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Protein

Olfactory receptor

Gene

Olfr545

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionUniRule annotationSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr545Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:3030379. Olfr545.

Subcellular locationi

  • Cell membrane UniRule annotationSAAS annotation; Multi-pass membrane protein UniRule annotationSAAS annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei29 – 5123HelicalUniRule annotationAdd
BLAST
Transmembranei63 – 8927HelicalUniRule annotationAdd
BLAST
Transmembranei101 – 12424HelicalUniRule annotationAdd
BLAST
Transmembranei144 – 16724HelicalUniRule annotationAdd
BLAST
Transmembranei241 – 25919HelicalUniRule annotationAdd
BLAST
Transmembranei279 – 29820HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052396.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 296252G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IHPU. Eukaryota.
ENOG410YES3. LUCA.
GeneTreeiENSGT00840000129702.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
KOiK04257.
OMAiDRRWILA.
OrthoDBiEOG754HPV.
TreeFamiTF343312.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9WU94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGWSNGTYN ESYTSFLLMG FPGMQEARAL LVLPFLSLYL VILFTNALVI
60 70 80 90 100
HTVASQRSLH QPMYLLIALL LAVNICAATT VLPPMLFSFS TRFNRISLPR
110 120 130 140 150
CLGQMFCIYF LVSMDCNILL VMALDRYVAI CYPLRYPEIV TGQLLAGLVV
160 170 180 190 200
LAVTRSTSIV APVVVLASRV RFCRSDVIRH FACEHMALMK LSCGDISLNK
210 220 230 240 250
TAGLIIRTFN RVLDMLLLGT SYSRIIHAAF RISSGGARSK ALNTCGSHLL
260 270 280 290 300
VIFTVYSSTM SSSIVYRVAR TASQDVHNLL SAFYLLLPCL VNPIIYGART
310
KEIRQHLVRS FLSAGP
Length:316
Mass (Da):35,033
Last modified:November 1, 1999 - v1
Checksum:i8BABF38098B4C499
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102535 Genomic DNA. No translation available.
AF121980 Genomic DNA. Translation: AAD27600.1.
BC106987 mRNA. Translation: AAI06988.1.
BC128265 mRNA. Translation: AAI28266.1.
BC128266 mRNA. Translation: AAI28267.1.
AY073253 Genomic DNA. Translation: AAL60916.1.
AY317658 Genomic DNA. Translation: AAP71039.1.
RefSeqiNP_667051.1. NM_146840.1.
UniGeneiMm.377714.

Genome annotation databases

EnsembliENSMUST00000058750; ENSMUSP00000052396; ENSMUSG00000044824.
GeneIDi258837.
KEGGimmu:258837.
UCSCiuc009irt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102535 Genomic DNA. No translation available.
AF121980 Genomic DNA. Translation: AAD27600.1.
BC106987 mRNA. Translation: AAI06988.1.
BC128265 mRNA. Translation: AAI28266.1.
BC128266 mRNA. Translation: AAI28267.1.
AY073253 Genomic DNA. Translation: AAL60916.1.
AY317658 Genomic DNA. Translation: AAP71039.1.
RefSeqiNP_667051.1. NM_146840.1.
UniGeneiMm.377714.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052396.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000058750; ENSMUSP00000052396; ENSMUSG00000044824.
GeneIDi258837.
KEGGimmu:258837.
UCSCiuc009irt.1. mouse.

Organism-specific databases

CTDi258837.
MGIiMGI:3030379. Olfr545.

Phylogenomic databases

eggNOGiENOG410IHPU. Eukaryota.
ENOG410YES3. LUCA.
GeneTreeiENSGT00840000129702.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
KOiK04257.
OMAiDRRWILA.
OrthoDBiEOG754HPV.
TreeFamiTF343312.

Miscellaneous databases

NextBioi390893.
SOURCEiSearch...

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Combinatorial receptor codes for odors."
    Malnic B., Hirono J., Sato T., Buck L.B.
    Cell 96:713-723(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
  2. "Different evolutionary processes shaped the mouse and human olfactory receptor gene families."
    Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J.
    Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "The olfactory receptor gene superfamily of the mouse."
    Zhang X., Firestein S.
    Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Adams M.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  5. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
    Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
    Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  6. Sanders K.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  9. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ9WU94_MOUSE
AccessioniPrimary (citable) accession number: Q9WU94
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: May 11, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.