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Protein

C-C motif chemokine

Gene

Ccl17

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • chemokine activity Source: MGI
  • cytokine activity Source: MGI

GO - Biological processi

  • cellular defense response Source: MGI
  • chemotaxis Source: MGI
  • immune response Source: InterPro
  • negative regulation of myoblast differentiation Source: MGI
  • signal transduction Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

CytokineUniRule annotationSAAS annotation

Keywords - Biological processi

ChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-C motif chemokineUniRule annotation
Gene namesi
Name:Ccl17Imported
Synonyms:ABCD-2Imported, TARCImported
ORF Names:mCG_12286Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1329039. Ccl17.

Subcellular locationi

  • Secreted UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_500845251824 – 93C-C motif chemokineUniRule annotationAdd BLAST70

Expressioni

Gene expression databases

BgeeiENSMUSG00000031780.

Interactioni

GO - Molecular functioni

  • chemokine activity Source: MGI
  • cytokine activity Source: MGI

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034232.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 88SCYInterPro annotationAdd BLAST59

Sequence similaritiesi

Belongs to the intercrine beta (chemokine CC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J0QF. Eukaryota.
ENOG41113EM. LUCA.
HOVERGENiHBG098492.
KOiK05514.

Family and domain databases

InterProiIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9WUZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLQMLLLA ALLLGTFLQH ARAARATNVG RECCLDYFKG AIPIRKLVSW
60 70 80 90
YKTSVECSRD AIVFLTVQGK LICADPKDKH VKKAIRLVKN PRP
Length:93
Mass (Da):10,467
Last modified:November 1, 1999 - v1
Checksum:i6EFCD4FDEBEECCCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF125571 mRNA. Translation: AAD56601.1.
AF125572 mRNA. Translation: AAD56602.1.
BC028505 mRNA. Translation: AAH28505.1.
AK007663 mRNA. Translation: BAB25171.1.
AJ242587 mRNA. Translation: CAB45256.1.
CH466525 Genomic DNA. Translation: EDL11145.1.
RefSeqiNP_035462.2. NM_011332.3.
UniGeneiMm.41988.

Genome annotation databases

GeneIDi20295.
KEGGimmu:20295.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF125571 mRNA. Translation: AAD56601.1.
AF125572 mRNA. Translation: AAD56602.1.
BC028505 mRNA. Translation: AAH28505.1.
AK007663 mRNA. Translation: BAB25171.1.
AJ242587 mRNA. Translation: CAB45256.1.
CH466525 Genomic DNA. Translation: EDL11145.1.
RefSeqiNP_035462.2. NM_011332.3.
UniGeneiMm.41988.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034232.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi20295.
KEGGimmu:20295.

Organism-specific databases

CTDi6361.
MGIiMGI:1329039. Ccl17.

Phylogenomic databases

eggNOGiENOG410J0QF. Eukaryota.
ENOG41113EM. LUCA.
HOVERGENiHBG098492.
KOiK05514.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031780.

Family and domain databases

InterProiIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9WUZ6_MOUSE
AccessioniPrimary (citable) accession number: Q9WUZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: November 30, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.