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Protein

Nucleolar MIF4G domain-containing protein 1 homolog

Gene

CG9004

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • neurogenesis Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar MIF4G domain-containing protein 1 homolog
Gene namesi
ORF Names:CG9004
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0035336. CG9004.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 854854Nucleolar MIF4G domain-containing protein 1 homologPRO_0000286825Add
BLAST

Proteomic databases

PaxDbiQ9W020.
PRIDEiQ9W020.

Expressioni

Gene expression databases

BgeeiQ9W020.
GenevisibleiQ9W020. DM.

Interactioni

Protein-protein interaction databases

BioGridi63818. 1 interaction.
MINTiMINT-313743.
STRINGi7227.FBpp0072768.

Structurei

3D structure databases

ProteinModelPortaliQ9W020.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini352 – 553202MIF4GPROSITE-ProRule annotationAdd
BLAST
Domaini650 – 764115MIPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi3 – 235233Lys-richAdd
BLAST

Sequence similaritiesi

Belongs to the CWC22 family.Curated
Contains 1 MI domain.PROSITE-ProRule annotation
Contains 1 MIF4G domain.Curated

Phylogenomic databases

eggNOGiKOG2141. Eukaryota.
ENOG410XNNQ. LUCA.
GeneTreeiENSGT00550000075087.
InParanoidiQ9W020.
KOiK17583.
OMAiACFLEAV.
OrthoDBiEOG7SR4M4.
PhylomeDBiQ9W020.

Family and domain databases

Gene3Di1.25.40.180. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR003891. Initiation_fac_eIF4g_MI.
IPR016021. MIF4-like.
IPR003890. MIF4G-like_typ-3.
[Graphical view]
PfamiPF02847. MA3. 1 hit.
PF02854. MIF4G. 1 hit.
[Graphical view]
SMARTiSM00544. MA3. 1 hit.
SM00543. MIF4G. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS51366. MI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9W020-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKIKKKEAK AKPLTRKEQR KQKSEFKKQN KRLYFAGKTN GTQRVAAAAE
60 70 80 90 100
ALAAQSQLGK NKKKKRSKKP KIINPDEIPK EQLLSGEIDS DDDESIDSDF
110 120 130 140 150
SDAEVDALLP AREKMEVYEP LGKKVKKTTG GAIQRQDEEA VRRKELRQQK
160 170 180 190 200
ELESKSKKQR IKQLRIENEE DDREINKLEK KLKLNKSKDK NRLVRKMFND
210 220 230 240 250
GLDYLLDFVL DDEEEKRKWE EKQERKKKLK EQQEKEEAGM WSDEEEDKED
260 270 280 290 300
RDEPMDNFSE DDSGSEGEDD DEDLTGEEEQ SEEDSEQEEN APKIKEDIYG
310 320 330 340 350
RKRDAEGNIL PDPVELEASA AGQKYIPPHQ RALMAASAGS SEKQAEILAR
360 370 380 390 400
LLKQCKGLLN RLSEANLHKI AAGIEELYMK NSRYNMNETL TKLIQEALLG
410 420 430 440 450
YTRTNERMVQ EHMVLLAYLH AQVGSEIGAH FLQTFVELFD GYVKNIATLE
460 470 480 490 500
VEDKQLNNLV LVLCYMYLFK IYELNLLMEL IGKLSDQLCE KSVECLLLIF
510 520 530 540 550
QSIGFRLRKD DPLAFKTMMQ KVQSQIASAP LELKENPRLR FMVDILNAVK
560 570 580 590 600
NNNMQKLPQY DPELAENLRK RLKAMLKNDR YVVTLNITLE DLLRADKVGK
610 620 630 640 650
WWIVGSAWTG NLDEMGSAKQ KQDKNSSKSA NGGFADQLLE LARKQQMNTA
660 670 680 690 700
ERRNIFCIIM SAADYVDAFE KILHLSLKDQ RAVAYVIIHC ALNEKRANPY
710 720 730 740 750
YAHLALKFCQ FNRKYQLAFQ FASWDRINDI EKLSKPQIRN LASFLQQVIL
760 770 780 790 800
AAGLQLSVLK VVDFMQLDKL SFYFMKEVMV RLLLANDERE IYQTFERVAK
810 820 830 840 850
NTKLQQFKQS VRLFLQHFLL QEEQLDKLKL KDEDRQLLQQ RVDHIDKLLA

YVDL
Length:854
Mass (Da):99,116
Last modified:May 1, 2000 - v1
Checksum:i41A648A2EE918E2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF47640.1.
BT010298 mRNA. Translation: AAQ23616.1.
RefSeqiNP_647717.1. NM_139460.2.
UniGeneiDm.11397.

Genome annotation databases

EnsemblMetazoaiFBtr0072890; FBpp0072768; FBgn0035336.
GeneIDi38303.
KEGGidme:Dmel_CG9004.
UCSCiCG9004-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF47640.1.
BT010298 mRNA. Translation: AAQ23616.1.
RefSeqiNP_647717.1. NM_139460.2.
UniGeneiDm.11397.

3D structure databases

ProteinModelPortaliQ9W020.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi63818. 1 interaction.
MINTiMINT-313743.
STRINGi7227.FBpp0072768.

Proteomic databases

PaxDbiQ9W020.
PRIDEiQ9W020.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0072890; FBpp0072768; FBgn0035336.
GeneIDi38303.
KEGGidme:Dmel_CG9004.
UCSCiCG9004-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0035336. CG9004.

Phylogenomic databases

eggNOGiKOG2141. Eukaryota.
ENOG410XNNQ. LUCA.
GeneTreeiENSGT00550000075087.
InParanoidiQ9W020.
KOiK17583.
OMAiACFLEAV.
OrthoDBiEOG7SR4M4.
PhylomeDBiQ9W020.

Miscellaneous databases

GenomeRNAii38303.
NextBioi807950.
PROiQ9W020.

Gene expression databases

BgeeiQ9W020.
GenevisibleiQ9W020. DM.

Family and domain databases

Gene3Di1.25.40.180. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR003891. Initiation_fac_eIF4g_MI.
IPR016021. MIF4-like.
IPR003890. MIF4G-like_typ-3.
[Graphical view]
PfamiPF02847. MA3. 1 hit.
PF02854. MIF4G. 1 hit.
[Graphical view]
SMARTiSM00544. MA3. 1 hit.
SM00543. MIF4G. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS51366. MI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Berkeley.
    Tissue: Embryo.

Entry informationi

Entry nameiNOM1_DROME
AccessioniPrimary (citable) accession number: Q9W020
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 1, 2000
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.