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Protein
Submitted name:

Uncharacterized protein

Gene

TM_0312

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei78 – 781NADP; via carbonyl oxygenCombined sources
Binding sitei129 – 1291NADPCombined sources
Binding sitei279 – 2791NADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi14 – 174NADPCombined sources
Nucleotide bindingi40 – 456NADPCombined sources
Nucleotide bindingi100 – 1012NADPCombined sources
Nucleotide bindingi173 – 1742NADPCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Enzyme and pathway databases

BioCyciTMAR243274:GC6P-325-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:TM_0312Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0312.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZH8X-ray2.50A/B1-328[»]
ProteinModelPortaliQ9WYE8.
SMRiQ9WYE8. Positions 4-328.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9WYE8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 126120GFO_IDH_MocAInterPro annotationAdd
BLAST
Domaini140 – 20162GFO_IDH_MocA_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4107T86. Bacteria.
COG0673. LUCA.
InParanoidiQ9WYE8.
OMAiRMLVGCE.
OrthoDBiEOG69GZJ7.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9WYE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPLRKIRLG IVGCGIAARE LHLPALKNLS HLFEITAVTS RTRSHAEEFA
60 70 80 90 100
KMVGNPAVFD SYEELLESGL VDAVDLTLPV ELNLPFIEKA LRKGVHVICE
110 120 130 140 150
KPISTDVETG KKVVELSEKS EKTVYIAENF RHVPAFWKAK ELVESGAIGD
160 170 180 190 200
PVFMNWQIWV GMDENNKYVH TDWRKKPKHV GGFLSDGGVH HAAAMRLILG
210 220 230 240 250
EIEWISAVAK DLSPLLGGMD FLSSIFEFEN GTVGNYTISY SLKGNERFEI
260 270 280 290 300
TGTKGKISIS WDKIVLNEEE MKVPQENSYQ KEFEDFYQVV AEGKPNDLGS
310 320
PVQALKDLAF IEACVRSAGN KVFVSSLL
Length:328
Mass (Da):36,539
Last modified:November 1, 1999 - v1
Checksum:i93E2B37D4518544B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35400.1.
PIRiG72391.
RefSeqiNP_228124.1. NC_000853.1.
WP_010865093.1. NC_000853.1.

Genome annotation databases

EnsemblBacteriaiAAD35400; AAD35400; TM_0312.
GeneIDi897250.
KEGGitma:TM0312.
PATRICi23935503. VBITheMar51294_0317.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35400.1.
PIRiG72391.
RefSeqiNP_228124.1. NC_000853.1.
WP_010865093.1. NC_000853.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZH8X-ray2.50A/B1-328[»]
ProteinModelPortaliQ9WYE8.
SMRiQ9WYE8. Positions 4-328.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM0312.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD35400; AAD35400; TM_0312.
GeneIDi897250.
KEGGitma:TM0312.
PATRICi23935503. VBITheMar51294_0317.

Phylogenomic databases

eggNOGiENOG4107T86. Bacteria.
COG0673. LUCA.
InParanoidiQ9WYE8.
OMAiRMLVGCE.
OrthoDBiEOG69GZJ7.

Enzyme and pathway databases

BioCyciTMAR243274:GC6P-325-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ9WYE8.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099Imported.
  2. "Crystal structure of Oxidoreductase (TM0312) from Thermotoga maritima at 2.50 A resolution."
    Joint Center for Structural Genomics (JCSG)
    Submitted (APR-2005) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) IN COMPLEX WITH NADP.

Entry informationi

Entry nameiQ9WYE8_THEMA
AccessioniPrimary (citable) accession number: Q9WYE8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: March 16, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.