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Protein

Ferrous iron transport protein B

Gene

TM_0051

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Fe2+ uptake system, probably driven by GTP.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Iron transportUniRule annotation, Transport

Keywords - Ligandi

GTP-bindingUniRule annotation, Iron, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ferrous iron transport protein BUniRule annotation
Gene namesi
Ordered Locus Names:TM_0051Imported
ORF Names:Tmari_0048Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000013901 Componenti: Chromosome
  • UP000008183 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei289 – 307HelicalUniRule annotationAdd BLAST19
Transmembranei345 – 369HelicalUniRule annotationAdd BLAST25
Transmembranei389 – 411HelicalUniRule annotationAdd BLAST23
Transmembranei423 – 449HelicalUniRule annotationAdd BLAST27
Transmembranei455 – 479HelicalUniRule annotationAdd BLAST25
Transmembranei517 – 536HelicalUniRule annotationAdd BLAST20
Transmembranei610 – 632HelicalUniRule annotationAdd BLAST23
Transmembranei644 – 666HelicalUniRule annotationAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0051.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3A1SX-ray1.50A/B17-269[»]
3A1TX-ray1.80A17-269[»]
3A1UX-ray1.80A/B17-269[»]
3A1VX-ray2.40A/B17-269[»]
3A1WX-ray1.90A17-179[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 178FeoB-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST163

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. [View classification]UniRule annotation
Contains 1 FeoB-type G (guanine nucleotide-binding) domain.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105CE1. Bacteria.
COG0370. LUCA.
KOiK04759.
OMAiIWYLSSY.

Family and domain databases

CDDicd01879. FeoB. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR003373. Fe2_transport_prot-B.
IPR011640. Fe2_transport_prot_B_C.
IPR030389. G_FEOB_dom.
IPR011642. Gate_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PANTHERiPTHR11649:SF37. PTHR11649:SF37. 2 hits.
PfamiPF07664. FeoB_C. 1 hit.
PF02421. FeoB_N. 1 hit.
PF07670. Gate. 2 hits.
[Graphical view]
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00437. feoB. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51711. G_FEOB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9WXQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVKSLTRRS EISQKIVKVA LAGCPNVGKT SLFNALTGTK QYVANWPGVT
60 70 80 90 100
VEKKEGVFTY KGYTINLIDL PGTYSLGYSS IDEKIARDYL LKGDADLVIL
110 120 130 140 150
VADSVNPEQS LYLLLEILEM EKKVILAMTA IDEAKKTGMK IDRYELQKHL
160 170 180 190 200
GIPVVFTSSV TGEGLEELKE KIVEYAQKNT ILHRMILDYG EKVESEIKKV
210 220 230 240 250
ENFLRDKKLR INPRYFALKY LSGDPEFYSE GVKLGLPELS EEERIGYRLL
260 270 280 290 300
IAKRKREYVE NVVKEAFADA GSKSLSLSEA IDHVLTHKFL SFPLFFALMY
310 320 330 340 350
LVFKFTFDIA QVFSDLLDLL FSQLGSAVVN TFGENAFTSL ISDGIIGGVG
360 370 380 390 400
SVLVFTPNIF AMFLALGFLE ESGYLPRAAF VMDRIMEKFK LSGRAFMSLI
410 420 430 440 450
LGFGCNVPSI MATRAIDDPR ERLVTILITP FISCSARLPV YLLILRIFFP
460 470 480 490 500
ESSAAMLFII YSLSILITLL SSVVINWLFY RGRTSPLILE LPRYRMPTLK
510 520 530 540 550
NLYIYTWNRG KHFLKKAGTI IFVSAILIWV LSYFPAAGDI ENSFSAMIGK
560 570 580 590 600
SLEWIFKPFG YSWKIVTSLF YGAVAKEVVV STMSMLYGFE EETFLGAKEA
610 620 630 640 650
LSAEMDPVSA IAFLIFVMAY IPCFATIATI YSETGSLKWT LFSIGYSLSI
660
AYVLSLIVFY VGKLVVMLI
Length:669
Mass (Da):75,140
Last modified:November 1, 1999 - v1
Checksum:i4B040B460C19A760
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35145.1.
CP004077 Genomic DNA. Translation: AGL48974.1.
PIRiD72423.
RefSeqiNP_227867.1. NC_000853.1.
WP_004082534.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD35145; AAD35145; TM_0051.
AGL48974; AGL48974; Tmari_0048.
GeneIDi896875.
KEGGitma:TM0051.
tmm:Tmari_0048.
tmw:THMA_0047.
PATRICi23934942. VBITheMar51294_0049.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35145.1.
CP004077 Genomic DNA. Translation: AGL48974.1.
PIRiD72423.
RefSeqiNP_227867.1. NC_000853.1.
WP_004082534.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3A1SX-ray1.50A/B17-269[»]
3A1TX-ray1.80A17-269[»]
3A1UX-ray1.80A/B17-269[»]
3A1VX-ray2.40A/B17-269[»]
3A1WX-ray1.90A17-179[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM0051.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD35145; AAD35145; TM_0051.
AGL48974; AGL48974; Tmari_0048.
GeneIDi896875.
KEGGitma:TM0051.
tmm:Tmari_0048.
tmw:THMA_0047.
PATRICi23934942. VBITheMar51294_0049.

Phylogenomic databases

eggNOGiENOG4105CE1. Bacteria.
COG0370. LUCA.
KOiK04759.
OMAiIWYLSSY.

Family and domain databases

CDDicd01879. FeoB. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR003373. Fe2_transport_prot-B.
IPR011640. Fe2_transport_prot_B_C.
IPR030389. G_FEOB_dom.
IPR011642. Gate_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PANTHERiPTHR11649:SF37. PTHR11649:SF37. 2 hits.
PfamiPF07664. FeoB_C. 1 hit.
PF02421. FeoB_N. 1 hit.
PF07670. Gate. 2 hits.
[Graphical view]
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00437. feoB. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51711. G_FEOB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9WXQ8_THEMA
AccessioniPrimary (citable) accession number: Q9WXQ8
Secondary accession number(s): G4FGW6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: November 2, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.