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Protein
Submitted name:

Brivido-3, isoform B

Gene

brv3

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • calcium channel activity Source: FlyBase
  • calcium ion binding Source: InterPro

GO - Biological processi

  • calcium ion transport Source: FlyBase
  • detection of mechanical stimulus Source: GO_Central
  • response to cold Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Brivido-3, isoform BImported
Gene namesi
Name:brv3Imported
ORF Names:CG13762Imported, Dmel_CG13762Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0040333. brv3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 29HelicalSequence analysisAdd BLAST24
Transmembranei41 – 63HelicalSequence analysisAdd BLAST23
Transmembranei129 – 146HelicalSequence analysisAdd BLAST18
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Transmembranei417 – 440HelicalSequence analysisAdd BLAST24
Transmembranei461 – 481HelicalSequence analysisAdd BLAST21
Transmembranei501 – 524HelicalSequence analysisAdd BLAST24
Transmembranei536 – 554HelicalSequence analysisAdd BLAST19
Transmembranei566 – 590HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9W4X5.
PRIDEiQ9W4X5.

Expressioni

Gene expression databases

BgeeiFBgn0040333.
ExpressionAtlasiQ9W4X5. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ9W4X5. 2 interactors.
STRINGi7227.FBpp0289932.

Structurei

3D structure databases

ProteinModelPortaliQ9W4X5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini170 – 595PKD_channelInterPro annotationAdd BLAST426

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IQ5E. Eukaryota.
ENOG410YJE6. LUCA.
GeneTreeiENSGT00700000104221.
InParanoidiQ9W4X5.
OrthoDBiEOG091G03U5.
PhylomeDBiQ9W4X5.

Family and domain databases

InterProiIPR013122. PKD1_2_channel.
IPR003915. PKD_2.
[Graphical view]
PfamiPF08016. PKD_channel. 1 hit.
[Graphical view]
PRINTSiPR01433. POLYCYSTIN2.

Sequencei

Sequence statusi: Complete.

Q9W4X5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVKKTHWAM FAITVGIIIG CMICIAVFAG FQHEDVKFKT MLVSIVIVLI
60 70 80 90 100
FQFLIGDPIK FVILSIDRAL WPPRIYIPPR CDKDEMDEKE ERRDFLKQRL
110 120 130 140 150
INKRANLMLT SRYRNYKLND QYKMIAHDLF IYGPYFLCLM CLVLVTRDQT
160 170 180 190 200
LYHNTRIITD LFMYNHTDYT GLQEVYFLNQ LFDFIESTLV LAFNSNSTES
210 220 230 240 250
GSPGWAHAEQ SVLLGVMRLR QLRVSNPQVG LGPPKFSDTY YMPDWQLPYR
260 270 280 290 300
KLHYSDKYWR IYEPWIPIKM GFEFLDALLM NFDHVGSLNS YPELAGYVSL
310 320 330 340 350
LARSAANSMK VIDYLSENHW LTLNTSAVFI DFTLYNVDVN LFSICTLRVE
360 370 380 390 400
KTPFGGIVPD VQVDSAKLLE NVDQMPYTGL LALLIYVLVF IQFAQTLAVK
410 420 430 440 450
LWYEPHLLKS VWNKLDLFIF MVNVLVVVLV VLRESLVASM MKKVEGASKM
460 470 480 490 500
EFIDFRRPSR MHQLTTITIG FLICITTLRL WRVLQFASVF KLFTRTLYLA
510 520 530 540 550
WSAVASTAIA IVIFLIGFCF AVVTINGNYS SNFNKLVKSM VMCMCYSFGF
560 570 580 590 600
SAQVKPSELF HGGKWLGILC YGVLAFVIIV LLINVFVSLI NDYFTVAKTI
610 620 630 640 650
RDSERENRIT FFEFLVVEFS GVLGRFRKLP CWRRNYVRNG RTVAENVSRK
660 670 680 690 700
LDSMDRQRLM RRRLRQGRHH LTLIRMFLFD EYVEWPQEQQ KQPEAQDPDP
710
NLGPDGSPPQ DKRQDEAEA
Length:719
Mass (Da):83,580
Last modified:November 30, 2010 - v3
Checksum:i27DA7C215F4016AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF45799.3.
RefSeqiNP_570013.3. NM_130657.3.
UniGeneiDm.12236.

Genome annotation databases

EnsemblMetazoaiFBtr0300708; FBpp0289932; FBgn0040333.
GeneIDi31246.
UCSCiCG13762-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF45799.3.
RefSeqiNP_570013.3. NM_130657.3.
UniGeneiDm.12236.

3D structure databases

ProteinModelPortaliQ9W4X5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9W4X5. 2 interactors.
STRINGi7227.FBpp0289932.

Proteomic databases

PaxDbiQ9W4X5.
PRIDEiQ9W4X5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0300708; FBpp0289932; FBgn0040333.
GeneIDi31246.
UCSCiCG13762-RA. d. melanogaster.

Organism-specific databases

CTDi31246.
FlyBaseiFBgn0040333. brv3.

Phylogenomic databases

eggNOGiENOG410IQ5E. Eukaryota.
ENOG410YJE6. LUCA.
GeneTreeiENSGT00700000104221.
InParanoidiQ9W4X5.
OrthoDBiEOG091G03U5.
PhylomeDBiQ9W4X5.

Miscellaneous databases

GenomeRNAii31246.

Gene expression databases

BgeeiFBgn0040333.
ExpressionAtlasiQ9W4X5. baseline.

Family and domain databases

InterProiIPR013122. PKD1_2_channel.
IPR003915. PKD_2.
[Graphical view]
PfamiPF08016. PKD_channel. 1 hit.
[Graphical view]
PRINTSiPR01433. POLYCYSTIN2.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9W4X5_DROME
AccessioniPrimary (citable) accession number: Q9W4X5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: November 30, 2010
Last modified: November 30, 2016
This is version 114 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.