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Protein
Submitted name:

T-complex polypeptide 1

Gene

tcp1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

  • Kupffer's vesicle development Source: ZFIN
  • protein folding Source: InterPro

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
T-complex polypeptide 1Imported
Submitted name:
Tcp1 proteinImported
Gene namesi
Name:tcp1Imported
Synonyms:TCP1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990714-24. tcp1.

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000017891.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000104575.

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0360. Eukaryota.
COG0459. LUCA.
HOGENOMiHOG000226729.
HOVERGENiHBG001052.
KOiK09493.

Family and domain databases

CDDicd03335. TCP1_alpha. 1 hit.
Gene3Di1.10.560.10. 2 hits.
InterProiView protein in InterPro
IPR012715. Chap_CCT_alpha.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353:SF145. PTHR11353:SF145. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02340. chap_CCT_alpha. 1 hit.
PROSITEiView protein in PROSITE
PS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9W792-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDSPLSVLG QRTTGESVRS QNVMAAASIA NIVKSSLGPV GLDKMLVDDI
60 70 80 90 100
GDVTITNDGA TILKLLEVEH PAAKVLCELA ELQDKEVGDG TTSVVIIAAE
110 120 130 140 150
LLKSADELVK QKIHPTSIIS GYRLACKEAV RYINENLTIG TDDLGRECLL
160 170 180 190 200
NAAKTSMSSK IIGVDAEFFA NMVVDAAVAV KFVDGKGVAR YPINSVNVLK
210 220 230 240 250
AHGRSQKESF LVNGYALNCT VGSQGMVKRV ANAKIACLDF SLQKTKMKLG
260 270 280 290 300
VQVVINDPEK LDQIRQRESD ITKERVQKIL ASGANVVLTT GGIDDMCLKY
310 320 330 340 350
FVDVGAMAVR RVLKKDLKRI AKATGATVCS SLSNLEGEET FEPSMLGQAE
360 370 380 390 400
EVVQERVCDD ELILIKNTKA RTSASIILRG ANDFMCDEME RSLHDALCVV
410 420 430 440 450
KRVLESKSVV PGGGAVEAAL SIYLENYATS MGSREQLAIA EFARSLLVIP
460 470 480 490 500
KTLAVNAAQD STDLVAKLRA FHNEAQVNPD RKNLKWIGLD LVNGKPRDNK
510 520 530 540 550
QAGVYEPTMV KTKSLKFATE AAITILRIDD LIKLFPDQKE GGPSYQDAVQ

SGSLEG
Length:556
Mass (Da):59,986
Last modified:November 1, 1999 - v1
Checksum:i2644822026CE8960
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF143493 mRNA. Translation: AAD34970.1.
BC066538 mRNA. Translation: AAH66538.1.
RefSeqiNP_571305.1. NM_131230.1.
UniGeneiDr.75910.

Genome annotation databases

GeneIDi30477.
KEGGidre:30477.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF143493 mRNA. Translation: AAD34970.1.
BC066538 mRNA. Translation: AAH66538.1.
RefSeqiNP_571305.1. NM_131230.1.
UniGeneiDr.75910.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000104575.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30477.
KEGGidre:30477.

Organism-specific databases

CTDi6950.
ZFINiZDB-GENE-990714-24. tcp1.

Phylogenomic databases

eggNOGiKOG0360. Eukaryota.
COG0459. LUCA.
HOGENOMiHOG000226729.
HOVERGENiHBG001052.
KOiK09493.

Gene expression databases

BgeeiENSDARG00000017891.

Family and domain databases

CDDicd03335. TCP1_alpha. 1 hit.
Gene3Di1.10.560.10. 2 hits.
InterProiView protein in InterPro
IPR012715. Chap_CCT_alpha.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353:SF145. PTHR11353:SF145. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02340. chap_CCT_alpha. 1 hit.
PROSITEiView protein in PROSITE
PS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9W792_DANRE
AccessioniPrimary (citable) accession number: Q9W792
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: June 7, 2017
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.