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Protein
Submitted name:

DEAD-box RNA helicase

Gene

DDX5

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-GGA-72163. mRNA Splicing - Major Pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD-box RNA helicaseImported
Submitted name:
DEAD-box helicase 5Imported
Gene namesi
Name:DDX5Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 18

PTM / Processingi

Proteomic databases

PaxDbiQ9W744.

Expressioni

Gene expression databases

BgeeiENSGALG00000003532.
ExpressionAtlasiQ9W744. baseline.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000034001.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini82 – 110Q_MOTIFInterPro annotationAdd BLAST29
Domaini113 – 288Helicase ATP-bindingInterPro annotationAdd BLAST176
Domaini316 – 463Helicase C-terminalInterPro annotationAdd BLAST148

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi82 – 110Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0331. Eukaryota.
COG0513. LUCA.
GeneTreeiENSGT00900000140856.
HOGENOMiHOG000268804.
HOVERGENiHBG015893.
KOiK12823.
OrthoDBiEOG091G033A.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR033488. DDX5.
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR012587. P68_rpt.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PANTHERiPTHR24031:SF404. PTHR24031:SF404. 1 hit.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF08061. P68HR. 2 hits.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SM01414. P68HR. 2 hits.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9W744-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGFGAPRFG GSRAGPLSGK KFGNPGEKLT KKKWNLDELP KFEKNFYQEH
60 70 80 90 100
PDVVRRTAQE VEQYRSSKEV TVRGHNCPKP IINFYEANFP ANVMEVIQRQ
110 120 130 140 150
NFTEPTAIQA QGWPVALSGL DMVGVAQTGS GKTLSYLLPA IVHINHQPFL
160 170 180 190 200
ERGDGPICLV LAPTRELAQQ VQQVAAEYSR ACRLKSTCIY GGAPKGPQIR
210 220 230 240 250
DLERGVEICI ATPGRLIDFL EAGKTNLRRC TYLVLDEADR MLDMGFEPQI
260 270 280 290 300
RKIVDQIRPD RQTLMWSATW PKEVRQLAED FLKEYVHINI GALELSANHN
310 320 330 340 350
ILQIVDVCHD VEKDDKLIRL MEEIMSEKEN KTIVFVETKR RCDDLTRKMR
360 370 380 390 400
RDGWPAMGIH GDKSQQERDW VLNEFKHGKA PILIATDVAS RGLDVEDVKF
410 420 430 440 450
VINYDYPNSS EDYIHRIGRT ARSTKTGTAY TFFTPNNIKQ VNDLISVLRE
460 470 480 490 500
ANQAINPKLL QLIEDRGSGR SRGDRRDRYS AGKRGGFSSF RERENFERTY
510 520 530 540 550
GALGKRDFGA KAQNGAYSTQ SFSNGTPFGN GFAAAGMQAG FRAGNPAGAY
560 570 580 590
QNGYDQQYGS NIANMHNGMN QQQYAYPATG AAPMIGYPMP ASYSQ
Length:595
Mass (Da):66,736
Last modified:November 1, 1999 - v1
Checksum:iB98192334B6F6201
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000212 Genomic DNA. No translation available.
AF158370 mRNA. Translation: AAD40318.1.
RefSeqiNP_990158.1. NM_204827.1.
UniGeneiGga.4548.

Genome annotation databases

EnsembliENSGALT00000005586; ENSGALP00000005576; ENSGALG00000003532.
GeneIDi395629.
KEGGigga:395629.

Similar proteinsi

Entry informationi

Entry nameiQ9W744_CHICK
AccessioniPrimary (citable) accession number: Q9W744
Secondary accession number(s): F1NM08
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: October 25, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported