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Protein
Submitted name:

Brivido-3, isoform B

Gene

brv3

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • calcium channel activity Source: FlyBase
  • calcium ion binding Source: InterPro

GO - Biological processi

  • calcium ion transport Source: FlyBase
  • response to cold Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-5620916 VxPx cargo-targeting to cilium

Names & Taxonomyi

Protein namesi
Submitted name:
Brivido-3, isoform BImported
Gene namesi
Name:brv3Imported
Synonyms:CT33244Imported, Dmel\CG13762Imported, EG:BACR7C10.7Imported
ORF Names:CG13762Imported, Dmel_CG13762Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0040333 brv3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 29HelicalSequence analysisAdd BLAST24
Transmembranei41 – 63HelicalSequence analysisAdd BLAST23
Transmembranei129 – 146HelicalSequence analysisAdd BLAST18
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Transmembranei417 – 440HelicalSequence analysisAdd BLAST24
Transmembranei461 – 481HelicalSequence analysisAdd BLAST21
Transmembranei501 – 524HelicalSequence analysisAdd BLAST24
Transmembranei536 – 554HelicalSequence analysisAdd BLAST19
Transmembranei566 – 590HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9W4X5
PRIDEiQ9W4X5

Expressioni

Gene expression databases

BgeeiFBgn0040333
ExpressionAtlasiQ9W4X5 differential

Interactioni

Protein-protein interaction databases

IntActiQ9W4X5, 2 interactors
STRINGi7227.FBpp0289932

Structurei

3D structure databases

ProteinModelPortaliQ9W4X5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini170 – 595PKD_channelInterPro annotationAdd BLAST426

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili86 – 106Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IQ5E Eukaryota
ENOG410YJE6 LUCA
GeneTreeiENSGT00700000104221
InParanoidiQ9W4X5
OrthoDBiEOG091G03U5
PhylomeDBiQ9W4X5

Family and domain databases

InterProiView protein in InterPro
IPR013122 PKD1_2_channel
IPR003915 PKD_2
PfamiView protein in Pfam
PF08016 PKD_channel, 1 hit
PRINTSiPR01433 POLYCYSTIN2

Sequencei

Sequence statusi: Complete.

Q9W4X5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVKKTHWAM FAITVGIIIG CMICIAVFAG FQHEDVKFKT MLVSIVIVLI
60 70 80 90 100
FQFLIGDPIK FVILSIDRAL WPPRIYIPPR CDKDEMDEKE ERRDFLKQRL
110 120 130 140 150
INKRANLMLT SRYRNYKLND QYKMIAHDLF IYGPYFLCLM CLVLVTRDQT
160 170 180 190 200
LYHNTRIITD LFMYNHTDYT GLQEVYFLNQ LFDFIESTLV LAFNSNSTES
210 220 230 240 250
GSPGWAHAEQ SVLLGVMRLR QLRVSNPQVG LGPPKFSDTY YMPDWQLPYR
260 270 280 290 300
KLHYSDKYWR IYEPWIPIKM GFEFLDALLM NFDHVGSLNS YPELAGYVSL
310 320 330 340 350
LARSAANSMK VIDYLSENHW LTLNTSAVFI DFTLYNVDVN LFSICTLRVE
360 370 380 390 400
KTPFGGIVPD VQVDSAKLLE NVDQMPYTGL LALLIYVLVF IQFAQTLAVK
410 420 430 440 450
LWYEPHLLKS VWNKLDLFIF MVNVLVVVLV VLRESLVASM MKKVEGASKM
460 470 480 490 500
EFIDFRRPSR MHQLTTITIG FLICITTLRL WRVLQFASVF KLFTRTLYLA
510 520 530 540 550
WSAVASTAIA IVIFLIGFCF AVVTINGNYS SNFNKLVKSM VMCMCYSFGF
560 570 580 590 600
SAQVKPSELF HGGKWLGILC YGVLAFVIIV LLINVFVSLI NDYFTVAKTI
610 620 630 640 650
RDSERENRIT FFEFLVVEFS GVLGRFRKLP CWRRNYVRNG RTVAENVSRK
660 670 680 690 700
LDSMDRQRLM RRRLRQGRHH LTLIRMFLFD EYVEWPQEQQ KQPEAQDPDP
710
NLGPDGSPPQ DKRQDEAEA
Length:719
Mass (Da):83,580
Last modified:November 30, 2010 - v3
Checksum:i27DA7C215F4016AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF45799.3
RefSeqiNP_570013.3, NM_130657.3
UniGeneiDm.12236

Genome annotation databases

EnsemblMetazoaiFBtr0300708; FBpp0289932; FBgn0040333
GeneIDi31246
UCSCiCG13762-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9W4X5_DROME
AccessioniPrimary (citable) accession number: Q9W4X5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 126 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health