Q9W3W0 (Q9W3W0_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Inactive EMBL AAF46203.1

Gene names

Name:	iav FlyBase FBgn0001246 FlyBase FBgn0086693
ORF Names:	CG4536 FlyBase FBgn0029904, Dmel_CG4536 EMBL AAF46203.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1123 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	ANK repeat RuleBase RU003321 SAAS SAAS005821 Repeat RuleBase RU003536 Transmembrane RuleBase RU003378
Molecular function	Ionic channel RuleBase RU003378
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	behavioral response to cocaine Non-traceable author statement. Source: FlyBase flight behavior Inferred from mutant phenotype. Source: FlyBase negative gravitaxis Inferred from mutant phenotype. Source: FlyBase response to heat Inferred from mutant phenotype. Source: FlyBase sensory perception of sound Inferred from mutant phenotype. Source: FlyBase thermosensory behavior Inferred from mutant phenotype. Source: FlyBase thermotaxis Inferred from mutant phenotype. Source: FlyBase
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ion channel activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9W3W0 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: AB1E527629744CA4	FASTA	1,123	124,673
	10 20 30 40 50 60 MKFLLKKCLR KKAPEMKPGA ILDAVISQSS ATACKCLLYK LADYKRGGDL IDAINSGGLI 70 80 90 100 110 120 AVEQLIREQF GVFMYNDGKG QVINRAEFLR WKYRDHTEVT IPIEASLSIH DPLGKWEDHK 130 140 150 160 170 180 ACWQMQYRGA LGESLLHVLI ICDSKVHTKL ARVLLRVFPN LALDVMEGEE YLGASALHLS 190 200 210 220 230 240 IAYSNNELVA DLIEAGADIH QRAIGSFFLP RDQQRANPAK STDYEGLAYM GEYPLAWAAC 250 260 270 280 290 300 CANESVYNLL VDCGSDPDAQ DSFGNMILHM VVVCDKLDMF GYALRHPKTP AKNGIVNQTG 310 320 330 340 350 360 LTPLTLACKL GRAEVFREML ELSAREFWRY SNITCSGYPL NALDTLLPDG RTNWNSALFI 370 380 390 400 410 420 ILNGTKPEHL DMLDGGIIQR LLEEKWKTFA QNQFLKRLLI LSTHLLCLSV SVYLRPAHDG 430 440 450 460 470 480 EAEDEDSEGS DASAAALLDI QSDEGDSGGG DYNAQTVARY CAEFATLVGV LSYVIFQQGD 490 500 510 520 530 540 EIKNQGLSAF LKQLSHAPAK AIFLFSNLLI LACIPFRLIG DTDTEEAILI FAVPGSWFLL 550 560 570 580 590 600 MFFAGAIRLT GPFVTMIYSM ITGDMFTFGI IYCIVLCGFS QAFYFLYKGH PQVQSTMFNT 610 620 630 640 650 660 YTSTWMALFQ TTLGDYNYPD LNQTTYPNLS KTVFVIFMIF VPILLLNMLI AMMGNTYVTV 670 680 690 700 710 720 IEQSEKEWMK QWAKIVVTLE RAVPQADAKG YLEAYSIPLG PSDDSGFEVR GVMVIKSKSK 730 740 750 760 770 780 TRAKQRKGAV SNWKRVGRVT LTALKKRGMT GEEMRRLMWG RASISSPVKV TKQKLKDPYN 790 800 810 820 830 840 LHTDSDFTNA MDMLTFASNP ASSNGVTLRS VTAPPPAPPA PDPFRELIMM SDQRPETHDP 850 860 870 880 890 900 HYFAGLQQLA NKAFDLVEQT MKTQPQAPVA KKVDPLPVAS VAKASPAAPA TQATATAAAA 910 920 930 940 950 960 SDLMAMPLPI SNLSNLFQDP KDIVDPKKLE EFMAMLAEVE TEESDSGGPI LGKLSLAKRT 970 980 990 1000 1010 1020 HNALSKAEIR RDQQGFEGHS HGQFQPMSSV WAPPGLDVDT GFHFDEAVAE EVLTIEQEAE 1030 1040 1050 1060 1070 1080 VETEDGNGGQ DSEDIPTAEE VHATMKQFHL RKCQPAQDEA ARRAKSARVR RRNKVSPEQS 1090 1100 1110 1120 DDPDERSQRG RSAYTRRTQS PPDPLEPWST RELQDINKIL ARK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014298 Genomic DNA. Translation: AAF46203.1.
RefSeq	NP_572353.1. NM_132125.1.
UniGene	Dm.31040.
3D structure databases
ProteinModelPortal	Q9W3W0.
SMR	Q9W3W0. Positions 124-369.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9W3W0.
Proteomic databases
PRIDE	Q9W3W0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0070969; FBpp0070930; FBgn0086693.
GeneID	31621.
KEGG	dme:Dmel_CG4536.
NMPDR	fig|7227.3.peg.16781.
UCSC	CG4536-RA. d. melanogaster.
Organism-specific databases
CTD	31621.
FlyBase	FBgn0086693. iav.
Phylogenomic databases
eggNOG	inNOG08602.
GeneTree	EMGT00050000006235.
InParanoid	Q9W3W0.
OMA	LLMFFAG.
OrthoDB	EOG4FFBGS.
PhylomeDB	Q9W3W0.
Gene expression databases
ArrayExpress	Q9W3W0.
Bgee	Q9W3W0.
Family and domain databases
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR005821. Ion_trans. IPR024862. TRPV_channel. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
PANTHER	PTHR10582. PTHR10582. 1 hit.
Pfam	PF12796. Ank_2. 1 hit. PF00520. Ion_trans. 1 hit. [Graphical view]
SMART	SM00248. ANK. 5 hits. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	774538.

Entry information

Entry name

Q9W3W0_DROME

Accession

Primary (citable) accession number: Q9W3W0

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)