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Protein

Uncharacterized ABC transporter ATP-binding protein TM_0288

Gene

TM_0288

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi388 – 395ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi3.A.1.135.5 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized ABC transporter ATP-binding protein TM_0288
Gene namesi
Ordered Locus Names:TM_0288
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei80 – 100HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei150 – 170HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei177 – 197HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei273 – 293HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000932791 – 598Uncharacterized ABC transporter ATP-binding protein TM_0288Add BLAST598

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TM_0287Q9WYC34EBI-15975794,EBI-15975772

Protein-protein interaction databases

IntActiQ9WYC4, 1 interactor
STRINGi243274.TM0288

Structurei

Secondary structure

1598
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi21 – 28Combined sources8
Turni29 – 31Combined sources3
Helixi33 – 35Combined sources3
Helixi36 – 66Combined sources31
Turni67 – 71Combined sources5
Helixi73 – 75Combined sources3
Helixi76 – 122Combined sources47
Helixi125 – 130Combined sources6
Helixi133 – 152Combined sources20
Helixi154 – 175Combined sources22
Helixi177 – 183Combined sources7
Helixi186 – 224Combined sources39
Helixi226 – 231Combined sources6
Turni232 – 234Combined sources3
Helixi235 – 259Combined sources25
Turni260 – 262Combined sources3
Helixi263 – 287Combined sources25
Helixi293 – 301Combined sources9
Turni302 – 306Combined sources5
Helixi308 – 333Combined sources26
Beta strandi355 – 362Combined sources8
Beta strandi364 – 368Combined sources5
Beta strandi370 – 378Combined sources9
Beta strandi383 – 387Combined sources5
Helixi394 – 401Combined sources8
Beta strandi408 – 414Combined sources7
Helixi419 – 421Combined sources3
Helixi424 – 429Combined sources6
Beta strandi431 – 434Combined sources4
Beta strandi442 – 444Combined sources3
Helixi445 – 449Combined sources5
Turni450 – 452Combined sources3
Helixi458 – 467Combined sources10
Helixi471 – 475Combined sources5
Helixi480 – 482Combined sources3
Helixi486 – 489Combined sources4
Helixi494 – 507Combined sources14
Beta strandi511 – 516Combined sources6
Beta strandi520 – 522Combined sources3
Helixi524 – 538Combined sources15
Beta strandi541 – 546Combined sources6
Helixi552 – 555Combined sources4
Beta strandi557 – 563Combined sources7
Beta strandi566 – 571Combined sources6
Helixi573 – 579Combined sources7
Helixi582 – 591Combined sources10
Helixi592 – 596Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QF4X-ray2.90B1-598[»]
4Q4AX-ray2.60B1-598[»]
4Q4HX-ray2.53B1-598[»]
4Q4JX-ray3.20B1-598[»]
4Q7LX-ray2.35A/B/C353-598[»]
4Q7MX-ray2.30B353-598[»]
ProteinModelPortaliQ9WYC4
SMRiQ9WYC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 322ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST284
Domaini355 – 589ABC transporterPROSITE-ProRule annotationAdd BLAST235

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105BZ1 Bacteria
COG1132 LUCA
InParanoidiQ9WYC4
KOiK06147
OMAiFNQFFVG

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9WYC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEIRRRPHG PILEKPALKN PTATLRRLLG YLRPHTFTLI MVFVFVTVSS
60 70 80 90 100
ILGVLSPYLI GKTIDVVFVP RRFDLLPRYM LILGTIYALT SLLFWLQGKI
110 120 130 140 150
MLTLSQDVVF RLRKELFEKL QRVPVGFFDR TPHGDIISRV INDVDNINNV
160 170 180 190 200
LGNSIIQFFS GIVTLAGAVI MMFRVNVILS LVTLSIVPLT VLITQIVSSQ
210 220 230 240 250
TRKYFYENQR VLGQLNGIIE EDISGLTVIK LFTREEKEME KFDRVNESLR
260 270 280 290 300
KVGTKAQIFS GVLPPLMNMV NNLGFALISG FGGWLALKDI ITVGTIATFI
310 320 330 340 350
GYSRQFTRPL NELSNQFNMI QMALASAERI FEILDLEEEK DDPDAVELRE
360 370 380 390 400
VRGEIEFKNV WFSYDKKKPV LKDITFHIKP GQKVALVGPT GSGKTTIVNL
410 420 430 440 450
LMRFYDVDRG QILVDGIDIR KIKRSSLRSS IGIVLQDTIL FSTTVKENLK
460 470 480 490 500
YGNPGATDEE IKEAAKLTHS DHFIKHLPEG YETVLTDNGE DLSQGQRQLL
510 520 530 540 550
AITRAFLANP KILILDEATS NVDTKTEKSI QAAMWKLMEG KTSIIIAHRL
560 570 580 590
NTIKNADLII VLRDGEIVEM GKHDELIQKR GFYYELFTSQ YGLVVEKE
Length:598
Mass (Da):67,708
Last modified:November 1, 1999 - v1
Checksum:iBDFA5A242F18393E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA Translation: AAD35376.1
PIRiF72396
RefSeqiNP_228100.1, NC_000853.1
WP_004083002.1, NZ_CP011107.1

Genome annotation databases

EnsemblBacteriaiAAD35376; AAD35376; TM_0288
GeneIDi897208
KEGGitma:TM0288

Similar proteinsi

Entry informationi

Entry nameiY288_THEMA
AccessioniPrimary (citable) accession number: Q9WYC4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health