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Protein

C-C motif chemokine

Gene

Ccl17

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • CCR4 chemokine receptor binding Source: MGI
  • chemokine activity Source: MGI
  • cytokine activity Source: MGI

GO - Biological processi

  • cellular defense response Source: MGI
  • chemotaxis Source: MGI
  • immune response Source: InterPro
  • negative regulation of myoblast differentiation Source: MGI
  • signal transduction Source: MGI

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-C motif chemokineUniRule annotation
Gene namesi
Name:Ccl17Imported
Synonyms:ABCD-2Imported, TARCImported
ORF Names:mCG_12286Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1329039 Ccl17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_501502019124 – 93C-C motif chemokineUniRule annotationAdd BLAST70

Interactioni

GO - Molecular functioni

  • CCR4 chemokine receptor binding Source: MGI
  • chemokine activity Source: MGI
  • cytokine activity Source: MGI

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 88SCYInterPro annotationAdd BLAST59

Sequence similaritiesi

Belongs to the intercrine beta (chemokine CC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J0QF Eukaryota
ENOG41113EM LUCA
HOVERGENiHBG098492
KOiK21083

Family and domain databases

InterProiView protein in InterPro
IPR000827 Chemokine_CC_CS
IPR001811 Chemokine_IL8-like_dom
IPR036048 Interleukin_8-like_sf
PfamiView protein in Pfam
PF00048 IL8, 1 hit
SMARTiView protein in SMART
SM00199 SCY, 1 hit
SUPFAMiSSF54117 SSF54117, 1 hit
PROSITEiView protein in PROSITE
PS00472 SMALL_CYTOKINES_CC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9WUZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLQMLLLA ALLLGTFLQH ARAARATNVG RECCLDYFKG AIPIRKLVSW
60 70 80 90
YKTSVECSRD AIVFLTVQGK LICADPKDKH VKKAIRLVKN PRP
Length:93
Mass (Da):10,467
Last modified:November 1, 1999 - v1
Checksum:i6EFCD4FDEBEECCCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF125571 mRNA Translation: AAD56601.1
AF125572 mRNA Translation: AAD56602.1
BC028505 mRNA Translation: AAH28505.1
AK007663 mRNA Translation: BAB25171.1
AJ242587 mRNA Translation: CAB45256.1
CH466525 Genomic DNA Translation: EDL11145.1
RefSeqiNP_035462.2, NM_011332.3
UniGeneiMm.41988

Genome annotation databases

GeneIDi20295
KEGGimmu:20295

Similar proteinsi

Entry informationi

Entry nameiQ9WUZ6_MOUSE
AccessioniPrimary (citable) accession number: Q9WUZ6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: June 20, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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