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Q9WX29

- SYR_STRCO

UniProt

Q9WX29 - SYR_STRCO

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:SCO3304
ORF Names:SCE68.02
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 586586Arginine--tRNA ligasePRO_0000151616Add
BLAST

Proteomic databases

PRIDEiQ9WX29.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi100226.SCO3304.

Structurei

3D structure databases

ProteinModelPortaliQ9WX29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi127 – 13711"HIGH" regionAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247212.
InParanoidiQ9WX29.
KOiK01887.
OMAiYVKFHDE.
OrthoDBiEOG6JB13C.
PhylomeDBiQ9WX29.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9WX29-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASVTSLSDS VQQHLASALT ATRPEAAGAD PLLRRSDRAD YQANGILALA
60 70 80 90 100
KKTKANPREL AAEVVARITT GDELIEDVEV SGPGFLNITV ADRAITANLA
110 120 130 140 150
ARLADGERLG VPLKQDAGTT VVDYAQPNVA KEMHVGHLRS AVIGDALRSM
160 170 180 190 200
LDFTGEKTIG RHHIGDWGTQ FGMLIQYLFE HPGELAPAGD IDGEQAMSNL
210 220 230 240 250
NRVYKASRAV FDTDEEFKER ARRRVVALQS GDKETLDLWQ QFVDESKVYF
260 270 280 290 300
YSVFEKLDME IRDEEIVGES AYNDGMPETA RLLEEMGVAV RSEGALVVFF
310 320 330 340 350
DEIRGKDDQP VPLIVQKADG GFGYAASDLT AIRNRVQDLH ATTLLYVVDV
360 370 380 390 400
RQSLHFRMVF ETARRAGWLG DEVTAHNMGY GTVLGADGKP FKTRAGETVR
410 420 430 440 450
LEDLLDEAVQ RAAEVVREKA RDLTEDEIQE RAAQVGIGAV KYADLSTSPN
460 470 480 490 500
RDYKFDLDQM VSLNGDTSVY LQYAYARIQS ILRKAGEVRP AAHPELALHE
510 520 530 540 550
AERALGLHLD AFGPTVFEAA AEYAPHKLAA YLYQLASLYT TFYDKCPVLK
560 570 580
AETPEQVENR LFLCDLTART LHRGMALLGI RTPERL
Length:586
Mass (Da):64,704
Last modified:November 1, 1999 - v1
Checksum:i6EA6F2158A7CB91D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939116 Genomic DNA. Translation: CAB45338.1.
PIRiT36252.
RefSeqiNP_627514.1. NC_003888.3.
WP_011028896.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB45338; CAB45338; CAB45338.
GeneIDi1098738.
KEGGisco:SCO3304.
PATRICi23736354. VBIStrCoe124346_3365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939116 Genomic DNA. Translation: CAB45338.1 .
PIRi T36252.
RefSeqi NP_627514.1. NC_003888.3.
WP_011028896.1. NC_003888.3.

3D structure databases

ProteinModelPortali Q9WX29.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 100226.SCO3304.

Proteomic databases

PRIDEi Q9WX29.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB45338 ; CAB45338 ; CAB45338 .
GeneIDi 1098738.
KEGGi sco:SCO3304.
PATRICi 23736354. VBIStrCoe124346_3365.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247212.
InParanoidi Q9WX29.
KOi K01887.
OMAi YVKFHDE.
OrthoDBi EOG6JB13C.
PhylomeDBi Q9WX29.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiSYR_STRCO
AccessioniPrimary (citable) accession number: Q9WX29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3