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Protein
Submitted name:

GHRH receptor beta GHRHr

Gene

Ghrhr

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
GHRH receptor beta GHRHrImported
Submitted name:
Growth hormone-releasing hormone receptorImported
Gene namesi
Name:GhrhrImported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi2688. Ghrhr.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei131 – 154HelicalSequence analysisAdd BLAST24
Transmembranei207 – 229HelicalSequence analysisAdd BLAST23
Transmembranei241 – 261HelicalSequence analysisAdd BLAST21
Transmembranei281 – 309HelicalSequence analysisAdd BLAST29
Transmembranei330 – 348HelicalSequence analysisAdd BLAST19
Transmembranei360 – 379HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501084845623 – 439Sequence analysisAdd BLAST417

Expressioni

Gene expression databases

BgeeiENSRNOG00000011808.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 116G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST77
Domaini129 – 380G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST252

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118800.
HOGENOMiHOG000008249.
HOVERGENiHBG008318.

Family and domain databases

Gene3Di4.10.1240.10. 1 hit.
InterProiView protein in InterPro
IPR017981. GPCR_2-like.
IPR001879. GPCR_2_extracellular_dom.
IPR003288. GPCR_2_GHRH_rcpt.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
PANTHERiPTHR12011:SF404. PTHR12011:SF404. 1 hit.
PfamiView protein in Pfam
PF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
PRINTSiPR01352. GHRHRECEPTOR.
PR00249. GPCRSECRETIN.
SMARTiView protein in SMART
SM00008. HormR. 1 hit.
SUPFAMiSSF111418. SSF111418. 1 hit.
PROSITEiView protein in PROSITE
PS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9WU99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSLLWATWV LCLLNLWGVA LGHLHLECDF ITQLRDDELA CLQAAEGTNN
60 70 80 90 100
SSMGCPGTWD GLLCWPPTGS GQWVSLPCPE FFSHFGSDPG AVKRDCTITG
110 120 130 140 150
WSDPFPPYPV ACPVPLELLT EEKSYFSTVK IIYTTGHSIS IVALCVAIAI
160 170 180 190 200
LVALRRLHCP RNYIHTQLFA TFILKASAVF LKDAAVFQGD STDHCSMSTI
210 220 230 240 250
LCKVSVAVSH FATMTNFSWL LAEAVYLSCL LASTSPRSKP AFWWLVLAGW
260 270 280 290 300
GLPVLCTGTW VGCKLAFEDT ACWDLDDSSP YWWIIKGPIV LSVGVNFGLF
310 320 330 340 350
LNIICILLRK LGPAQGGLHT RAQYWRLSKS TLLLIPLFGI HYIIFNFLPD
360 370 380 390 400
SAGLGIRLPL ELGLGSFQGF VVAVLYCFLN QEVRTEISRK WYGHDPELLP
410 420 430
ARRTCTEWTT PPRSRVKVPV YQPPTFSVPV CPHLFFLPI
Length:439
Mass (Da):48,764
Last modified:November 1, 1999 - v1
Checksum:iF1BB2C9A855D24ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128116 Genomic DNA. No translation available.
AF122055 mRNA. Translation: AAD26335.1.
UniGeneiRn.10936.

Genome annotation databases

EnsembliENSRNOT00000084855; ENSRNOP00000071248; ENSRNOG00000011808.

Similar proteinsi

Entry informationi

Entry nameiQ9WU99_RAT
AccessioniPrimary (citable) accession number: Q9WU99
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: August 30, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported