Unreviewed, UniProtKB/TrEMBL Q9VZP5 (Q9VZP5_DROME)

Names and origin

Protein names

Submitted name:
    eIF5B EMBL AAF47774.2

Gene names

Name:	eIF5B EMBL AAF47774.2
ORF Names:	Dmel_CG10840 EMBL AAF47774.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1144 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Ligand	GTP-binding RuleBase RU003312V0 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	DEAD/H-box RNA helicase binding Traceable author statement. Source: FlyBase GTP binding Inferred from electronic annotation. Source: InterPro GTPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VZP5-1 [UniParc]. Last modified October 1, 2002. Version 2. Checksum: A380F75A3762678C	FASTA	1,144	127,203
	10 20 30 40 50 60 MVKAKKGKKE ILTKVEGGSS VDEISDVDSD QLSLNNKQNH ALKGNQAGDD DVKAVTKGVK 70 80 90 100 110 120 KLNVKGKGKA GKNDDSDEEE VVPAKGKASK KSAFELLMDD DEQDEPAAQE SQSEKEEKVV 130 140 150 160 170 180 VSKPQKNEKK GKKAKRKGKD DDDEDLDKVL AELQAEYAGE AAPAATTVVS PEELADEFSK 190 200 210 220 230 240 KKKNKKQAKQ AAVAENAGED EASDDEEGGS TVKSAAQKKK EKKERQKREA ALAKQKAATE 250 260 270 280 290 300 PKPKPVEKPA PEPEPVATEE VQPAAEEEEE KSSKNKKKGK KDKKAEPEEE KKDAKKKGMS 310 320 330 340 350 360 ASMVAAMQEQ LRKRKEEEER LEREEAERIR LEDEREEARL EAVRLEAERK EKKKQREAER 370 380 390 400 410 420 KARLKAEGKL LTKKQKEDRA RAQALLESLK AQGLEIPDPN DKRPTRPGTR IRPNKKKGPK 430 440 450 460 470 480 EEAAEEEAKA AEAEAQSAAA AAAAAAAEKA EEERVKESWD ATDSEAEPEP EEETSQATNN 490 500 510 520 530 540 GKTEAAEEEN EDTDDDEDDD DDEDDSDDSD GDSDDSREVS VLANDPESRR LRAEARILKR 550 560 570 580 590 600 QAEAEKKRST DELRAGVVCV LGHVDTGKTK ILDKLRRTHV QDSEAGGITQ QIGATNVPIE 610 620 630 640 650 660 AIKEQTKYVK AAAGFEHRLP GLLIIDTPGH ESFSNLRNRG SSLCDIAILV VDIMHGLEPQ 670 680 690 700 710 720 TIESIQLLKK KKCPFIVALN KIDRLYDWKQ LARRDVRDVL KEQQSNTQLE FQQRTKDVIL 730 740 750 760 770 780 QFAEQGLNAA LFYENTDPKT YISLVPTSAI SGEGMGNLLF MIADFCQNML AKRLMYSEEL 790 800 810 820 830 840 QATVLEVKAL PGLGTTIDAI LINGKLREGQ TMVVAGTDGP IVTQIRSLLM PQPMKELRVK 850 860 870 880 890 900 NAYVEYKEVK AAQGVKIAAK DLEKAIAGIN LLIAHKPDEV EICTEEVARE LKSALSHIKL 910 920 930 940 950 960 AQTGVHVQAS TLGSLEALLE FLRTSKIPYS AIRIGPVVKR DVMKASTMLE HEAQYATILA 970 980 990 1000 1010 1020 FDVKIEREAQ EMADSLGVKI FQADIIYHLF DKFTAYREEL KQKKREEFRS VAVFPCKLRI 1030 1040 1050 1060 1070 1080 LPQFVFNSRD PIVMGVMVEN GIVKVGTPIC VPSKEFVDIG IVTSIESNHK QIEFARKGQE 1090 1100 1110 1120 1130 1140 ICVKIDPIPG ESPKMFGRHF EADDMLISKI SRQSIDACKD YFRDDLIKAD WALMVELKKL FEIL

References

[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014296 Genomic DNA. Translation: AAF47774.2.
RefSeq	NP_651974.1.
UniGene	Dm.3325
3D structure databases
HSSP	HSSP built from PDB template 1G7S based on UniProtKB O26359.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VZP5. 2 interactions.
Genome annotation databases
Ensembl	FBgn0026259. Drosophila melanogaster. [Contig view]
GeneID	44261.
KEGG	dme:Dmel_CG10840.
NMPDR	fig|7227.3.peg.7954.
Organism-specific databases
FlyBase	FBgn0026259. eIF5B.
Phylogenomic databases
OMA	Q9VZP5. KIAANDL.
Gene expression databases
ArrayExpress	Q9VZP5.
Family and domain databases
InterPro	IPR015760. aIF-2. IPR000795. ProtSyn_GTP_bd. IPR005225. Small_GTP_bd. IPR004161. Transl_elong_EFTu/EF1A_2. [Graphical view]
PANTHER	PTHR23115:SF41. aIF-2. 1 hit.
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
TIGRFAMs	TIGR00231. small_GTP. 1 hit.
ProtoNet	Search...
Other Resources
NextBio	837060.

Entry information

Entry name

Q9VZP5_DROME

Accession

Primary (citable) accession number: Q9VZP5

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 72 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)