Unreviewed, UniProtKB/TrEMBL Q9W0H2 (Q9W0H2_DROME)

Names and origin

Protein names

Submitted name:
    CG9153, isoform A EMBL AAF47474.2
    EC=6.3.2.19
Submitted name:
    CG9153, isoform B EMBL AAF47475.2

Gene names

ORF Names:

CG9153 FlyBase FBgn0035207, Dmel_CG9153 EMBL AAF47474.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1058 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. Spearmint SPM000569

Ontologies

Keywords
Biological process	Ubl conjugation pathway Spearmint SPM000569
Domain	Repeat Spearmint SPM000408
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: InterPro ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	ubiquitin-protein ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9W0H2-1 [UniParc]. Last modified October 1, 2002. Version 2. Checksum: 727D2FEBE40A2081	FASTA	1,058	119,015
	10 20 30 40 50 60 MASGKELYCW GSTSHGQLGL GGIEDEQILT PSQIPWTPDT AVQQVACGHR HTLFLTATGK 70 80 90 100 110 120 VYACGSNDYS QLGHDLPTKR PLLIPELQDY VIIQICCGSR HSLALSDWGQ VLSWGDNDCG 130 140 150 160 170 180 QLGHATDKEI VQLPKVVRQL VTKTVVQIAC GNNHSLALTS CGELYSWGSN IYGQLGVNSP 190 200 210 220 230 240 NDLTHCNYPL RLTTLLGIPL AAIACGGNHS FLISKSGAVF GWGRNNCGQL GLNDETNRSY 250 260 270 280 290 300 PTQLKTLRTL GVRFVACGDE FSVFLTNEGG VFTCGAGAYG QLGHGFSSNE MLPRMVMELM 310 320 330 340 350 360 GSTITQVACG NRHTLALVPS RGRVYAFGLG SSGQLGTRST KSLMLPQVVI GPWVSPSGSA 370 380 390 400 410 420 LLQSNDSQVS LVIRQIFSGG DQSIVTTTLF VDKVPPEDFR NYNPKSQILT LTAEVTKQCA 430 440 450 460 470 480 QCKQGLQSDM DLLSSIELIF RSQACWNGSF LLDHDRHFGC SVRNHGLDLK AAQLAFDNLR 490 500 510 520 530 540 AVENESIRQV IWDNITKELV GSLVCSPADV ESMRLYLLLP LYHEFVNSKH YKSLQVPFAN 550 560 570 580 590 600 AIFKLAENPR KVLNKWLAQT PAEYFEHLVQ NFLHVVIHII SFKMGLAAAS PSAERRQQLL 610 620 630 640 650 660 PYNTELEIIL KLMKTLCQIN NERHDRLNYQ IFYWPDLSDY ADVQQEYVKW IMADTARDFN 670 680 690 700 710 720 ICNYSFIFDQ SAKTALLQAD QALQMHSAMA NAATMQAFSF FNYGMPISQF IVLNVTRENL 730 740 750 760 770 780 VQDSLRELQH YSQSDLKKPL KIKFHGEEAE DAGGVRKEFF MLLLKDLLDP KYGMFKEYEQ 790 800 810 820 830 840 SRLLWFADLT FETENMYFLI GVLCGLAIYN FTIINLPFPL ALFKKLLGKP VDLSDLRQLS 850 860 870 880 890 900 PPEANSMQSL LDYQGDDFKE VFDLTFEISR DVFGEAETKC LKPNGNEIAV TLENRQEFVD 910 920 930 940 950 960 LYVDFVFNKS VELHYNAFHK GFMKVCSGRV IHIFQPEELM AVVVGNEDYD WQALQDNCEY 970 980 990 1000 1010 1020 REGYTSVDDT IKWFWEVIHD MSEAEKKSFL LFLTGSDRIP IQGMKALKLT IQPTPDERFL 1030 1040 1050 PVAHTCFNLL DLPRYKTKER LKYKLLQAIQ QTQGFSLV

References

[1]

"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

[2]

"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014296 Genomic DNA. Translation: AAF47474.2. AE014296 Genomic DNA. Translation: AAF47475.2.
RefSeq	NP_612098.2. NP_728591.1.
UniGene	Dm.12435
3D structure databases
HSSP	HSSP built from PDB template 1C4Z based on UniProtKB Q05086.
ModBase	Search...
Genome annotation databases
Ensembl	FBgn0035207. Drosophila melanogaster. [Contig view]
GeneID	38151.
KEGG	dme:Dmel_CG9153.
Organism-specific databases
FlyBase	FBgn0035207. CG9153.
Phylogenomic databases
OMA	Q9W0H2. VPRNIKS.
Gene expression databases
ArrayExpress	Q9W0H2.
Family and domain databases
InterPro	IPR000569. HECT. IPR000408. Reg_chr_condens. IPR009091. Reg_csome_cond/b-lactamase_inh. [Graphical view]
Gene3D	G3DSA:2.130.10.30. Reg_csome_cond/b-lactamase_inh. 1 hit.
Pfam	PF00632. HECT. 1 hit. PF00415. RCC1. 4 hits. [Graphical view]
PRINTS	PR00633. RCCNDNSATION.
SMART	SM00119. HECTc. 1 hit. [Graphical view]
PROSITE	PS50237. HECT. 1 hit. PS00626. RCC1_2. 5 hits. PS50012. RCC1_3. 7 hits. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	807214.

Entry information

Entry name

Q9W0H2_DROME

Accession

Primary (citable) accession number: Q9W0H2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 54 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)