Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9WXR9 (UXAC_THEMA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uronate isomerase
EC=5.3.1.12
Alternative name(s):
Glucuronate isomerase
Uronic isomerase
Gene names
Name:uxaC
Ordered Locus Names:TM_0064
OrganismThermotoga maritima
Taxonomic identifier2336 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length451 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

D-glucuronate = D-fructuronate. HAMAP MF_00675

D-galacturonate = D-tagaturonate. HAMAP MF_00675

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00675

Subunit structure

Homotrimer.

Sequence similarities

Belongs to the uronate isomerase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionglucuronate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 451451Uronate isomerase HAMAP MF_00675
PRO_0000172789

Secondary structure

1 ......................................................................... 451
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9WXR9 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: FC0B3221F740B927

FASTA45152,306
        10         20         30         40         50         60 
MFLGEDYLLT NRAAVRLFNE VKDLPIVDPH NHLDAKDIVE NKPWNDIWEV EGATDHYVWE 

        70         80         90        100        110        120 
LMRRCGVSEE YITGSRSNKE KWLALAKVFP RFVGNPTYEW IHLDLWRRFN IKKVISEETA 

       130        140        150        160        170        180 
EEIWEETKKK LPEMTPQKLL RDMKVEILCT TDDPVSTLEH HRKAKEAVEG VTILPTWRPD 

       190        200        210        220        230        240 
RAMNVDKEGW REYVEKMGER YGEDTSTLDG FLNALWKSHE HFKEHGCVAS DHALLEPSVY 

       250        260        270        280        290        300 
YVDENRARAV HEKAFSGEKL TQDEINDYKA FMMVQFGKMN QETNWVTQLH IGALRDYRDS 

       310        320        330        340        350        360 
LFKTLGPDSG GDISTNFLRI AEGLRYFLNE FDGKLKIVLY VLDPTHLPTI STIARAFPNV 

       370        380        390        400        410        420 
YVGAPWWFND SPFGMEMHLK YLASVDLLYN LAGMVTDSRK LLSFGSRTEM FRRVLSNVVG 

       430        440        450 
EMVEKGQIPI KEARELVKHV SYDGPKALFF G

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000512 Genomic DNA. Translation: AAD35158.1.
PIRD72422.
RefSeqNP_227880.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1J5SX-ray2.85A/B/C1-451[»]
ProteinModelPortalQ9WXR9.
SMRQ9WXR9. Positions 1-450.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID896888.
GenomeReviewsGene locus TM_0064 in contig AE000512_GR.
KEGGtma:TM0064.
NMPDRfig|243274.1.peg.64.
PATRIC23934968. VBITheMar51294_0062.
TIGRTM_0064.

Phylogenomic databases

HOGENOMHBG297087.
OMAAWAKTVP.
PhylomeDBQ9WXR9.
ProtClustDBPRK02925.

Enzyme and pathway databases

BioCycTMAR243274:TM_0064-MONOMER.

Family and domain databases

HAMAPMF_00675. UxaC.
[Tree]
InterProIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
Gene3DG3DSA:1.10.2020.10. Uronate_isomerase_dom2. 1 hit.
KOK01812.
PfamPF02614. UxaC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUXAC_THEMA
AccessionPrimary (citable) accession number: Q9WXR9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents