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Protein

Protein FAM50A

Gene

Fam50a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be a DNA-binding protein or transcriptional factor.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM50A
Alternative name(s):
Protein XAP-5
Gene namesi
Name:Fam50a
Synonyms:D0HXS9928E, Xap5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1351626. Fam50a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000682852 – 339Protein FAM50AAdd BLAST338

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Cross-linki100Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

EPDiQ9WV03.
MaxQBiQ9WV03.
PaxDbiQ9WV03.
PeptideAtlasiQ9WV03.
PRIDEiQ9WV03.

PTM databases

iPTMnetiQ9WV03.
PhosphoSitePlusiQ9WV03.

Expressioni

Tissue specificityi

Widely expressed in embryonic and adult tissues.

Gene expression databases

BgeeiENSMUSG00000001962.
CleanExiMM_D0HXS9928E.
ExpressionAtlasiQ9WV03. baseline and differential.
GenevisibleiQ9WV03. MM.

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi152 – 155Nuclear localization signalSequence analysis4

Sequence similaritiesi

Belongs to the FAM50 family.Curated

Phylogenomic databases

eggNOGiKOG2894. Eukaryota.
ENOG410XNXM. LUCA.
GeneTreeiENSGT00390000004735.
HOGENOMiHOG000283611.
HOVERGENiHBG000678.
InParanoidiQ9WV03.
KOiK13119.
OMAiYQRNKHI.
OrthoDBiEOG091G0KZY.
PhylomeDBiQ9WV03.
TreeFamiTF314738.

Family and domain databases

InterProiView protein in InterPro
IPR007005. XAP5.
PANTHERiPTHR12722. PTHR12722. 1 hit.
PfamiView protein in Pfam
PF04921. XAP5. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9WV03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQYKGAASE AGRAMHLMKK REKQREQMEQ MKQRIAEENI MKSNIDKKFS
60 70 80 90 100
AHYDAVEAEL KSSTVGLVTL NDMKAKQEAL VKEREKQLAK KEQSKELQLK
110 120 130 140 150
LEKLREKERK KEAKRKISSL SFTLEEEEEG VEEEEEMAMY EEELEREEIT
160 170 180 190 200
TKKKKLGKNP DVDTSFLPDR DREEEENRLR EELRQEWEAK QEKIKSEEIE
210 220 230 240 250
ITFSYWDGSG HRRTVKMKKG NTMQQFLQKA LEILRKDFSE LRSAGVEQLM
260 270 280 290 300
YIKEDLIIPH HHSFYDFIVT KARGKSGPLF NFDVHDDVRL LSDATVEKDE
310 320 330
SHAGKVVLRS WYEKNKHIFP ASRWEPYDPE KKWDKYTIR
Length:339
Mass (Da):40,252
Last modified:November 1, 1999 - v1
Checksum:iB7E700854B06F771
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti46D → Y in BAB25651 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y18505 mRNA. Translation: CAB46282.1.
AK008402 mRNA. Translation: BAB25651.1.
CCDSiCCDS41021.1.
RefSeqiNP_613073.2. NM_138607.3.
UniGeneiMm.4370.

Genome annotation databases

EnsembliENSMUST00000114160; ENSMUSP00000109797; ENSMUSG00000001962.
GeneIDi108160.
KEGGimmu:108160.
UCSCiuc009ton.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiFA50A_MOUSE
AccessioniPrimary (citable) accession number: Q9WV03
Secondary accession number(s): Q9D866
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: November 1, 1999
Last modified: August 30, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families