Q9WTS1 (Q9WTS1_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Egfr EMBL BAA76391.1

Gene names

Name:	Egfr RGD 2543
Synonyms:	egfr EMBL BAA76391.1

Organism

Rattus norvegicus (Rat) EMBL BAA76391.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	28 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	activation of MAPKK activity Inferred from mutant phenotype PubMed 14551192. Source: RGD alkanesulfonate metabolic process Inferred from expression pattern PubMed 21251948. Source: RGD astrocyte activation Inferred from mutant phenotype PubMed 16837601. Source: RGD cell proliferation Inferred from electronic annotation. Source: Compara cell-cell adhesion Inferred from electronic annotation. Source: Compara cellular response to dexamethasone stimulus Inferred from expression pattern PubMed 17585012. Source: RGD cellular response to drug Inferred from expression pattern PubMed 21276422PubMed 21389970. Source: RGD cellular response to growth factor stimulus Inferred from expression pattern PubMed 3495539. Source: RGD cellular response to mechanical stimulus Inferred from expression pattern PubMed 20927110. Source: RGD cerebral cortex cell migration Inferred from electronic annotation. Source: Compara circadian rhythm Inferred from expression pattern PubMed 12454858. Source: RGD digestive tract morphogenesis Inferred from electronic annotation. Source: Compara diterpenoid metabolic process Inferred from expression pattern PubMed 21448670. Source: RGD embryonic placenta development Inferred from electronic annotation. Source: Compara hair follicle development Inferred from electronic annotation. Source: Compara hydrogen peroxide metabolic process Inferred from expression pattern PubMed 21258655. Source: RGD intracellular protein kinase cascade Inferred from direct assay PubMed 12107054. Source: RGD liver development Inferred from expression pattern PubMed 12454858. Source: RGD lung development Inferred from expression pattern PubMed 20118217. Source: RGD magnesium ion homeostasis Inferred from mutant phenotype PubMed 22646904. Source: RGD morphogenesis of an epithelial fold Inferred from electronic annotation. Source: Compara negative regulation of apoptotic process Inferred from mutant phenotype PubMed 16466740. Source: RGD negative regulation of mitotic cell cycle Inferred from mutant phenotype PubMed 14551192. Source: RGD negative regulation of protein catabolic process Inferred from electronic annotation. Source: Compara neuron projection morphogenesis Inferred from mutant phenotype PubMed 16648628. Source: RGD ovulation cycle Inferred from mutant phenotype PubMed 11796513. Source: RGD polysaccharide metabolic process Inferred from expression pattern PubMed 21084063. Source: RGD positive regulation of DNA repair Inferred from electronic annotation. Source: Compara positive regulation of DNA replication Inferred from electronic annotation. Source: Compara positive regulation of MAP kinase activity Inferred from electronic annotation. Source: Compara positive regulation of catenin import into nucleus Inferred from electronic annotation. Source: Compara positive regulation of cell migration Inferred from electronic annotation. Source: Compara positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S Inferred from electronic annotation. Source: Compara positive regulation of epithelial cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of fibroblast proliferation Inferred from electronic annotation. Source: Compara positive regulation of inflammatory response Inferred from mutant phenotype PubMed 22824323. Source: RGD positive regulation of nitric oxide biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of protein kinase B signaling cascade Inferred from electronic annotation. Source: Compara positive regulation of smooth muscle cell proliferation Inferred from mutant phenotype PubMed 15486316. Source: RGD positive regulation of superoxide anion generation Inferred from mutant phenotype PubMed 22966991. Source: RGD positive regulation of synaptic transmission, glutamatergic Inferred from mutant phenotype PubMed 16648628. Source: RGD positive regulation of vasoconstriction Inferred from mutant phenotype PubMed 22966991. Source: RGD positive regulation of vasodilation Inferred from mutant phenotype PubMed 23232926. Source: RGD protein autophosphorylation Inferred from direct assay PubMed 3015391. Source: RGD regulation of nitric-oxide synthase activity Inferred from electronic annotation. Source: Compara regulation of peptidyl-tyrosine phosphorylation Inferred from electronic annotation. Source: Compara response to UV-A Inferred from electronic annotation. Source: Compara response to calcium ion Inferred from mutant phenotype PubMed 15950968. Source: RGD response to cobalamin Inferred from expression pattern PubMed 21185268. Source: RGD response to estradiol stimulus Inferred from expression pattern PubMed 2991264. Source: RGD response to hydroxyisoflavone Inferred from expression pattern PubMed 21254785. Source: RGD response to osmotic stress Inferred from expression pattern PubMed 11208719. Source: RGD response to oxidative stress Inferred from expression pattern PubMed 11208719. Source: RGD salivary gland morphogenesis Inferred from electronic annotation. Source: Compara tongue development Inferred from expression pattern PubMed 10908606. Source: RGD translation Inferred from direct assay PubMed 12107054. Source: RGD
Cellular_component	apical plasma membrane Inferred from direct assay PubMed 15631999. Source: RGD basolateral plasma membrane Inferred from direct assay PubMed 15631999. Source: RGD cell surface Inferred from direct assay PubMed 21349584. Source: RGD endocytic vesicle Inferred from direct assay PubMed 11071913. Source: RGD endosome Inferred from direct assay PubMed 21172338. Source: RGD membrane raft Inferred from electronic annotation. Source: Compara nucleus Inferred from direct assay PubMed 17553674. Source: RGD perinuclear region of cytoplasm Inferred from electronic annotation. Source: Compara
Molecular_function	epidermal growth factor binding Inferred from mutant phenotype PubMed 15486316. Source: RGD epidermal growth factor-activated receptor activity Inferred from direct assay PubMed 11796513. Source: RGD nitric-oxide synthase regulator activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	28	1	EMBL BAA76391.1

Sequences

	Sequence		Length	Mass (Da)
	Q9WTS1 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: B56EAB41A074D15A	FASTA	28	2,855
	10 20 MRPSGTARTK LLLLLAALCA AGGALEEK

References

[1]	"Rat EGFR promoter from NRK cells." Kondoh S.K., Akiyama N. Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB025197 Genomic DNA. Translation: BAA76391.1.
IPI	IPI00212694.
UniGene	Rn.37227.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000006087. Q9WTS1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	RGD:2543. rat.
Organism-specific databases
RGD	2543. Egfr.
Phylogenomic databases
InParanoid	Q9WTS1.
Gene expression databases
ArrayExpress	Q9WTS1.
Genevestigator	Q9WTS1.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

Q9WTS1_RAT

Accession

Primary (citable) accession number: Q9WTS1

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)