2-keto-3-deoxygluconate kinase - Thermotoga maritima

Preferred order of sections

Names and origin

Protein names

Submitted name:
2-keto-3-deoxygluconate kinase EMBL AAD35161.1

Gene names

Ordered Locus Names:

TM_0067

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	339 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Calcium PDB 2AFB Metal-binding PDB 2AFB
Molecular function	Kinase EMBL AAD35161.1 Transferase
Technical term	3D-structure PDB 2AFB Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	kinase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

17

1

Calcium 1 PDB 2AFB

Metal binding

25

1

Calcium 2 PDB 2AFB

Metal binding

326

1

Calcium 2 PDB 2AFB

Sequences

Sequence

Length

Mass (Da)

Tools

Q9WXS2 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: DEE01C83C7E44D4C
Show »

FASTA

339

37,601

        10         20         30         40         50         60 
MKVVTFGEIM LRLSPPDHKR IFQTDSFDVT YGGAEANVAA FLAQMGLDAY FVTKLPNNPL 

        70         80         90        100        110        120 
GDAAAGHLRK FGVKTDYIAR GGNRIGIYFL EIGASQRPSK VVYDRAHSAI SEAKREDFDW 

       130        140        150        160        170        180 
EKILDGARWF HFSGITPPLG KELPLILEDA LKVANEKGVT VSCDLNYRAR LWTKEEAQKV 

       190        200        210        220        230        240 
MIPFMEYVDV LIANEEDIEK VLGISVEGLD LKTGKLNREA YAKIAEEVTR KYNFKTVGIT 

       250        260        270        280        290        300 
LRESISATVN YWSVMVFENG QPHFSNRYEI HIVDRVGAGD SFAGALIYGS LMGFDSQKKA 

       310        320        330 
EFAAAASCLK HTIPGDFVVL SIEEIEKLAS GATSGRVER

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution." Mathews I.I., McMullan D., Miller M.D., Canaves J.M., Elsliger M.A., Floyd R., Grzechnik S.K., Jaroszewski L., Klock H.E., Koesema E., Kovarik J.S., Kreusch A., Kuhn P., McPhillips T.M., Morse A.T., Quijano K., Rife C.L., Schwarzenbacher R. Wilson I.A. Proteins 70:603-608(2008) [PubMed: 18004772] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) IN COMPLEX WITH CALCIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD35161.1.

PIR

G72422.

RefSeq

NP_227883.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2AFB	X-ray	2.05	A/B	1-339	[»]

ProteinModelPortal

Q9WXS2.

SMR

Q9WXS2. Positions 1-331.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

896891.

GenomeReviews

Gene locus TM_0067 in contig AE000512_GR.

KEGG

tma:TM0067.

NMPDR

fig|243274.1.peg.67.

PATRIC

23934974. VBITheMar51294_0065.

TIGR

TM_0067.

Phylogenomic databases

HOGENOM

HBG697973.

OMA

HFSGITP.

PhylomeDB

Q9WXS2.

ProtClustDB

CLSK794883.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_0067-MONOMER.

Family and domain databases

InterPro

IPR011611. Carb/pur_kinase.
[Graphical view]

KO

K00874.

Pfam

PF00294. PfkB. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q9WXS2_THEMA

Accession

Primary (citable) accession number: Q9WXS2

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)