Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9WY59 (SYGA_THEMA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:TM_0216
OrganismThermotoga maritima
Taxonomic identifier2336 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm HAMAP MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 286286Glycine--tRNA ligase alpha subunit HAMAP MF_00254
PRO_0000072877

Secondary structure

1 ........................................ 286
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9WY59 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 9B8061D54B1160F2

FASTA28633,540
        10         20         30         40         50         60 
MYLQDVIMKL NDFWASKGCL LEQPYDMEVG AGTFHPATFF GSLRKGPWKV AYVQPSRRPT 

        70         80         90        100        110        120 
DGRYGENPNR LQRYFQYQVI IKPSPENSQE LYLESLEYLG INLKEHDIRF VEDNWESPTL 

       130        140        150        160        170        180 
GAWGVGWEVW LDGMEITQFT YFQQIGGISL KDIPLEITYG LERIAMYLQG VDNVYEVQWN 

       190        200        210        220        230        240 
ENVKYGDVFL ENEREFSVFN FEEANVGLLF RHFDEYEKEF YRLVEKNLYL PAYDYILKCS 

       250        260        270        280 
HTFNLLDARG AISVSQRQTY VKRIQAMARK AARVFLEVQA NENSPA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000512 Genomic DNA. Translation: AAD35308.1.
PIRB72404.
RefSeqNP_228031.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1J5WX-ray1.95A/B1-286[»]
ProteinModelPortalQ9WY59.
SMRQ9WY59. Positions 1-280.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID897101.
GenomeReviewsGene locus TM_0216 in contig AE000512_GR.
KEGGtma:TM0216.
NMPDRfig|243274.1.peg.215.
PATRIC23935304. VBITheMar51294_0218.
TIGRTM_0216.

Phylogenomic databases

HOGENOMHBG285316.
OMACRRPTDG.
PhylomeDBQ9WY59.
ProtClustDBPRK09348.

Enzyme and pathway databases

BioCycTMAR243274:TM_0216-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
[Tree]
InterProIPR006194. Gly-tRNA-synth_II_heterodimer.
IPR002310. Gly-tRNA_synth_IIc_asu.
[Graphical view]
KOK01878.
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. GlyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_THEMA
AccessionPrimary (citable) accession number: Q9WY59
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: January 25, 2012
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents