Q9WXT2 (Q9WXT2_THEMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Acetyl xylan esterase EMBL AAD35171.1

Gene names

Ordered Locus Names:

TM_0077

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	325 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Calcium PDB 3M81 PDB 3M82 PDB 3M83 Metal-binding PDB 3M81 PDB 3M82 PDB 3M83
Technical term	3D-structure PDB 3M81 PDB 3M82 PDB 3M83 PDB 1VLQ Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	22	1	Calcium; via carbonyl oxygen PDB 3M81 PDB 3M82 PDB 3M83
	Metal binding	26	1	Calcium PDB 3M81 PDB 3M82 PDB 3M83

Sequences

	Sequence		Length	Mass (Da)
	Q9WXT2 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: AF2879D86680A3C4	FASTA	325	37,156
	10 20 30 40 50 60 MAFFDLPLEE LKKYRPERYE EKDFDEFWEE TLAESEKFPL DPVFERMESH LKTVEAYDVT 70 80 90 100 110 120 FSGYRGQRIK GWLLVPKLEE EKLPCVVQYI GYNGGRGFPH DWLFWPSMGY ICFVMDTRGQ 130 140 150 160 170 180 GSGWLKGDTP DYPEGPVDPQ YPGFMTRGIL DPRTYYYRRV FTDAVRAVEA AASFPQVDQE 190 200 210 220 230 240 RIVIAGGSQG GGIALAVSAL SKKAKALLCD VPFLCHFRRA VQLVDTHPYA EITNFLKTHR 250 260 270 280 290 300 DKEEIVFRTL SYFDGVNFAA RAKIPALFSV GLMDNICPPS TVFAAYNYYA GPKEIRIYPY 310 320 NNHEGGGSFQ AVEQVKFLKK LFEKG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Crystal structure of Acetyl xylan esterase (TM0077) from Thermotoga maritima at 2.10 A resolution." Joint Center for Structural Genomics (JCSG) Submitted (AUG-2004) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
[3]	"Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.12 A resolution (paraoxon inhibitor complex structure)." Joint Center for Structural Genomics (JCSG) Submitted (MAR-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.12 ANGSTROMS) IN COMPLEX WITH CALCIUM.
[4]	"Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.50 A resolution (native apo structure)." Joint Center for Structural Genomics (JCSG) Submitted (MAR-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) IN COMPLEX WITH CALCIUM.
[5]	"Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.40 A resolution (PMSF inhibitor complex structure)." Joint Center for Structural Genomics (JCSG) Submitted (MAR-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) IN COMPLEX WITH CALCIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD35171.1.

PIR

E72421.

RefSeq

NP_227893.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VLQ	X-ray	2.10	A/B/C/D/E/F/G/H/I/J/K/L	1-325	[»]
3M81	X-ray	2.50	A/B/C/D/E/F	1-325	[»]
3M82	X-ray	2.40	A/B/C/D/E/F	1-325	[»]
3M83	X-ray	2.12	A/B/C/D/E/F	1-325	[»]

ProteinModelPortal

Q9WXT2.

SMR

Q9WXT2. Positions 2-323.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

896903.

GenomeReviews

Gene locus TM_0077 in contig AE000512_GR.

KEGG

tma:TM0077.

NMPDR

fig|243274.1.peg.77.

PATRIC

23934994. VBITheMar51294_0075.

TIGR

TM_0077.

Phylogenomic databases

HOGENOM

HBG312403.

OMA

DNICPPS.

PhylomeDB

Q9WXT2.

ProtClustDB

CLSK864597.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_0077-MONOMER.

Family and domain databases

InterPro

IPR008391. AXE1.
[Graphical view]

KO

K01060.

Pfam

PF05448. AXE1. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q9WXT2_THEMA

Accession

Primary (citable) accession number: Q9WXT2

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)