##gff-version 3
Q9WVJ9	UniProtKB	Signal peptide	1	27	.	.	.	Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17324935;Dbxref=PMID:17324935	
Q9WVJ9	UniProtKB	Chain	28	443	.	.	.	ID=PRO_0000007576;Note=EGF-containing fibulin-like extracellular matrix protein 2	
Q9WVJ9	UniProtKB	Domain	36	81	.	.	.	Note=EGF-like 1%3B atypical;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Domain	123	163	.	.	.	Note=EGF-like 2%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Domain	164	202	.	.	.	Note=EGF-like 3%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Domain	203	242	.	.	.	Note=EGF-like 4%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Domain	243	282	.	.	.	Note=EGF-like 5%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Domain	283	328	.	.	.	Note=EGF-like 6%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Region	91	117	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9WVJ9	UniProtKB	Site	87	88	.	.	.	Note=Cleavage%3B by ELANE;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O95967	
Q9WVJ9	UniProtKB	Site	90	91	.	.	.	Note=Cleavage%3B by MMP2%2C MMP3%2C MMP7%2C MMP9%2C MMP12;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O95967	
Q9WVJ9	UniProtKB	Site	92	93	.	.	.	Note=Cleavage;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O95967	
Q9WVJ9	UniProtKB	Modified residue	28	28	.	.	.	Note=Pyrrolidone carboxylic acid;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17324935;Dbxref=PMID:17324935	
Q9WVJ9	UniProtKB	Glycosylation	198	198	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9WVJ9	UniProtKB	Glycosylation	394	394	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9WVJ9	UniProtKB	Disulfide bond	58	121	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	65	80	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	71	109	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	127	140	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	134	149	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	151	162	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	168	177	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	173	186	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	188	201	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	207	217	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	213	226	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	228	241	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	247	258	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	254	267	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	269	281	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	287	300	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	294	309	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Disulfide bond	315	327	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076	
Q9WVJ9	UniProtKB	Mutagenesis	57	57	.	.	.	Note=Knockin mutant mice are viable and survive into adulthood. Mice display abnormalities in multiple organ systems%2C including loose skin%2C bent forelimb%2C aortic aneurysm%2C tortuous artery%2C and pulmonary emphysema. In addition to elastic fiber abnormalities in the skin and large arteries%2C collagen fibrils are irregularly shaped%2C with many large fibrils in the dermis. Mice have large artery stiffness and systolic hypertension. Reduces protein secretion. E->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:26178373,ECO:0000269|PubMed:28508064;Dbxref=PMID:26178373,PMID:28508064	
Q9WVJ9	UniProtKB	Sequence conflict	30	30	.	.	.	Note=P->T;Ontology_term=ECO:0000305;evidence=ECO:0000305