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Protein

60S ribosomal protein L17

Gene

RpL17

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L17
Gene namesi
Name:RpL17
ORF Names:CG3203
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0029897. RpL17.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: FlyBase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003234121 – 18660S ribosomal protein L17Add BLAST186

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei158Phosphoserine1 Publication1
Modified residuei161Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9W3W8.
PRIDEiQ9W3W8.

PTM databases

iPTMnetiQ9W3W8.

Expressioni

Gene expression databases

BgeeiFBgn0029897.
GenevisibleiQ9W3W8. DM.

Interactioni

Protein-protein interaction databases

BioGridi58099. 19 interactors.
IntActiQ9W3W8. 5 interactors.
MINTiMINT-330499.
STRINGi7227.FBpp0070940.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00CP1-186[»]
ProteinModelPortaliQ9W3W8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3353. Eukaryota.
COG0091. LUCA.
InParanoidiQ9W3W8.
KOiK02880.
OMAiINGWKLQ.
OrthoDBiEOG091G0FOW.
PhylomeDBiQ9W3W8.

Family and domain databases

CDDicd00336. Ribosomal_L22. 1 hit.
InterProiView protein in InterPro
IPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005721. Ribosomal_L22/L17_euk/arc.
PANTHERiPTHR11593. PTHR11593. 1 hit.
PfamiView protein in Pfam
PF00237. Ribosomal_L22. 1 hit.
SUPFAMiSSF54843. SSF54843. 1 hit.
TIGRFAMsiTIGR01038. uL22_arch_euk. 1 hit.
PROSITEiView protein in PROSITE
PS00464. RIBOSOMAL_L22. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9W3W8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRYSRESDN VAKSCKARGP NLRVHFKNTH ETAQAIKRMP LRRAQRYLKA
60 70 80 90 100
VIDQKECVPF RRFNGGVGRC AQAKQWKTTQ GRWPKKSAEF LLQLLRNAEA
110 120 130 140 150
NADCKGLDAD RLVVHHIQVN RAQCLRRRTY RAHGRINPYM SSPCHVEVIL
160 170 180
TEKEELVSKA TDDEPAKKKL SKKKLQRQKE KMLRSE
Length:186
Mass (Da):21,593
Last modified:May 1, 2000 - v1
Checksum:i686083C4AD924544
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46194.1.
AE014298 Genomic DNA. Translation: AAF46195.1.
AE014298 Genomic DNA. Translation: AAN09182.1.
AE014298 Genomic DNA. Translation: AAN09183.1.
AY060845 mRNA. Translation: AAL28393.1.
RefSeqiNP_001284961.1. NM_001298032.1.
NP_572346.1. NM_132118.3.
NP_727118.1. NM_167087.1.
NP_727119.1. NM_167088.2.
NP_727120.1. NM_167089.2.
UniGeneiDm.7261.

Genome annotation databases

EnsemblMetazoaiFBtr0070980; FBpp0070940; FBgn0029897.
FBtr0070981; FBpp0070941; FBgn0029897.
FBtr0070982; FBpp0070942; FBgn0029897.
FBtr0070983; FBpp0070943; FBgn0029897.
FBtr0345292; FBpp0311459; FBgn0029897.
GeneIDi31613.
KEGGidme:Dmel_CG3203.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL17_DROME
AccessioniPrimary (citable) accession number: Q9W3W8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families