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Protein
Submitted name:

Raptor, isoform B

Gene

raptor

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • autophagy Source: FlyBase
  • axon guidance Source: FlyBase
  • cellular response to DNA damage stimulus Source: FlyBase
  • determination of adult lifespan Source: FlyBase
  • eclosion Source: FlyBase
  • larval midgut cell programmed cell death Source: FlyBase
  • muscle organ development Source: FlyBase
  • negative regulation of synaptic growth at neuromuscular junction Source: FlyBase
  • oogenesis Source: FlyBase
  • positive regulation of multicellular organism growth Source: FlyBase
  • positive regulation of protein phosphorylation Source: FlyBase
  • TOR signaling Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DME-1632852. Macroautophagy.
R-DME-165159. mTOR signalling.
R-DME-166208. mTORC1-mediated signalling.
R-DME-3371571. HSF1-dependent transactivation.
R-DME-380972. Energy dependent regulation of mTOR by LKB1-AMPK.
R-DME-5628897. TP53 Regulates Metabolic Genes.

Names & Taxonomyi

Protein namesi
Submitted name:
Raptor, isoform BImported
Submitted name:
Raptor, isoform CImported
Gene namesi
Name:raptorImported
ORF Names:CG4320Imported, Dmel_CG4320Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0029840. raptor.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0029840.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0305180.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini213 – 366Raptor_NInterPro annotationAdd BLAST154

Phylogenomic databases

eggNOGiKOG1517. Eukaryota.
ENOG410XQKJ. LUCA.
GeneTreeiENSGT00640000091541.
KOiK07204.
OMAiPQDARIS.
OrthoDBiEOG091G00H9.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
2.130.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000357. HEAT.
IPR004083. Raptor.
IPR029347. Raptor_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PANTHERiPTHR12848. PTHR12848. 4 hits.
PfamiPF02985. HEAT. 1 hit.
PF14538. Raptor_N. 1 hit.
[Graphical view]
SMARTiSM01302. Raptor_N. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF50978. SSF50978. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9W437-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSAVRAKSA AAAVGVAVDE SSGSSNGSVA DQEVASSKEA VLSVLIRKRY
60 70 80 90 100
EKYVFAPWDD PIILIMEQLE HIEHCRSAAL GNQVAIGRDP SQDDSLNDLG
110 120 130 140 150
KVISNMRQDQ SLVPIVKHIE QISDIQASNG QELASLGSLR ELIRTIRKEW
160 170 180 190 200
PRDDSIKLRL KEIQILGMPP ARSLCFGERI RDDRCPLSLQ TKRHKERIQA
210 220 230 240 250
MMYERQPWRI RERMKTASVA LVLCLNIGVD PPDVVKIQPC SRLECWIDPS
260 270 280 290 300
SVSPPKAMEL IGSNLQMQYE RWQPRARYKK CNDPTVDDVK KLCTSLRRNA
310 320 330 340 350
KGERILFHYN GHGVPKPTAN GEIWVFNKTF TQYIPLSIFE LITWMSAPSI
360 370 380 390 400
YVYDCSNAGI IINSFQPYAK QHEEELGKAL AAAQQRGGVQ QLVGGSGGAA
410 420 430 440 450
NVAANQVQLT NQMVSYKNCI HLAACAANEI LPMNAQLPAD LFTSCLTTPI
460 470 480 490 500
NIALKWYAMQ EKLGMVPRIQ SELIDKIPGK VNDRRTMMGE LNWIFTAITD
510 520 530 540 550
TIAWNTLPRE LFQRLFRQDL LVASLFRNFL LAERILRSHD CTPVSLPALP
560 570 580 590 600
PCYRHPMWKA WDLVVDLALQ QLPEILDHNA PYRQLPFFEH QLTAFQVWLD
610 620 630 640 650
SESESRTPPE QLPIVLQVLL SQVHRLRALE LLARFLDLGP WAVNLALGVG
660 670 680 690 700
IFPYVLKLLQ SSTRELRPVL VFIWAKILAV DPSCQVDLVK EYKYFLSVLQ
710 720 730 740 750
DTSVSKEHRT LSAFVLSSIV HNFLLGQTSA LQGPLLSICL EQLNDGSWLL
760 770 780 790 800
RQWLAICLGM LWQNFEKARW SGARDLAHEK LYVLLRDSIP EVRAAAVFAL
810 820 830 840 850
GTFISSVTDR SEEQANNIDR IIAITMLETV GEDMSPLVRM ELAAALQWMV
860 870 880 890 900
VLFESQFVAV YLTEHMRGHV SAASFVMCPD PRDLTSSTHS LERHVTIRRG
910 920 930 940 950
ASSSSISNMG GASISSGTGS SSNPLGRSKS GSGSSGGRGA AGAAGGTNSI
960 970 980 990 1000
PFQSIFTKLW LGICNLAQDP FPRVAAIAQE IVEHVRDTAL CPIMAAKEAT
1010 1020 1030 1040 1050
MANASEKCSS LSVSLPPSPN TRVNYLGGGG APGGAGATAE SPPVGAAASG
1060 1070 1080 1090 1100
ASHWAQKLRL SGSGACMGAG DPQTILQRKL RTSSINDETD SGPGYSRGVA
1110 1120 1130 1140 1150
GAGTGLGLPS GPRESTHSAR SSGSESNHYL EPGHSLTPIV LTEFIPWAIS
1160 1170 1180 1190 1200
YFTRPGKERY SSAEGSAEEG RQRFPVDRNS AELRRRRLRF LRNDFVRRHA
1210 1220 1230 1240 1250
GRKHQELIDP YGFDVCVWNR KTQFTPSIVK LLPYEPQIAV AYREKVLVYD
1260 1270 1280 1290 1300
FQYNSVRTYG AESLGGNFTG YSSGYGSGSG SSSSLNGSTP RKSGAHTSGG
1310 1320 1330 1340 1350
GGGGFSAAPF ARVSSIEFIN AQDMALNLVA HEDGVVRVWQ SSPPASSATS
1360 1370 1380 1390 1400
EDTPSKARLV TAWTALGQVN QHNHRQRSVA SGGSIGKGAD ASGLSSAAIG
1410 1420 1430 1440 1450
SGGIVTAWQQ CSQHLVIGGG GCRFIRIWDV ERELKLADIP LGRSETCARV
1460 1470 1480 1490 1500
LSPYLPNMRS DVILAGCDDG SVRLFDKRCA PQDAGISVYR RHSAPILHAS
1510 1520 1530 1540 1550
LRANGLVLVS GCTEGRISVA DMRGSQSSIN PFDVVYEWDA GGDVTAITSH
1560 1570 1580 1590 1600
QLEDTVACGN ASKIVIYSLD GRQQKVLRTN EGFIGPKIGH PTYLYFHPYK
1610 1620
AQLAVGFVDN TVAIYSPTPV L
Length:1,621
Mass (Da):177,182
Last modified:June 26, 2013 - v2
Checksum:i2AD280739C91DF3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46122.2.
AE014298 Genomic DNA. Translation: AHN59395.1.
RefSeqiNP_001284924.1. NM_001297995.1.
NP_572294.2. NM_132066.2.
UniGeneiDm.2949.

Genome annotation databases

EnsemblMetazoaiFBtr0332964; FBpp0305180; FBgn0029840.
FBtr0345895; FBpp0311819; FBgn0029840.
GeneIDi31543.
KEGGidme:Dmel_CG4320.
UCSCiCG4320-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46122.2.
AE014298 Genomic DNA. Translation: AHN59395.1.
RefSeqiNP_001284924.1. NM_001297995.1.
NP_572294.2. NM_132066.2.
UniGeneiDm.2949.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0305180.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0332964; FBpp0305180; FBgn0029840.
FBtr0345895; FBpp0311819; FBgn0029840.
GeneIDi31543.
KEGGidme:Dmel_CG4320.
UCSCiCG4320-RA. d. melanogaster.

Organism-specific databases

CTDi31543.
FlyBaseiFBgn0029840. raptor.

Phylogenomic databases

eggNOGiKOG1517. Eukaryota.
ENOG410XQKJ. LUCA.
GeneTreeiENSGT00640000091541.
KOiK07204.
OMAiPQDARIS.
OrthoDBiEOG091G00H9.

Enzyme and pathway databases

ReactomeiR-DME-1632852. Macroautophagy.
R-DME-165159. mTOR signalling.
R-DME-166208. mTORC1-mediated signalling.
R-DME-3371571. HSF1-dependent transactivation.
R-DME-380972. Energy dependent regulation of mTOR by LKB1-AMPK.
R-DME-5628897. TP53 Regulates Metabolic Genes.

Miscellaneous databases

GenomeRNAii31543.

Gene expression databases

BgeeiFBgn0029840.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
2.130.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000357. HEAT.
IPR004083. Raptor.
IPR029347. Raptor_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PANTHERiPTHR12848. PTHR12848. 4 hits.
PfamiPF02985. HEAT. 1 hit.
PF14538. Raptor_N. 1 hit.
[Graphical view]
SMARTiSM01302. Raptor_N. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF50978. SSF50978. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9W437_DROME
AccessioniPrimary (citable) accession number: Q9W437
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: June 26, 2013
Last modified: November 30, 2016
This is version 140 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.