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Protein
Submitted name:

ABC transporter, ATP-binding protein

Gene

TM_0287

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei105ATP analogCombined sources1
Binding sitei341ATP analogCombined sources1
Metal bindingi373MagnesiumCombined sources1
Metal bindingi414MagnesiumCombined sources1
Binding sitei414ATP analogCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi368 – 374ATP analogCombined sources7

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotationImported, MagnesiumCombined sources, Metal-bindingCombined sources, Nucleotide-binding

Protein family/group databases

TCDBi3.A.1.135.5. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Submitted name:
ABC transporter, ATP-binding proteinImported
Submitted name:
Lipid A export ATP-binding/permease protein MsbAImported
Gene namesi
Ordered Locus Names:TM_0287Imported
ORF Names:Tmari_0285Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000013901 Componenti: Chromosome
  • UP000008183 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 36HelicalSequence analysisAdd BLAST25
Transmembranei56 – 80HelicalSequence analysisAdd BLAST25
Transmembranei133 – 151HelicalSequence analysisAdd BLAST19
Transmembranei157 – 174HelicalSequence analysisAdd BLAST18
Transmembranei229 – 258HelicalSequence analysisAdd BLAST30
Transmembranei278 – 297HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0287.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QF4X-ray2.90A2-577[»]
4Q4AX-ray2.60A2-577[»]
4Q4HX-ray2.53A2-577[»]
4Q4JX-ray3.20A2-577[»]
4Q7KX-ray1.80A330-577[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 298ABC transmembrane type-1InterPro annotationAdd BLAST283
Domaini332 – 567ABC transporterInterPro annotationAdd BLAST236

Sequence similaritiesi

Contains 1 ABC transporter domain.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZ1. Bacteria.
COG1132. LUCA.
KOiK06147.
OMAiFRYFENT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9WYC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLARYLKP YWIFAVLAPL FMVVEVICDL SQPTLLARIV DEGIARGDFS
60 70 80 90 100
LVLKTGILML IVALIGAVGG IGCTVFASYA SQNFGADLRR DLFRKVLSFS
110 120 130 140 150
ISNVNRFHTS SLITRLTNDV TQLQNLVMML LRIVVRAPLL FVGGIVMAVS
160 170 180 190 200
INVKLSSVLI FLIPPIVLLF VWLTKKGNPL FRKIQESTDE VNRVVRENLL
210 220 230 240 250
GVRVVRAFRR EEYENENFRK ANESLRRSII SAFSLIVFAL PLFIFIVNMG
260 270 280 290 300
MIAVLWFGGV LVRNNQMEIG SIMAYTNYLM QIMFSLMMIG NILNFIVRAS
310 320 330 340 350
ASAKRVLEVL NEKPAIEEAD NALALPNVEG SVSFENVEFR YFENTDPVLS
360 370 380 390 400
GVNFSVKPGS LVAVLGETGS GKSTLMNLIP RLIDPERGRV EVDELDVRTV
410 420 430 440 450
KLKDLRGHIS AVPQETVLFS GTIKENLKWG REDATDDEIV EAAKIAQIHD
460 470 480 490 500
FIISLPEGYD SRVERGGRNF SGGQKQRLSI ARALVKKPKV LILDDCTSSV
510 520 530 540 550
DPITEKRILD GLKRYTKGCT TFIITQKIPT ALLADKILVL HEGKVAGFGT
560 570
HKELLEHCKP YREIYESQFG NGVMNDA
Length:577
Mass (Da):64,360
Last modified:November 1, 1999 - v1
Checksum:iA53DFED7694B8F44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35375.1.
CP004077 Genomic DNA. Translation: AGL49211.1.
PIRiE72396.
RefSeqiNP_228099.1. NC_000853.1.
WP_004083000.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD35375; AAD35375; TM_0287.
AGL49211; AGL49211; Tmari_0285.
GeneIDi897207.
KEGGitma:TM0287.
tmi:THEMA_03290.
tmm:Tmari_0285.
tmw:THMA_0294.
PATRICi23935453. VBITheMar51294_0292.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35375.1.
CP004077 Genomic DNA. Translation: AGL49211.1.
PIRiE72396.
RefSeqiNP_228099.1. NC_000853.1.
WP_004083000.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QF4X-ray2.90A2-577[»]
4Q4AX-ray2.60A2-577[»]
4Q4HX-ray2.53A2-577[»]
4Q4JX-ray3.20A2-577[»]
4Q7KX-ray1.80A330-577[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM0287.

Protein family/group databases

TCDBi3.A.1.135.5. the atp-binding cassette (abc) superfamily.

Protocols and materials databases

DNASUi897207.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD35375; AAD35375; TM_0287.
AGL49211; AGL49211; Tmari_0285.
GeneIDi897207.
KEGGitma:TM0287.
tmi:THEMA_03290.
tmm:Tmari_0285.
tmw:THMA_0294.
PATRICi23935453. VBITheMar51294_0292.

Phylogenomic databases

eggNOGiENOG4105BZ1. Bacteria.
COG1132. LUCA.
KOiK06147.
OMAiFRYFENT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9WYC3_THEMA
AccessioniPrimary (citable) accession number: Q9WYC3
Secondary accession number(s): G4FHK1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: November 2, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.