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Protein
Submitted name:

GM14286p

Gene

Pdp

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • [pyruvate dehydrogenase (lipoamide)] phosphatase activity Source: UniProtKB-EC
  • phosphoprotein phosphatase activity Source: FlyBase
  • protein serine/threonine phosphatase activity Source: FlyBase

GO - Biological processi

  • protein dephosphorylation Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

PyruvateImported

Enzyme and pathway databases

ReactomeiR-DME-204174. Regulation of pyruvate dehydrogenase (PDH) complex.

Names & Taxonomyi

Protein namesi
Submitted name:
GM14286pImported
Submitted name:
Pyruvate dehydrogenase phosphatase, isoform AImported (EC:3.1.3.16Imported, EC:3.1.3.43Imported)
Submitted name:
Pyruvate dehydrogenase phosphatase, isoform BImported
Gene namesi
Name:PdpImported
ORF Names:CG12151Imported, Dmel_CG12151Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0029958. Pdp.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: FlyBase
  • mitochondrion Source: FlyBase
  • nucleus Source: FlyBase
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0029958.

Interactioni

Protein-protein interaction databases

MINTiMINT-1597350.
STRINGi7227.FBpp0298274.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 453PPM-type phosphataseInterPro annotationAdd BLAST396

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
GeneTreeiENSGT00390000006874.
KOiK01102.
OMAiFKWSLEL.
OrthoDBiEOG091G05XU.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 5 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9W3Q1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKFVLNDAA SYVRSNVREF SLNALRLLPQ LPQLSPYDVN LVLRENEFVY
60 70 80 90 100
NFPVDGVIRS YETNQLGSNW PCEDSRTEAS FLHRNGFICG IFDGHAGAAC
110 120 130 140 150
GQVVSKRLLR YVSAATLPRQ VLREQMKQGA DSQSFLKCHN DNVDFVSMIK
160 170 180 190 200
PMYEASFLKY VNQLLETPQR DVSSELVNAF LQLDEEISQE ALTSNDVRTM
210 220 230 240 250
NVALSGAVAC LVHIEGLQMH VASTGDCGAV LGVLDPQTQQ WHSKKLNIEH
260 270 280 290 300
NADNMSEVRR ILAEHPKEEH ETVIRNGRLL SQLAPLRAFG DFRYKWSQEI
310 320 330 340 350
MQQKVLPMFG VQAMAPNYYT PPYLTARPDV QQHELGPNDK FLVIASDGLW
360 370 380 390 400
DFLPPSEVVS LVGEHINSKK ILEPMRLPEG DTTLQEISQQ LAERKAGLTR
410 420 430 440 450
KPVDQNAATH LIRHALGGTD YGIEHSKISY YLTLPRDAVR LYRDDITITV
460 470
IYFNSEHIAK LHSDVDQTEV TAPVA
Length:475
Mass (Da):53,551
Last modified:May 1, 2000 - v1
Checksum:i460F5DC4D4FB04DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46270.1.
AY060985 mRNA. Translation: AAL28533.1.
AE014298 Genomic DNA. Translation: AFH07281.1.
RefSeqiNP_001245567.1. NM_001258638.2.
NP_572404.1. NM_132176.4.
UniGeneiDm.96.

Genome annotation databases

EnsemblMetazoaiFBtr0071076; FBpp0071033; FBgn0029958.
FBtr0307273; FBpp0298274; FBgn0029958.
GeneIDi31683.
KEGGidme:Dmel_CG12151.
UCSCiCG12151-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46270.1.
AY060985 mRNA. Translation: AAL28533.1.
AE014298 Genomic DNA. Translation: AFH07281.1.
RefSeqiNP_001245567.1. NM_001258638.2.
NP_572404.1. NM_132176.4.
UniGeneiDm.96.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1597350.
STRINGi7227.FBpp0298274.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0071076; FBpp0071033; FBgn0029958.
FBtr0307273; FBpp0298274; FBgn0029958.
GeneIDi31683.
KEGGidme:Dmel_CG12151.
UCSCiCG12151-RA. d. melanogaster.

Organism-specific databases

CTDi31683.
FlyBaseiFBgn0029958. Pdp.

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
GeneTreeiENSGT00390000006874.
KOiK01102.
OMAiFKWSLEL.
OrthoDBiEOG091G05XU.

Enzyme and pathway databases

ReactomeiR-DME-204174. Regulation of pyruvate dehydrogenase (PDH) complex.

Miscellaneous databases

ChiTaRSiPdp1. fly.
GenomeRNAii31683.

Gene expression databases

BgeeiFBgn0029958.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 5 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9W3Q1_DROME
AccessioniPrimary (citable) accession number: Q9W3Q1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 125 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.