Q9WY82 (GLGC_THEMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-1-phosphate adenylyltransferase
EC=2.7.7.27

Alternative name(s):
ADP-glucose pyrophosphorylase
Short name=ADPGlc PPase
ADP-glucose synthase

Gene names

Name:	glgC
Ordered Locus Names:	TM_0240

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	423 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans By similarity. HAMAP MF_00624
Catalytic activity	ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose. HAMAP MF_00624
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00624
Sequence similarities	Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen biosynthesis Glycogen metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glucose-1-phosphate adenylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 423	423	Glucose-1-phosphate adenylyltransferase HAMAP MF_00624		PRO_0000195340

Sequences

	Sequence		Length	Mass (Da)
	Q9WY82 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 013DE78538FCC62E	FASTA	423	47,139
	10 20 30 40 50 60 MGNTVAMILA GGQGTRLGVL TERIAKPAVP FGGKYRLIDF TLSNCVNSGI YRVGVLTQYR 70 80 90 100 110 120 PHVLSKHIGI GRPWDLDRKD GGVEILPPYV GRHESDWYKG TANAVYQNLE FLEENDAELV 130 140 150 160 170 180 LILSGDHVYA MNYNDLIDYH LLKEADGTIA CMEVPIEEAS RFGIMITDVD GRIVDFEEKP 190 200 210 220 230 240 AKPRSNLASL GIYVFNYEFL KKVLIEDEND PNSSHDFGKD VIPRILRENL GSLYAFRFDG 250 260 270 280 290 300 YWRDVGTLRS YWEANLELVL PVPPFNLYDP NWRFFTHTEE MPPAYVAPGS KVSTSLVSEG 310 320 330 340 350 360 AEVYGNVFNS VIFQGVKIGR GTVVKNSVIM TRTEIGENCY LENVIIAENV KIGSNVRMGV 370 380 390 400 410 420 GEDAESKLDP KVYSGLLTVV GMNSVIPDDM VIGKNCVIGI GVRPEDFKSK TLESGDYVIV REE

References

[1]

"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000512 Genomic DNA. Translation: AAD35331.1.
PIR	B72403.
RefSeq	NP_228054.1. NC_000853.1.
3D structure databases
ProteinModelPortal	Q9WY82.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	897141.
GenomeReviews	Gene locus TM_0240 in contig AE000512_GR.
KEGG	tma:TM0240.
NMPDR	fig|243274.1.peg.238.
PATRIC	23935355. VBITheMar51294_0243.
TIGR	TM_0240.
Phylogenomic databases
HOGENOM	HBG703946.
OMA	DPLMLAR.
PhylomeDB	Q9WY82.
ProtClustDB	PRK05293.
Enzyme and pathway databases
BioCyc	TMAR243274:TM_0240-MONOMER.
Family and domain databases
HAMAP	MF_00624. GlgC. [Tree]
InterPro	IPR005836. ADP_Glu_pyroP_CS. IPR011831. GlgC. IPR023049. GlgC_bac. IPR001451. Hexapep_transf. IPR005835. NTP_transferase. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00975.
Pfam	PF00132. Hexapep. 1 hit. PF00483. NTP_transferase. 1 hit. [Graphical view]
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR02091. GlgC. 1 hit.
PROSITE	PS00808. ADP_GLC_PYROPHOSPH_1. 1 hit. PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit. PS00810. ADP_GLC_PYROPHOSPH_3. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLGC_THEMA

Accession

Primary (citable) accession number: Q9WY82

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	November 1, 1999
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program