Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9WX76

- RRF_THET8

UniProt

Q9WX76 - RRF_THET8

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ribosome-recycling factor

Gene

frr

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.UniRule annotation

GO - Biological processi

  1. translational termination Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-890-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome-recycling factorUniRule annotation
Short name:
RRFUniRule annotation
Alternative name(s):
Ribosome-releasing factorUniRule annotation
Gene namesi
Name:frrUniRule annotation
Ordered Locus Names:TTHA0858
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000532: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 185185Ribosome-recycling factorPRO_0000167567Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA0858.

Structurei

Secondary structure

1
185
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 2624Combined sources
Helixi36 – 383Combined sources
Beta strandi42 – 454Combined sources
Beta strandi48 – 514Combined sources
Helixi52 – 543Combined sources
Beta strandi57 – 593Combined sources
Beta strandi65 – 695Combined sources
Helixi73 – 8311Combined sources
Beta strandi84 – 863Combined sources
Beta strandi92 – 954Combined sources
Beta strandi98 – 1025Combined sources
Helixi110 – 14738Combined sources
Helixi151 – 18333Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1EH1X-ray2.60A1-185[»]
2QBEX-ray3.3061-185[»]
2QBGX-ray3.3061-185[»]
2QBIX-ray4.0061-185[»]
2QBKX-ray4.0061-185[»]
2V46X-ray3.80Y1-185[»]
2V48X-ray3.80Y1-185[»]
2Z4LX-ray4.4561-185[»]
2Z4NX-ray4.4561-185[»]
3J0Delectron microscopy11.10J1-185[»]
3J0Eelectron microscopy9.90G1-185[»]
ProteinModelPortaliQ9WX76.
SMRiQ9WX76. Positions 1-185.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9WX76.

Family & Domainsi

Sequence similaritiesi

Belongs to the RRF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0233.
HOGENOMiHOG000040143.
KOiK02838.
OMAiEKECTED.
OrthoDBiEOG6SV5F9.
PhylomeDBiQ9WX76.

Family and domain databases

HAMAPiMF_00040. RRF.
InterProiIPR002661. Ribosome_recyc_fac.
IPR023584. Ribosome_recyc_fac_dom.
[Graphical view]
PANTHERiPTHR20982. PTHR20982. 1 hit.
PfamiPF01765. RRF. 1 hit.
[Graphical view]
SUPFAMiSSF55194. SSF55194. 1 hit.
TIGRFAMsiTIGR00496. frr. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9WX76-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLKELYAET RSHMQKSLEV LEHNLAGLRT GRANPALLLH LKVEYYGAHV
60 70 80 90 100
PLNQIATVTA PDPRTLVVQS WDQNALKAIE KAIRDSDLGL NPSNKGDALY
110 120 130 140 150
INIPPLTEER RKDLVRAVRQ YAEEGRVAIR NIRREALDKL KKLAKELHLS
160 170 180
EDETKRAEAE IQKITDEFIA KADQLAEKKE QEILG
Length:185
Mass (Da):20,994
Last modified:November 1, 1999 - v1
Checksum:iF3135ABF7F813328
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB016498 Genomic DNA. Translation: BAA76865.1.
AP008226 Genomic DNA. Translation: BAD70681.1.
RefSeqiWP_011172951.1. NC_006461.1.
YP_144124.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70681; BAD70681; BAD70681.
GeneIDi3170111.
KEGGittj:TTHA0858.
PATRICi23956698. VBITheThe93045_0852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB016498 Genomic DNA. Translation: BAA76865.1 .
AP008226 Genomic DNA. Translation: BAD70681.1 .
RefSeqi WP_011172951.1. NC_006461.1.
YP_144124.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1EH1 X-ray 2.60 A 1-185 [» ]
2QBE X-ray 3.30 6 1-185 [» ]
2QBG X-ray 3.30 6 1-185 [» ]
2QBI X-ray 4.00 6 1-185 [» ]
2QBK X-ray 4.00 6 1-185 [» ]
2V46 X-ray 3.80 Y 1-185 [» ]
2V48 X-ray 3.80 Y 1-185 [» ]
2Z4L X-ray 4.45 6 1-185 [» ]
2Z4N X-ray 4.45 6 1-185 [» ]
3J0D electron microscopy 11.10 J 1-185 [» ]
3J0E electron microscopy 9.90 G 1-185 [» ]
ProteinModelPortali Q9WX76.
SMRi Q9WX76. Positions 1-185.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 300852.TTHA0858.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD70681 ; BAD70681 ; BAD70681 .
GeneIDi 3170111.
KEGGi ttj:TTHA0858.
PATRICi 23956698. VBITheThe93045_0852.

Phylogenomic databases

eggNOGi COG0233.
HOGENOMi HOG000040143.
KOi K02838.
OMAi EKECTED.
OrthoDBi EOG6SV5F9.
PhylomeDBi Q9WX76.

Enzyme and pathway databases

BioCyci TTHE300852:GH8R-890-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q9WX76.

Family and domain databases

HAMAPi MF_00040. RRF.
InterProi IPR002661. Ribosome_recyc_fac.
IPR023584. Ribosome_recyc_fac_dom.
[Graphical view ]
PANTHERi PTHR20982. PTHR20982. 1 hit.
Pfami PF01765. RRF. 1 hit.
[Graphical view ]
SUPFAMi SSF55194. SSF55194. 1 hit.
TIGRFAMsi TIGR00496. frr. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Amber mutations in ribosome recycling factors of Escherichia coli and Thermus thermophilus: evidence for C-terminal modulator element."
    Fujiwara T., Ito K., Nakayashiki T., Nakamura Y.
    FEBS Lett. 447:297-302(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete genome sequence of Thermus thermophilus HB8."
    Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
    Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB8 / ATCC 27634 / DSM 579.
  3. "Crystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switch."
    Toyoda T., Tin O.F., Ito K., Fujiwara T., Kumasaka T., Yamamoto M., Garber M.B., Nakamura Y.
    RNA 6:1432-1444(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS).

Entry informationi

Entry nameiRRF_THET8
AccessioniPrimary (citable) accession number: Q9WX76
Secondary accession number(s): Q5SJZ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: November 26, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3