Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Autophagy-related 8a, isoform A

Gene

Atg8a

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • protein kinase binding Source: FlyBase
  • protein tag Source: FlyBase

GO - Biological processi

  • autophagosome assembly Source: GO_Central
  • autophagy Source: FlyBase
  • cellular response to nitrogen starvation Source: GO_Central
  • determination of adult lifespan Source: FlyBase
  • larval midgut cell programmed cell death Source: FlyBase
  • macroautophagy Source: FlyBase
  • mitophagy Source: GO_Central
  • regulation of autophagy Source: FlyBase
  • regulation of protein ubiquitination Source: FlyBase
Complete GO annotation...

Keywords - Biological processi

AutophagyUniRule annotation

Enzyme and pathway databases

ReactomeiR-DME-1632852. Macroautophagy.

Names & Taxonomyi

Protein namesi
Submitted name:
Autophagy-related 8a, isoform AImported
Submitted name:
LD05816pImported
Gene namesi
Name:Atg8aImported
ORF Names:CG32672Imported, Dmel_CG32672Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0052672. Atg8a.

Subcellular locationi

GO - Cellular componenti

  • amphisome Source: FlyBase
  • autolysosome Source: FlyBase
  • autophagosome Source: FlyBase
  • autophagosome lumen Source: FlyBase
  • autophagosome membrane Source: GO_Central
  • cytosol Source: GO_Central
Complete GO annotation...

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi116Phosphatidylethanolamine amidated glycineUniRule annotation1

Keywords - PTMi

LipoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0052672.

Interactioni

GO - Molecular functioni

  • protein kinase binding Source: FlyBase

Protein-protein interaction databases

DIPiDIP-19734N.
MINTiMINT-826708.
STRINGi7227.FBpp0071427.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG8 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1654. Eukaryota.
ENOG4111JAT. LUCA.
GeneTreeiENSGT00390000012937.
OMAiTTMGQLY.
OrthoDBiEOG091G10QX.

Family and domain databases

CDDicd01611. GABARAP. 1 hit.
InterProiIPR004241. Atg8-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10969. PTHR10969. 1 hit.
PfamiPF02991. Atg8. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9W2S2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFQYKEEHA FEKRRAEGDK IRRKYPDRVP VIVEKAPKAR IGDLDKKKYL
60 70 80 90 100
VPSDLTVGQF YFLIRKRIHL RPEDALFFFV NNVIPPTSAT MGSLYQEHHE
110 120
EDYFLYIAYS DENVYGMAKI N
Length:121
Mass (Da):14,392
Last modified:May 1, 2000 - v1
Checksum:i2B99947562A320A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46617.1.
AY122152 mRNA. Translation: AAM52664.1.
RefSeqiNP_727447.1. NM_167245.3.
UniGeneiDm.20907.

Genome annotation databases

EnsemblMetazoaiFBtr0071498; FBpp0071427; FBgn0052672.
GeneIDi32001.
UCSCiCG32672-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF46617.1.
AY122152 mRNA. Translation: AAM52664.1.
RefSeqiNP_727447.1. NM_167245.3.
UniGeneiDm.20907.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-19734N.
MINTiMINT-826708.
STRINGi7227.FBpp0071427.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0071498; FBpp0071427; FBgn0052672.
GeneIDi32001.
UCSCiCG32672-RA. d. melanogaster.

Organism-specific databases

CTDi32001.
FlyBaseiFBgn0052672. Atg8a.

Phylogenomic databases

eggNOGiKOG1654. Eukaryota.
ENOG4111JAT. LUCA.
GeneTreeiENSGT00390000012937.
OMAiTTMGQLY.
OrthoDBiEOG091G10QX.

Enzyme and pathway databases

ReactomeiR-DME-1632852. Macroautophagy.

Miscellaneous databases

GenomeRNAii32001.

Gene expression databases

BgeeiFBgn0052672.

Family and domain databases

CDDicd01611. GABARAP. 1 hit.
InterProiIPR004241. Atg8-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10969. PTHR10969. 1 hit.
PfamiPF02991. Atg8. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9W2S2_DROME
AccessioniPrimary (citable) accession number: Q9W2S2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 129 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.