Q9WXS1 (Q9WXS1_THEMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase EMBL AAD35160.1

Gene names

Ordered Locus Names:

TM_0066

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1VLW PDB 1WA3 Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9WXS1 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 1ACBCF04B6B3EFA0	FASTA	205	22,236
	10 20 30 40 50 60 MKMEELFKKH KIVAVLRANS VEEAKEKALA VFEGGVHLIE ITFTVPDADT VIKELSFLKE 70 80 90 100 110 120 KGAIIGAGTV TSVEQCRKAV ESGAEFIVSP HLDEEISQFC KEKGVFYMPG VMTPTELVKA 130 140 150 160 170 180 MKLGHTILKL FPGEVVGPQF VKAMKGPFPN VKFVPTGGVN LDNVCEWFKA GVLAVGVGSA 190 200 LVKGTPDEVR EKAKAFVEKI RGCTE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Crystal structure of 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (TM0066) from Thermotoga maritima at 2.30 A resolution." Joint Center for Structural Genomics (JCSG) Submitted (AUG-2004) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).
[3]	"Mechanism of the Class I KDPG aldolase." Fullerton S.W., Griffiths J.S., Merkel A.B., Cheriyan M., Wymer N.J., Hutchins M.J., Fierke C.A., Toone E.J., Naismith J.H. Bioorg. Med. Chem. 14:3002-3010(2006) [PubMed: 16403639] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD35160.1.

PIR

F72422.

RefSeq

NP_227882.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VLW	X-ray	2.30	A/B/C	1-205	[»]
1WA3	X-ray	1.90	A/B/C/D/E/F	1-205	[»]

ProteinModelPortal

Q9WXS1.

SMR

Q9WXS1. Positions 1-204.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

896890.

GenomeReviews

Gene locus TM_0066 in contig AE000512_GR.

KEGG

tma:TM0066.

NMPDR

fig|243274.1.peg.66.

PATRIC

23934972. VBITheMar51294_0064.

TIGR

TM_0066.

Phylogenomic databases

HOGENOM

HBG670118.

OMA

HLDEEIS.

PhylomeDB

Q9WXS1.

ProtClustDB

CLSK794882.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_0066-MONOMER.

Family and domain databases

InterPro

IPR000887. Aldlse_KDPG_KHG.
IPR013785. Aldolase_TIM.
[Graphical view]

Gene3D

G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.

KO

K01625.

Pfam

PF01081. Aldolase. 1 hit.
[Graphical view]

TIGRFAMs

TIGR01182. Eda. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q9WXS1_THEMA

Accession

Primary (citable) accession number: Q9WXS1

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)