Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Palmitoyltransferase

Gene

CG10344

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG10344Imported, Dmel_CG10344Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0034729. CG10344.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 40HelicalUniRule annotationAdd BLAST29
Transmembranei46 – 62HelicalUniRule annotationAdd BLAST17
Transmembranei139 – 160HelicalUniRule annotationAdd BLAST22
Transmembranei193 – 218HelicalUniRule annotationAdd BLAST26

GO - Cellular componenti

  • endoplasmic reticulum Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9W251.
PRIDEiQ9W251.

Expressioni

Gene expression databases

BgeeiFBgn0034729.
ExpressionAtlasiQ9W251. differential.
GenevisibleiQ9W251. DM.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0071752.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 220DHHCInterPro annotationAdd BLAST130

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
InParanoidiQ9W251.
KOiK18932.
OMAiHVPIVLR.
OrthoDBiEOG091G0RWR.
PhylomeDBiQ9W251.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9W251-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIRSNPMPS RMVDILCFLI IAVFLPVVFM FEIVVVLPAF HEPGGFFHTF
60 70 80 90 100
TFLMAMFLVF NIKGNMIACM MIDTSVNVKK VEPPSDQLNW RECGECQKLA
110 120 130 140 150
PPRSWHCKAC KVCILKRDHH CIYTGCCIGL RNHRFFMGFI FYLFVGSVYA
160 170 180 190 200
LVYNSIYMWV IHGHIYSNWV TVLKLACPML HLVTGSFWTN MYLVFYSLNI
210 220 230 240 250
LALAYGVLLL AYHVPIVLRG GVSADRTKES KEKYDRGVYQ NLRSVFGNRM
260 270
HLAWLSPLIR SDLPEDGYHW NVPTNKQD
Length:278
Mass (Da):32,167
Last modified:October 1, 2002 - v2
Checksum:iEF9CD3B18D384F33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF46848.2.
RefSeqiNP_611671.1. NM_137827.3.
UniGeneiDm.20177.

Genome annotation databases

EnsemblMetazoaiFBtr0071841; FBpp0071752; FBgn0034729.
GeneIDi37565.
KEGGidme:Dmel_CG10344.
UCSCiCG10344-RB. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9W251_DROME
AccessioniPrimary (citable) accession number: Q9W251
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: July 5, 2017
This is version 129 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported