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Protein
Submitted name:

Myocardin-related transcription factor, isoform D

Gene

Mrtf

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • activating transcription factor binding Source: FlyBase
  • RNA polymerase II transcription coactivator activity Source: FlyBase

GO - Biological processi

  • actin cytoskeleton organization Source: FlyBase
  • border follicle cell migration Source: FlyBase
  • cellular response to hypoxia Source: FlyBase
  • imaginal disc-derived wing morphogenesis Source: FlyBase
  • mesodermal cell migration Source: FlyBase
  • open tracheal system development Source: FlyBase
  • positive regulation of transcription from RNA polymerase II promoter Source: FlyBase
  • regulation of cell division Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-5663220. RHO GTPases Activate Formins.

Names & Taxonomyi

Protein namesi
Submitted name:
Myocardin-related transcription factor, isoform DImported
Submitted name:
Myocardin-related transcription factor, isoform GImported
Gene namesi
Name:MrtfImported
Synonyms:Dmel\CG32296Imported, DMRTFImported, dMRTFImported, dMrtfImported, malImported, MAL-DImported, Mal-DImported, mal-dImported, MRTFImported
ORF Names:CG12188Imported, CG14951Imported, CG32296Imported, Dmel_CG32296Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0052296. Mrtf.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0052296.

Interactioni

GO - Molecular functioni

  • activating transcription factor binding Source: FlyBase

Protein-protein interaction databases

IntActiQ9VZY2. 1 interactor.
MINTiMINT-1657281.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati50 – 75RPELPROSITE-ProRule annotationAdd BLAST26
Repeati94 – 119RPELPROSITE-ProRule annotationAdd BLAST26
Repeati140 – 165RPELPROSITE-ProRule annotationAdd BLAST26
Domaini578 – 612SAPInterPro annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili700 – 741Sequence analysisAdd BLAST42
Coiled coili840 – 890Sequence analysisAdd BLAST51

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IFJX. Eukaryota.
ENOG41101AM. LUCA.
GeneTreeiENSGT00530000063195.
OrthoDBiEOG091G06Z4.

Family and domain databases

Gene3Di1.10.720.30. 1 hit.
2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR004018. RPEL_repeat.
IPR003034. SAP_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
PfamiView protein in Pfam
PF02755. RPEL. 1 hit.
PF02037. SAP. 1 hit.
SMARTiView protein in SMART
SM00707. RPEL. 3 hits.
SM00513. SAP. 1 hit.
SUPFAMiSSF68906. SSF68906. 1 hit.
PROSITEiView protein in PROSITE
PS51073. RPEL. 3 hits.
PS50800. SAP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VZY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEGEQRLHA TFLGSSDDGN NSDCYDARQS PPKAIVDSSP LQPAMDKNKE
60 70 80 90 100
SLKVKLMVRR PHSQLVEQGI IPSLKTSPAI HEQCKQLERA KTSDLLKAKI
110 120 130 140 150
QQRPNREDLE RLHILEEDEC HIDPSLAEKQ RMLKKARLAD QLNSQIQHRP
160 170 180 190 200
GPLELIKKNI LHTEKPIEKI VKEGLVSFKA TSEGLLTRPQ HPHSYVTFDD
210 220 230 240 250
DSLSSESDTR QTPPRLDEAM VATSSSPTDV LQAAAASAGI VTMALTMPTA
260 270 280 290 300
GQLVVTSPQI LPQQQQPKAI VVPAPVPPPP PPPPPLPMAS IIKVKQETAN
310 320 330 340 350
LYEELCQSVT GTTASPVNHL YSPCSLASST STLSPLSSIA SPPPPPMTTT
360 370 380 390 400
RLHLAPVSVK SDAPGKDKNR KKSKSKPVSK ARTIKFHEYK GPPSAAGQKQ
410 420 430 440 450
DQTQPEETSY QLMLEQQNCL LKFLENLNKN QSIIPAPSAP GVMLPAAPGA
460 470 480 490 500
TNNSITVTTK TVPALASQSA PAPAPISLPN TISITSSSGG APLNFGDATM
510 520 530 540 550
LTPTPAATPT PPTLSLIAAP QQQLQLHQQH QQLHQPTPVQ HPPPLPSPAL
560 570 580 590 600
SVSSSIPPSP ATSYAESTTS SITDLARLEK MKVSDLKQHL KRRNLPVSGP
610 620 630 640 650
KPHLIERLKP YLPLEPLDSN VTPAPTSNNS NTTPEVITIS DAMDTSNCGL
660 670 680 690 700
LEQPPPVTML VSDASMEHEQ MDVVQQQMDN THPMTLQTIL PPQPQTATII
710 720 730 740 750
LTNEELLREQ QRKIDELQRQ LQRSQQELQK IRQRQQQQQH QQQQTVTAQV
760 770 780 790 800
VNALPSQQIT LITTTSNGPQ QTLTVMPQQV EKNFPAKVTV KATGGNSNHK
810 820 830 840 850
VNGLQQQGSA AKKPASSNSN SNSNISSSNP PPINQKMVVK QQLEAKIQKQ
860 870 880 890 900
KAAAAAAAQQ QQQQQQQQQQ QQQQQALQQQ QQQQQQQQQV RLLTQKTQTV
910 920 930 940 950
FIPFNNNNHI NNASAKTTTK KSNVPANNTN TTTATMMQAA KPAAVAAAAA
960 970 980 990 1000
SPGNQHHNNL GLLWNEGNQT ILLLGLNDQH MTAHTLGNIS LTATTTTTAA
1010 1020 1030 1040 1050
PPAATPVAAS TIAPPKKILN GHQRTNSLPS IVFPIETKSI ITQQQLQQLQ
1060 1070 1080 1090 1100
QQQQQQQQFQ PVQQPKQQQL NQVDIKPAPA PPPQYEEATK QLAASKAAAL
1110 1120 1130 1140 1150
NGLLPLVKIK EEPVQSPAPS AAPLPQTAPL CKRKTASIKS EQVSDVLDIL
1160 1170 1180 1190 1200
IKQGELPESA ALEPITPLTP LPELSMFNGA TPTTAAGGAS IVPLVPKLET
1210 1220 1230 1240 1250
PVTPVQNLDV AMDTNVQHVG FASNQAPNHV FIESIDMASP LQTDSSAIDA
1260 1270 1280 1290 1300
ESVAKTLDIF LEQHHATPPP STPPKSCHSG SEKPNSPDAK LNHFDEYELL
1310 1320 1330 1340 1350
ELMSQQLEMD MGDDSSGYCH ASAAKSSNNN GNLRRDLNPS LQPSINELLD
1360 1370 1380 1390 1400
ASSPDNVLLN NNTGADVDFD ADSFVAQLSQ HVTGNGNSPG VNCNGSIESS
1410 1420 1430 1440 1450
SSAVNSHFGS HSTPMDCDDF ESTLNSFMQA VTQPQAGQHV EYATSTSMAN
1460 1470 1480 1490
GTGGGMGVDN GTGGAVDAFN ASGDIFDLFN MDDYKMNWAA GDFTV
Length:1,495
Mass (Da):160,890
Last modified:June 26, 2013 - v3
Checksum:iAAC1D1F1E309A0B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: ACL83234.2.
AE014296 Genomic DNA. Translation: AFH04251.1.
RefSeqiNP_001137878.2. NM_001144406.3.
NP_001246580.1. NM_001259651.3.
UniGeneiDm.13305.

Genome annotation databases

EnsemblMetazoaiFBtr0306331; FBpp0297427; FBgn0052296.
FBtr0333444; FBpp0305635; FBgn0052296.
GeneIDi38338.
KEGGidme:Dmel_CG32296.
UCSCiCG32296-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiQ9VZY2_DROME
AccessioniPrimary (citable) accession number: Q9VZY2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: June 26, 2013
Last modified: September 27, 2017
This is version 133 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported