acpP

Functionⁱ

Carrier of the growing fatty acid chain in fatty acid biosynthesis.UniRule annotationSAAS annotation

Pathwayⁱ: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

GO - Molecular functionⁱ

ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Source: UniProtKB-HAMAP

Complete GO annotation...

Keywordsⁱ

Biological process	Fatty acid biosynthesisUniRule annotationSAAS annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Biological process

Fatty acid biosynthesisUniRule annotationSAAS annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

UniPathwayⁱ	UPA00094.

UniPathwayⁱ

UPA00094.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Acyl carrier proteinUniRule annotation Short name: ACPUniRule annotation
Gene namesⁱ	Name:acpPUniRule annotation Ordered Locus Names:TM_0175Imported
Organismⁱ	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifierⁱ	243274 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Thermotogae › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga › Thermotoga maritima
Proteomesⁱ	UP000008183 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Automatic assertion according to rulesⁱ
- HAMAP-Rule:MF_01217

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

CytoplasmUniRule annotation

PTM / Processingⁱ

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	38	O-(pantetheine 4'-phosphoryl)serineUniRule annotation		1

Post-translational modificationⁱ

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.UniRule annotation

Keywords - PTMⁱ

PhosphopantetheineUniRule annotation, PhosphoproteinUniRule annotation

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	243274.TM0175.

STRINGⁱ

243274.TM0175.

Structureⁱ

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1VKU	X-ray	2.00	A	1-88	[»]
SMRⁱ	Q9WY19.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the acyl carrier protein (ACP) family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	COG0236. LUCA.
KEGG Orthology (KO) More...KOⁱ	K02078.
OMAⁱ	MFFEDEF.

Family and domain databases

HAMAPⁱ	MF_01217. Acyl_carrier. 1 hit.
InterProⁱ	View protein in InterPro IPR003231. Acyl_carrier. IPR009081. PP-bd_ACP. IPR006162. Ppantetheine_attach_site.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00550. PP-binding. 1 hit.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD000887. PD000887. 1 hit.
SUPFAMⁱ	SSF47336. SSF47336. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9WY19-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MERKKLIAKF VEIASEKMGK DLETVDEENT FKELGFDSID VIDLVMFFED 
        60         70         80 
EFALRIEDEE ISKIRKVKDL IDIVIKKLEE IDDEVSEG

Length:88

Mass (Da):10,285

Last modified:November 1, 1999 - v1

Checksum:ⁱDF44279D407CA06B

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE000512 Genomic DNA. Translation: AAD35268.1.
PIRⁱ	E72409.
NCBI Reference Sequences More...RefSeqⁱ	NP_227990.1. NC_000853.1. WP_004082810.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAD35268; AAD35268; TM_0175. AGL49099; AGL49099; Tmari_0173.
GeneIDⁱ	897015.
KEGGⁱ	tma:TM0175. tmi:THEMA_03925. tmm:Tmari_0173. tmw:THMA_0171.
PATRICⁱ	fig\|243274.17.peg.173.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q9WY19	R4NXG3 UPI0000683505	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	88	UniRef100_R4NXG3	Cluster: Acyl carrier protein	3

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q9WY19	Q5CB66 A0A0A7RQ99 A0A0B5GUJ5 Q5CBL2 Q5CBJ4 A5IKP6 R4NXG3 UPI0000683505 UPI000319D0B7 UPI000280EA1F +2	Thermotoga sp. (strain RQ2) Thermotoga sp. TBYP3.1.4.1 Thermotoga sp. TBXY761 Thermotoga naphthophila Thermotoga petrophila Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995) Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) Thermotoga Thermotoga naphthophila (strain ATCC BAA-489 / DSM 13996 / JCM 10882 / RKU-10) Thermotoga sp. Mc24	93	UniRef90_Q5CB66	Cluster: Acyl carrier protein	13

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q9WY19	Q5CB66 A0A0A7RQ99 A0A0B5GUJ5 Q5CBL2 Q5CBJ4 A5IKP6 D2C7G3 UPI000280EA1F R4NXG3 UPI0000683505 +2	Thermotoga sp. (strain RQ2) Thermotoga sp. TBYP3.1.4.1 Thermotoga sp. TBXY761 Thermotoga naphthophila Thermotoga petrophila Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995) Thermotoga naphthophila (strain ATCC BAA-489 / DSM 13996 / JCM 10882 / RKU-10) Thermotoga Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) Thermotoga sp. Mc24	93	UniRef50_Q5CB66	Cluster: Acyl carrier protein	13

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE000512 Genomic DNA. Translation: AAD35268.1.
PIRⁱ	E72409.
NCBI Reference Sequences More...RefSeqⁱ	NP_227990.1. NC_000853.1. WP_004082810.1. NZ_CP011107.1.

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1VKU	X-ray	2.00	A	1-88	[»]
SMRⁱ	Q9WY19.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	243274.TM0175.

STRINGⁱ

243274.TM0175.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAD35268; AAD35268; TM_0175. AGL49099; AGL49099; Tmari_0173.
GeneIDⁱ	897015.
KEGGⁱ	tma:TM0175. tmi:THEMA_03925. tmm:Tmari_0173. tmw:THMA_0171.
PATRICⁱ	fig\|243274.17.peg.173.

Phylogenomic databases

eggNOGⁱ	COG0236. LUCA.
KEGG Orthology (KO) More...KOⁱ	K02078.
OMAⁱ	MFFEDEF.

Enzyme and pathway databases

UniPathwayⁱ	UPA00094.

UniPathwayⁱ

UPA00094.

Family and domain databases

HAMAPⁱ	MF_01217. Acyl_carrier. 1 hit.
InterProⁱ	View protein in InterPro IPR003231. Acyl_carrier. IPR009081. PP-bd_ACP. IPR006162. Ppantetheine_attach_site.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00550. PP-binding. 1 hit.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD000887. PD000887. 1 hit.
SUPFAMⁱ	SSF47336. SSF47336. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q9WY19_THEMA
Accessionⁱ	Q9WY19Primary (citable) accession number: Q9WY19 Secondary accession number(s): G4FH89
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 1, 1999
	Last sequence update:	November 1, 1999
	Last modified:	August 30, 2017
	This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termⁱ

3D-structureCombined sources, Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9WY19 (Q9WY19_THEMA)

Your basket is currently empty.

Acyl carrier protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: fatty acid biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

Pathwayⁱ: fatty acid biosynthesis

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ