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Q9WV03

- FA50A_MOUSE

UniProt

Q9WV03 - FA50A_MOUSE

Protein

Protein FAM50A

Gene

Fam50a

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Nov 1999)
      Previous versions | rss
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    Functioni

    May be a DNA-binding protein or transcriptional factor.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein FAM50A
    Alternative name(s):
    Protein XAP-5
    Gene namesi
    Name:Fam50a
    Synonyms:D0HXS9928E, Xap5
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:1351626. Fam50a.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 339338Protein FAM50APRO_0000068285Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ9WV03.
    PaxDbiQ9WV03.
    PRIDEiQ9WV03.

    PTM databases

    PhosphoSiteiQ9WV03.

    Expressioni

    Tissue specificityi

    Widely expressed in embryonic and adult tissues.

    Gene expression databases

    ArrayExpressiQ9WV03.
    BgeeiQ9WV03.
    CleanExiMM_D0HXS9928E.
    GenevestigatoriQ9WV03.

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi152 – 1554Nuclear localization signalSequence Analysis

    Sequence similaritiesi

    Belongs to the FAM50 family.Curated

    Phylogenomic databases

    eggNOGiNOG252249.
    GeneTreeiENSGT00390000004735.
    HOGENOMiHOG000283611.
    HOVERGENiHBG000678.
    InParanoidiQ9WV03.
    KOiK13119.
    OMAiVMADQLM.
    OrthoDBiEOG7CZK6H.
    PhylomeDBiQ9WV03.
    TreeFamiTF314738.

    Family and domain databases

    InterProiIPR007005. XAP5.
    [Graphical view]
    PANTHERiPTHR12722. PTHR12722. 1 hit.
    PfamiPF04921. XAP5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9WV03-1 [UniParc]FASTAAdd to Basket

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    MAQYKGAASE AGRAMHLMKK REKQREQMEQ MKQRIAEENI MKSNIDKKFS    50
    AHYDAVEAEL KSSTVGLVTL NDMKAKQEAL VKEREKQLAK KEQSKELQLK 100
    LEKLREKERK KEAKRKISSL SFTLEEEEEG VEEEEEMAMY EEELEREEIT 150
    TKKKKLGKNP DVDTSFLPDR DREEEENRLR EELRQEWEAK QEKIKSEEIE 200
    ITFSYWDGSG HRRTVKMKKG NTMQQFLQKA LEILRKDFSE LRSAGVEQLM 250
    YIKEDLIIPH HHSFYDFIVT KARGKSGPLF NFDVHDDVRL LSDATVEKDE 300
    SHAGKVVLRS WYEKNKHIFP ASRWEPYDPE KKWDKYTIR 339
    Length:339
    Mass (Da):40,252
    Last modified:November 1, 1999 - v1
    Checksum:iB7E700854B06F771
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti46 – 461D → Y in BAB25651. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y18505 mRNA. Translation: CAB46282.1.
    AK008402 mRNA. Translation: BAB25651.1.
    CCDSiCCDS41021.1.
    RefSeqiNP_613073.2. NM_138607.3.
    UniGeneiMm.4370.

    Genome annotation databases

    EnsembliENSMUST00000114160; ENSMUSP00000109797; ENSMUSG00000001962.
    GeneIDi108160.
    KEGGimmu:108160.
    UCSCiuc009ton.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y18505 mRNA. Translation: CAB46282.1 .
    AK008402 mRNA. Translation: BAB25651.1 .
    CCDSi CCDS41021.1.
    RefSeqi NP_613073.2. NM_138607.3.
    UniGenei Mm.4370.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q9WV03.

    Proteomic databases

    MaxQBi Q9WV03.
    PaxDbi Q9WV03.
    PRIDEi Q9WV03.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000114160 ; ENSMUSP00000109797 ; ENSMUSG00000001962 .
    GeneIDi 108160.
    KEGGi mmu:108160.
    UCSCi uc009ton.2. mouse.

    Organism-specific databases

    CTDi 9130.
    MGIi MGI:1351626. Fam50a.

    Phylogenomic databases

    eggNOGi NOG252249.
    GeneTreei ENSGT00390000004735.
    HOGENOMi HOG000283611.
    HOVERGENi HBG000678.
    InParanoidi Q9WV03.
    KOi K13119.
    OMAi VMADQLM.
    OrthoDBi EOG7CZK6H.
    PhylomeDBi Q9WV03.
    TreeFami TF314738.

    Miscellaneous databases

    NextBioi 360194.
    PROi Q9WV03.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9WV03.
    Bgeei Q9WV03.
    CleanExi MM_D0HXS9928E.
    Genevestigatori Q9WV03.

    Family and domain databases

    InterProi IPR007005. XAP5.
    [Graphical view ]
    PANTHERi PTHR12722. PTHR12722. 1 hit.
    Pfami PF04921. XAP5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis."
      Sedlack Z., Muenstermann E., Dhorne-Pollet S., Otto C., Bock D., Schuetz G., Poustka A.
      Genomics 61:125-132(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Small intestine.

    Entry informationi

    Entry nameiFA50A_MOUSE
    AccessioniPrimary (citable) accession number: Q9WV03
    Secondary accession number(s): Q9D866
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2003
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3