Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9WUD6 (WNT8B_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein Wnt-8b
Gene names
Name:Wnt8b
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length350 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.

Subcellular location

Secretedextracellular spaceextracellular matrix.

Sequence similarities

Belongs to the Wnt family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 350329Protein Wnt-8b
PRO_0000041451

Amino acid modifications

Glycosylation1021N-linked (GlcNAc...) Potential
Glycosylation2581N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9WUD6 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 69CEE7790461597A

FASTA35038,576
        10         20         30         40         50         60 
MFLMKPVCVL LVTCVLHRSH AWSVNNFLMT GPKAYLVYSS SVAAGAQSGI EECKYQFAWD 

        70         80         90        100        110        120 
RWNCPERALQ LSSHGGLRSA NRETAFVHAI SSAGVMYTLT RNCSLGDFDN CGCDDSRNGQ 

       130        140        150        160        170        180 
LGGQGWLWGG CSDNVGFGEA ISKQFVDALE TGQDARAAMN LHNNEAGRKA VKGTMKRTCK 

       190        200        210        220        230        240 
CHGVSGSCTT QTCWLQLPEF REVGAHLKEK YHAALKVDLL QGAGNSAAGR GAIADTFRSI 

       250        260        270        280        290        300 
STRELVHLED SPDYCLENKT LGLLGTEGRE CLRRGRALGR WERRSCRRLC GDCGLAVEER 

       310        320        330        340        350 
RAETVSSCNC KFHWCCAVRC EQCRRRVTKY FCSRAERPPR GAAHKPGKNS 

« Hide

References

[1]"Mouse Wnt8B is expressed in the developing forebrain and maps to chromosome 19."
Richardson M., Redmond D., Watson C.J., Mason J.O.
Mamm. Genome 10:923-925(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: C57BL/6.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF130349 mRNA. Translation: AAD31816.1.
UniGeneMm.88365.

3D structure databases

ProteinModelPortalQ9WUD6.
SMRQ9WUD6. Positions 30-333.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ9WUD6.

Proteomic databases

PRIDEQ9WUD6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:109485. Wnt8b.

Phylogenomic databases

eggNOGNOG277037.
HOVERGENHBG001595.
InParanoidQ9WUD6.
PhylomeDBQ9WUD6.

Gene expression databases

BgeeQ9WUD6.
CleanExMM_WNT8B.
GenevestigatorQ9WUD6.

Family and domain databases

InterProIPR005817. Wnt.
IPR013301. Wnt8.
IPR018161. Wnt_CS.
[Graphical view]
PANTHERPTHR12027. PTHR12027. 1 hit.
PTHR12027:SF6. PTHR12027:SF6. 1 hit.
PfamPF00110. wnt. 1 hit.
[Graphical view]
PRINTSPR01892. WNT8PROTEIN.
PR01349. WNTPROTEIN.
SMARTSM00097. WNT1. 1 hit.
[Graphical view]
PROSITEPS00246. WNT1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ9WUD6.
SOURCESearch...

Entry information

Entry nameWNT8B_MOUSE
AccessionPrimary (citable) accession number: Q9WUD6
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: April 16, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot