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Q9WV03 (FA50A_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein FAM50A
Alternative name(s):
Protein XAP-5
Gene names
Name:Fam50a
Synonyms:D0HXS9928E, Xap5
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be a DNA-binding protein or transcriptional factor.

Subcellular location

Nucleus Potential.

Tissue specificity

Widely expressed in embryonic and adult tissues.

Sequence similarities

Belongs to the FAM50 family.

Ontologies

Keywords
   Cellular componentNucleus
   PTMAcetylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 339338Protein FAM50A
PRO_0000068285

Regions

Motif152 – 1554Nuclear localization signal Potential

Amino acid modifications

Modified residue21N-acetylalanine By similarity

Experimental info

Sequence conflict461D → Y in BAB25651. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9WV03 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: B7E700854B06F771

FASTA33940,252
        10         20         30         40         50         60 
MAQYKGAASE AGRAMHLMKK REKQREQMEQ MKQRIAEENI MKSNIDKKFS AHYDAVEAEL 

        70         80         90        100        110        120 
KSSTVGLVTL NDMKAKQEAL VKEREKQLAK KEQSKELQLK LEKLREKERK KEAKRKISSL 

       130        140        150        160        170        180 
SFTLEEEEEG VEEEEEMAMY EEELEREEIT TKKKKLGKNP DVDTSFLPDR DREEEENRLR 

       190        200        210        220        230        240 
EELRQEWEAK QEKIKSEEIE ITFSYWDGSG HRRTVKMKKG NTMQQFLQKA LEILRKDFSE 

       250        260        270        280        290        300 
LRSAGVEQLM YIKEDLIIPH HHSFYDFIVT KARGKSGPLF NFDVHDDVRL LSDATVEKDE 

       310        320        330 
SHAGKVVLRS WYEKNKHIFP ASRWEPYDPE KKWDKYTIR 

« Hide

References

« Hide 'large scale' references
[1]"Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis."
Sedlack Z., Muenstermann E., Dhorne-Pollet S., Otto C., Bock D., Schuetz G., Poustka A.
Genomics 61:125-132(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Small intestine.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y18505 mRNA. Translation: CAB46282.1.
AK008402 mRNA. Translation: BAB25651.1.
CCDSCCDS41021.1.
RefSeqNP_613073.2. NM_138607.3.
UniGeneMm.4370.

3D structure databases

ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ9WV03.

Proteomic databases

MaxQBQ9WV03.
PaxDbQ9WV03.
PRIDEQ9WV03.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000114160; ENSMUSP00000109797; ENSMUSG00000001962.
GeneID108160.
KEGGmmu:108160.
UCSCuc009ton.2. mouse.

Organism-specific databases

CTD9130.
MGIMGI:1351626. Fam50a.

Phylogenomic databases

eggNOGNOG252249.
GeneTreeENSGT00390000004735.
HOGENOMHOG000283611.
HOVERGENHBG000678.
InParanoidQ9WV03.
KOK13119.
OMAVMADQLM.
OrthoDBEOG7CZK6H.
PhylomeDBQ9WV03.
TreeFamTF314738.

Gene expression databases

ArrayExpressQ9WV03.
BgeeQ9WV03.
CleanExMM_D0HXS9928E.
GenevestigatorQ9WV03.

Family and domain databases

InterProIPR007005. XAP5.
[Graphical view]
PANTHERPTHR12722. PTHR12722. 1 hit.
PfamPF04921. XAP5. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio360194.
PROQ9WV03.
SOURCESearch...

Entry information

Entry nameFA50A_MOUSE
AccessionPrimary (citable) accession number: Q9WV03
Secondary accession number(s): Q9D866
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: November 1, 1999
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot