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Protein
Submitted name:

CG9194

Gene

anon-WO0109301.19

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotation
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-DME-1299344 TWIK-related spinal cord K+ channel (TRESK)
R-DME-5576886 Phase 4 - resting membrane potential

Names & Taxonomyi

Protein namesi
Submitted name:
CG9194Imported
Submitted name:
FI03418pImported
Gene namesi
Name:anon-WO0109301.19Imported
Synonyms:anon-WO0109301.20Imported, anon-WO0109301.21Imported, anon-WO0109301.22Imported, anon-WO0109301.23Imported, anon-WO0109301.24Imported, anon-WO0109301.25Imported, anon-WO0109301.26Imported, anon-WO0109301.27Imported, anon-WO0109301.28Imported, anon-WO0109301.29Imported, anon-WO0109301.3Imported, anon-WO0109301.31Imported, anon-WO0109301.32Imported, anon-WO0109301.33Imported, anon-WO0109301.34Imported, anon-WO0109301.36Imported, anon-WO0109301.37Imported, anon-WO0109301.38Imported, C9194Imported, CG9194-RAImported, Dmel\CG9194Imported
ORF Names:CG9194Imported, Dmel_CG9194Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0035192 CG9194

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei38 – 59HelicalSequence analysisAdd BLAST22
Transmembranei135 – 156HelicalSequence analysisAdd BLAST22
Transmembranei168 – 190HelicalSequence analysisAdd BLAST23
Transmembranei621 – 641HelicalSequence analysisAdd BLAST21
Transmembranei647 – 667HelicalSequence analysisAdd BLAST21
Transmembranei679 – 701HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9W0J0

Expressioni

Gene expression databases

BgeeiFBgn0035192
ExpressionAtlasiQ9W0J0 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ9W0J0, 2 interactors
STRINGi7227.FBpp0072545

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini133 – 189Ion_trans_2InterPro annotationAdd BLAST57
Domaini627 – 705Ion_trans_2InterPro annotationAdd BLAST79

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418 Eukaryota
COG1226 LUCA
GeneTreeiENSGT00700000104522
OMAiISPRTDW
OrthoDBiEOG091G03S1

Family and domain databases

InterProiView protein in InterPro
IPR003280 2pore_dom_K_chnl
IPR013099 K_chnl_dom
PfamiView protein in Pfam
PF07885 Ion_trans_2, 2 hits
PRINTSiPR01333 2POREKCHANEL

Sequencei

Sequence statusi: Complete.

Q9W0J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRRAQSLP AHMLEPAKPQ RGRCVAAICF SWKVLTCIVS HVLLVLLVVS
60 70 80 90 100
YCVGGAYLFQ HLERPHELEV KRDIQNLRVN LTENIWLLSD DAVVLRESDW
110 120 130 140 150
MANVSKHLAN FEKQILTAIK ADGWDGDEDL RKSQWTFAGS LFYSIIVITT
160 170 180 190 200
IGYGHISPRT DWGKVTTIFY AIVGIPLMLI CLSNIGDVMA TSFRFLYWRI
210 220 230 240 250
CCYVCTRTAK RPRNARSRQR SMRSQRHARS QPPPSFRRSM KMTQRSGNDS
260 270 280 290 300
GLGPSMGHAY SDPDLRTMGR GYDDREFGHR SSGGGRNRRQ QQQQHLHHDP
310 320 330 340 350
RQRHTIYGDG YETQTLNRSN RYSSRQRQRD RMRDRHTVER ERYSRSHLDA
360 370 380 390 400
GSIEDFGDMQ PPAKRAASVR SVRSPHNQES SKASRELHRL HSAPGRSRAK
410 420 430 440 450
SVDPRHVSSH YEDVDEDVVR KTPIIPNRYA LDDFGGNRRQ AAPRSQSMPR
460 470 480 490 500
SAHQRQRQKD RERERSPQPP PQSSYRQQHD RRAGSLGRQS SRYGNHLELP
510 520 530 540 550
DYDAPPPGRD HRRDRRGHSQ GRYEDYVEES FDEGSLYGDN NYEDYPPERH
560 570 580 590 600
HSRSREPKRN RRRERAERLP PSPRIMSPMG FPVQRQIRRR PSYDYDDDDS
610 620 630 640 650
MYGDEYGDYG DLLPKDRPVP IWLCVFLVVS YILGGAVLFA YWENWSFLDS
660 670 680 690 700
AYFCFITLTT IGFGDFVPAK GVKDESEQSI AYCSLYLLFG IALLAMSFNL
710 720
VQEEFIANVK EVARRLGILK DDDDEQDED
Length:729
Mass (Da):84,392
Last modified:May 1, 2000 - v1
Checksum:i545F0D5350BE9908
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF47456.1
BT050451 mRNA Translation: ACJ13158.1
RefSeqiNP_612084.1, NM_138240.2
UniGeneiDm.31131

Genome annotation databases

EnsemblMetazoaiFBtr0072651; FBpp0072545; FBgn0035192
GeneIDi38133
KEGGidme:Dmel_CG9194
UCSCiCG9194-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9W0J0_DROME
AccessioniPrimary (citable) accession number: Q9W0J0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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