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Protein
Submitted name:

CG4095

Gene

CG4095-RA

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseImported

Enzyme and pathway databases

ReactomeiR-DME-71403. Citric acid cycle (TCA cycle).

Names & Taxonomyi

Protein namesi
Submitted name:
CG4095Imported (EC:4.2.1.2Imported)
Submitted name:
LP11769pImported
Gene namesi
Name:CG4095-RAImported
ORF Names:CG4095Imported, Dmel_CG4095Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0029890. CG4095.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiFBgn0029890.

Interactioni

Protein-protein interaction databases

IntActiQ9W3X5. 6 interactors.
MINTiMINT-742888.
STRINGi7227.FBpp0070916.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 383Lyase_1InterPro annotationAdd BLAST334
Domaini449 – 500FumaraseC_CInterPro annotationAdd BLAST52

Phylogenomic databases

eggNOGiKOG1317. Eukaryota.
COG0114. LUCA.
GeneTreeiENSGT00390000002779.
KOiK01679.
OMAiRIATIWN.
OrthoDBiEOG091G05UL.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
HAMAPiMF_00743. FumaraseC. 1 hit.
InterProiView protein in InterPro
IPR005677. Fum_hydII.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiView protein in Pfam
PF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00979. fumC_II. 1 hit.
PROSITEiView protein in PROSITE
PS00163. FUMARATE_LYASES. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9W3X5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKQNNGLHL ARRNLWVVCS GLRAKDCDSG GKGGKGKENG KFRTEKDTFG
60 70 80 90 100
ELKVPADKLY GAQTMRSKLN FPIGDIGERM PMPVIQAMGI LKKACAEVNK
110 120 130 140 150
DYGLDGKVSD AVSCACDDVI SGKLYKQGHF PLVIWQTGSG TQTNMNTNEV
160 170 180 190 200
ISNAAIKMMG GELGSKKPVH PNDHVNKSQS SNDTFPTAIH ISVGMELNER
210 220 230 240 250
LVPAVTHLRD ALKSKSDEFK DIIKIGRTHL MDAVPLTLGQ EFSGYTQQLT
260 270 280 290 300
NGLERIKGCL PRVYELALGG TAVGTGLNTR KGFAEKVAKR ISELTCLPFV
310 320 330 340 350
SAPNKFEALA ARDAMVEVHG VLNTIAVSLM KIANDIRLLG SGPRCGLGEL
360 370 380 390 400
MLPENEPGSS IMPGKVNPTQ CESMTMLCAQ VMGNQVAVTI GGSNGHFELN
410 420 430 440 450
VFKPLVVSNV LRSIRLLADG SMTFSKNCVE GLQANKERID KIMNESLMLV
460 470 480 490 500
TALNPHIGYD KAALIAKTAH KNKTTLKEEA LKTGITEEQF KEWVNPKEML

GPK
Length:503
Mass (Da):54,518
Last modified:September 13, 2005 - v2
Checksum:iD659765A17DFF78C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46187.2.
BT122060 mRNA. Translation: ADD71883.1.
RefSeqiNP_727109.2. NM_167082.4.
UniGeneiDm.19451.

Genome annotation databases

EnsemblMetazoaiFBtr0070955; FBpp0070916; FBgn0029890.
GeneIDi31606.
KEGGidme:Dmel_CG4095.
UCSCiCG4095-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46187.2.
BT122060 mRNA. Translation: ADD71883.1.
RefSeqiNP_727109.2. NM_167082.4.
UniGeneiDm.19451.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9W3X5. 6 interactors.
MINTiMINT-742888.
STRINGi7227.FBpp0070916.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0070955; FBpp0070916; FBgn0029890.
GeneIDi31606.
KEGGidme:Dmel_CG4095.
UCSCiCG4095-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0029890. CG4095.

Phylogenomic databases

eggNOGiKOG1317. Eukaryota.
COG0114. LUCA.
GeneTreeiENSGT00390000002779.
KOiK01679.
OMAiRIATIWN.
OrthoDBiEOG091G05UL.

Enzyme and pathway databases

ReactomeiR-DME-71403. Citric acid cycle (TCA cycle).

Miscellaneous databases

GenomeRNAii31606.

Gene expression databases

BgeeiFBgn0029890.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
HAMAPiMF_00743. FumaraseC. 1 hit.
InterProiView protein in InterPro
IPR005677. Fum_hydII.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiView protein in Pfam
PF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00979. fumC_II. 1 hit.
PROSITEiView protein in PROSITE
PS00163. FUMARATE_LYASES. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9W3X5_DROME
AccessioniPrimary (citable) accession number: Q9W3X5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: September 13, 2005
Last modified: June 7, 2017
This is version 152 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.