Q9WWW2 (ALKJ_PSEPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Alcohol dehydrogenase [acceptor]
EC=1.1.99.-

Gene names

Name:

alkJ

Organism

Pseudomonas putida (Arthrobacter siderocapsulatus)

Taxonomic identifier

303 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	552 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts aliphatic medium-chain-length alcohols into aldehydes. May be linked to the electron transfer chain.
Catalytic activity	Alcohol + acceptor = aldehyde + reduced acceptor.
Cofactor	FAD By similarity.
Subcellular location	Cell inner membrane By similarity.
Sequence similarities	Belongs to the GMC oxidoreductase family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	alcohol metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: InterPro flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 552	552	Alcohol dehydrogenase [acceptor]		PRO_0000205579
Regions
	Nucleotide binding	3 – 32	30	FAD Potential
Sites
	Active site	469	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9WWW2 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: D8419AEEE61D74C3	FASTA	552	60,709
	10 20 30 40 50 60 MYDYIIVGAG SAGCVLANRL SADPSKRVCL LEAGPRDTNP LIHMPLGIAL LSNSKKLNWA 70 80 90 100 110 120 FQTAPQQHLN ERSLFWPRGK TLGGSSSINA MVYIRGHEED YQAWEQAGGE YWGWKRAFAL 130 140 150 160 170 180 FKKLEHNQRF DKSNYHGTDG ELAVSDLKDL NPLSKSFVQA GMEAKISFNG DFNGAHQEGV 190 200 210 220 230 240 GFYQVTQKHG QRWSSARAFL HDVIDRPNLD IITEAHATKV LFEDRKAVGV SYIQKNMHQQ 250 260 270 280 290 300 VKTTDSGEVI LSLGAVNTPQ LLMLSGVGAA AELKEHGIAL VHDLPEVGKN LQDHLDITLM 310 320 330 340 350 360 CAANSRTPIG VAFSFIPRGL VGLFSYIFKR KGFLTSNVAE SGGFVKSSPE RDRPNLQFHF 370 380 390 400 410 420 LPTYLKDHGR KIAVGYGYTL HICDLLPKSR GRIGLKSANP MDDPLIDPNY LSDPEDIKTM 430 440 450 460 470 480 IAGIKIGRAI FDAPSMAKHF KREIVPGPAV TSDDEIVADI RSRAETIYHP VGTCRMGKDP 490 500 510 520 530 540 ASVVDPCLQV RGLRNIRVVD ASIMPNLVAG NTNAPTIMIA ENAAEIIVRK VDMASLDASI 550 GFTRQNLEPE LL

References

[1]

"Analysis of Pseudomonas putida alkane degradation gene clusters and flanking insertion sequences: evolution and regulation of the alk-genes." Van Beilen J.B., Panke S., Lucchini S., Franchini A.G., Roethlisberger M., Witholt B. Microbiology 147:1621-1630(2001) [PubMed: 11390693] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: P1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ233397 Genomic DNA. Translation: CAB51051.1.
3D structure databases
ProteinModelPortal	Q9WWW2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALKJ_PSEPU

Accession

Primary (citable) accession number: Q9WWW2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 16, 2004
Last sequence update:	November 1, 1999
Last modified:	October 19, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program