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Q9WX76 (RRF_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosome-recycling factor
Short name=RRF
Alternative name(s):
Ribosome-releasing factor
Gene names
Name:frr
Ordered Locus Names:TTHA0858
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus ›

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another By similarity. HAMAP-Rule MF_00040

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the RRF family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslational termination

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Ribosome-recycling factor HAMAP-Rule MF_00040
PRO_0000167567

Secondary structure

1 ......................... 185
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9WX76 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: F3135ABF7F813328

FASTA18520,994
        10         20         30         40         50         60 
MTLKELYAET RSHMQKSLEV LEHNLAGLRT GRANPALLLH LKVEYYGAHV PLNQIATVTA 

        70         80         90        100        110        120 
PDPRTLVVQS WDQNALKAIE KAIRDSDLGL NPSNKGDALY INIPPLTEER RKDLVRAVRQ 

       130        140        150        160        170        180 
YAEEGRVAIR NIRREALDKL KKLAKELHLS EDETKRAEAE IQKITDEFIA KADQLAEKKE 


QEILG

« Hide

References

« Hide 'large scale' references
[1]"Amber mutations in ribosome recycling factors of Escherichia coli and Thermus thermophilus: evidence for C-terminal modulator element."
Fujiwara T., Ito K., Nakayashiki T., Nakamura Y.
FEBS Lett. 447:297-302(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
[3]"Crystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switch."
Toyoda T., Tin O.F., Ito K., Fujiwara T., Kumasaka T., Yamamoto M., Garber M.B., Nakamura Y.
RNA 6:1432-1444(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS).
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB016498 Genomic DNA. Translation: BAA76865.1.
AP008226 Genomic DNA. Translation: BAD70681.1.
RefSeqYP_144124.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1EH1X-ray2.60A1-185[»]
2QBEX-ray3.3061-185[»]
2QBGX-ray3.3061-185[»]
2QBIX-ray4.0061-185[»]
2QBKX-ray4.0061-185[»]
2V46X-ray3.80Y1-185[»]
2V48X-ray3.80Y1-185[»]
2Z4LX-ray4.4561-185[»]
2Z4NX-ray4.4561-185[»]
3J0Delectron microscopy11.10J1-185[»]
3J0Eelectron microscopy9.90G1-185[»]
ProteinModelPortalQ9WX76.
SMRQ9WX76. Positions 1-185.
ModBaseSearch...

Protein-protein interaction databases

STRING300852.TTHA0858.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD70681; BAD70681; BAD70681.
GeneID3170111.
KEGGttj:TTHA0858.
PATRIC23956698. VBITheThe93045_0852.

Phylogenomic databases

eggNOGCOG0233.
HOGENOMHOG000040143.
KOK02838.
OMAVMVEYYG.
ProtClustDBPRK00083.

Family and domain databases

HAMAPMF_00040. RRF.
InterProIPR002661. Ribosome_recyc_fac.
IPR023584. Ribosome_recyc_fac_dom.
[Graphical view]
PANTHERPTHR20982. PTHR20982. 1 hit.
PfamPF01765. RRF. 1 hit.
[Graphical view]
SUPFAMSSF55194. Ribosome_recyc_fac. 1 hit.
TIGRFAMsTIGR00496. frr. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ9WX76.

Entry information

Entry nameRRF_THET8
AccessionPrimary (citable) accession number: Q9WX76
Secondary accession number(s): Q5SJZ4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: May 1, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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