Reviewed,
UniProtKB/Swiss-Prot Q9W6S5 (ALLC_XENLA)
Last modified
February 9, 2010.
Version 52.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Allantoicase EC=3.5.3.4 Alternative name(s): Allantoate amidinohydrolase | ||
| Gene names |
| ||
| Organism | Xenopus laevis (African clawed frog) | ||
| Taxonomic identifier | 8355 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Protein attributes
| Sequence length | 389 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Utilization of purines as secondary nitrogen sources, when primary sources are limiting. Ref.1 |
| Catalytic activity | Allantoate + H2O = (S)-ureidoglycolate + urea. |
| Pathway | |
| Tissue specificity | Abundantly expressed in kidney and liver, but at much lower level is also present in brain, testis, intestine and lung. Ref.1 |
| Sequence similarities | Belongs to the allantoicase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Purine metabolism |
| Molecular function | Hydrolase |
| Gene Ontology (GO) | |
| Biological process | purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | allantoicase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Xenopus allantoicase: molecular cloning, enzymatic activity and developmental expression." Vigetti D., Monetti C., Pollegioni L., Taramelli R., Bernardini G. Arch. Biochem. Biophys. 379:90-96(2000) [PubMed: 10864446] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY. Tissue: Brain, Kidney and Liver. |
| [2] | NIH - Xenopus Gene Collection (XGC) project Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF153230 mRNA. Translation: AAD34169.1. BC060404 mRNA. Translation: AAH60404.1. |
| RefSeq | NP_001083467.1. |
| UniGene | Xl.653 |
3D structure databases | |
| SMR | Q9W6S5. Positions 16-384. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 398942. |
| KEGG | xla:398942. |
Organism-specific databases | |
| Xenbase | XB-FEAT-1002642. allc. |
Phylogenomic databases | |
| HOVERGEN | Q9W6S5. |
Enzyme and pathway databases | |
| BRENDA | 3.5.3.4. 648. |
Family and domain databases | |
| InterPro | IPR005164. Allantoicase. IPR015908. Allantoicase_dom. IPR008979. Galactose-bd-like. [Graphical view] |
| PANTHER | PTHR12045. Allantoicase. 1 hit. |
| Pfam | PF03561. Allantoicase. 2 hits. [Graphical view] |
| PIRSF | PIRSF016516. Allantoicase. 1 hit. |
| TIGRFAMs | TIGR02961. allantoicase. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ALLC_XENLA | ||||||||
| Accession | Primary (citable) accession number: Q9W6S5 Secondary accession number(s): Q6PA96 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Xenopus annotation project | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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