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Q9WYN0

- Q9WYN0_THEMA

UniProt

Q9WYN0 - Q9WYN0_THEMA

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Protein
Submitted name:

Response regulator

Gene
TM_0399
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi10 – 101MagnesiumImported
Metal bindingi53 – 531MagnesiumImported
Metal bindingi55 – 551MagnesiumImported

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
  3. phosphorelay response regulator activity Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumImported, Metal-bindingImported

Enzyme and pathway databases

BioCyciTMAR243274:GC6P-414-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Response regulatorImported
Gene namesi
Ordered Locus Names:TM_0399Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
ProteomesiUP000008183: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0399.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1KGSX-ray1.50A1-225[»]
3NNNX-ray2.20A/B1-122[»]
ProteinModelPortaliQ9WYN0.
SMRiQ9WYN0. Positions 2-225.

Miscellaneous databases

EvolutionaryTraceiQ9WYN0.

Family & Domainsi

Phylogenomic databases

KOiK02483.
OMAiKKLPERT.
OrthoDBiEOG6G4VQG.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view]
SMARTiSM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9WYN0-1 [UniParc]FASTAAdd to Basket

« Hide

MNVRVLVVED ERDLADLITE ALKKEMFTVD VCYDGEEGMY MALNEPFDVV    50
ILDIMLPVHD GWEILKSMRE SGVNTPVLML TALSDVEYRV KGLNMGADDY 100
LPKPFDLREL IARVRALIRR KSESKSTKLV CGDLILDTAT KKAYRGSKEI 150
DLTKKEYQIL EYLVMNKNRV VTKEELQEHL WSFDDEVFSD VLRSHIKNLR 200
KKVDKGFKKK IIHTVRGIGY VARDE 225
Length:225
Mass (Da):26,015
Last modified:November 1, 1999 - v1
Checksum:i4CB1F2CC82A218F7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000512 Genomic DNA. Translation: AAD35484.1.
PIRiH72382.
RefSeqiNP_228209.1. NC_000853.1.

Genome annotation databases

EnsemblBacteriaiAAD35484; AAD35484; TM_0399.
GeneIDi897392.
KEGGitma:TM0399.
PATRICi23935681. VBITheMar51294_0404.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000512 Genomic DNA. Translation: AAD35484.1 .
PIRi H72382.
RefSeqi NP_228209.1. NC_000853.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1KGS X-ray 1.50 A 1-225 [» ]
3NNN X-ray 2.20 A/B 1-122 [» ]
ProteinModelPortali Q9WYN0.
SMRi Q9WYN0. Positions 2-225.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243274.TM0399.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD35484 ; AAD35484 ; TM_0399 .
GeneIDi 897392.
KEGGi tma:TM0399.
PATRICi 23935681. VBITheMar51294_0404.

Phylogenomic databases

KOi K02483.
OMAi KKLPERT.
OrthoDBi EOG6G4VQG.

Enzyme and pathway databases

BioCyci TMAR243274:GC6P-414-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q9WYN0.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view ]
SMARTi SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52172. SSF52172. 1 hit.
PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
  2. "Evidence of intradomain and interdomain flexibility in an OmpR/PhoB homolog from Thermotoga maritima."
    Buckler D.R., Zhou Y., Stock A.M.
    Structure 10:153-164(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
  3. "Regulation of response regulator autophosphorylation through interdomain contacts."
    Barbieri C.M., Mack T.R., Robinson V.L., Miller M.T., Stock A.M.
    J. Biol. Chem. 285:32325-32335(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 1-122 IN COMPLEX WITH MAGNESIUM.

Entry informationi

Entry nameiQ9WYN0_THEMA
AccessioniPrimary (citable) accession number: Q9WYN0
Secondary accession number(s): G4FHV8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: July 9, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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