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Protein

60S ribosomal protein L28

Gene

RpL28

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L28
Gene namesi
Name:RpL28
ORF Names:CG12740
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0035422. RpL28.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: FlyBase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001223951 – 14460S ribosomal protein L28Add BLAST144

Proteomic databases

PaxDbiQ9VZS5.
PRIDEiQ9VZS5.

Expressioni

Gene expression databases

BgeeiFBgn0035422.
GenevisibleiQ9VZS5. DM.

Interactioni

Protein-protein interaction databases

BioGridi63893. 4 interactors.
IntActiQ9VZS5. 5 interactors.
MINTiMINT-786006.
STRINGi7227.FBpp0072957.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00Cr1-144[»]
ProteinModelPortaliQ9VZS5.
SMRiQ9VZS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3412. Eukaryota.
ENOG4111T32. LUCA.
InParanoidiQ9VZS5.
KOiK02903.
OMAiWMIIRNN.
OrthoDBiEOG091G0W22.
PhylomeDBiQ9VZS5.

Family and domain databases

InterProiView protein in InterPro
IPR029004. L28e/Mak16.
IPR002672. Ribosomal_L28e.
PANTHERiPTHR10544. PTHR10544. 1 hit.
PfamiView protein in Pfam
PF01778. Ribosomal_L28e. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VZS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATSSHLNWL IIRNNNAFLL KKRDVKKPFS TEPNNLASVS SYRYSGIVHK
60 70 80 90 100
KTLGVVPAAD KKGFTAVLKK GKYAQRPAKN TVRVDFKAGP RRSLKKLKNL
110 120 130 140
LIGSKYRKDL TQAALRRASA VLRSQKPAPV KGKKAEFAKG KKPE
Length:144
Mass (Da):16,029
Last modified:May 1, 2000 - v1
Checksum:i14D5C7866F585113
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAN11546.1.
AE014296 Genomic DNA. Translation: AAN11547.1.
AY071444 mRNA. Translation: AAL49066.1.
RefSeqiNP_001163336.1. NM_001169865.2.
NP_001163337.1. NM_001169866.2.
NP_647791.2. NM_139534.4.
NP_728839.1. NM_168004.2.
NP_728840.1. NM_168005.3.
NP_728841.2. NM_168006.3.
UniGeneiDm.14669.

Genome annotation databases

EnsemblMetazoaiFBtr0073095; FBpp0072957; FBgn0035422.
FBtr0073097; FBpp0072959; FBgn0035422.
FBtr0073098; FBpp0072960; FBgn0035422.
FBtr0302300; FBpp0291506; FBgn0035422.
FBtr0302301; FBpp0291507; FBgn0035422.
FBtr0306567; FBpp0297522; FBgn0035422.
GeneIDi38397.
KEGGidme:Dmel_CG12740.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL28_DROME
AccessioniPrimary (citable) accession number: Q9VZS5
Secondary accession number(s): A4V1E2, Q0E8I7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families