853.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1KGS X-ray 1.50 A 1-225 [» ]
    3NNN X-ray 2.20 A/B 1-122 [» ]
    ProteinModelPortali Q9WYN0.
    SMRi Q9WYN0. Positions 2-225.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243274.TM0399.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD35484 ; AAD35484 ; TM_0399 .
    GeneIDi 897392.
    KEGGi tma:TM0399.
    PATRICi 23935681. VBITheMar51294_0404.

    Phylogenomic databases

    KOi K02483.
    OMAi KKLPERT.
    OrthoDBi EOG6G4VQG.

    Enzyme and pathway databases

    BioCyci TMAR243274:GC6P-414-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q9WYN0.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR011006. CheY-like_superfamily.
    IPR001867. Sig_transdc_resp-reg_C.
    IPR001789. Sig_transdc_resp-reg_receiver.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00072. Response_reg. 1 hit.
    PF00486. Trans_reg_C. 1 hit.
    [Graphical view ]
    SMARTi SM00448. REC. 1 hit.
    SM00862. Trans_reg_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52172. SSF52172. 1 hit.
    PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099Imported.
    2. "Evidence of intradomain and interdomain flexibility in an OmpR/PhoB homolog from Thermotoga maritima."
      Buckler D.R., Zhou Y., Stock A.M.
      Structure 10:153-164(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    3. "Regulation of response regulator autophosphorylation through interdomain contacts."
      Barbieri C.M., Mack T.R., Robinson V.L., Miller M.T., Stock A.M.
      J. Biol. Chem. 285:32325-32335(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 1-122 IN COMPLEX WITH MAGNESIUM.

    Entry informationi

    Entry nameiQ9WYN0_THEMA
    AccessioniPrimary (citable) accession number: Q9WYN0
    Secondary accession number(s): G4FHV8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1999
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3