##gff-version 3
Q9VZI2	UniProtKB	Chain	1	1073	.	.	.	ID=PRO_0000449972;Note=Activated Cdc42 kinase Ack	
Q9VZI2	UniProtKB	Domain	123	383	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9VZI2	UniProtKB	Domain	386	446	.	.	.	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192	
Q9VZI2	UniProtKB	Domain	1029	1072	.	.	.	Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212	
Q9VZI2	UniProtKB	Region	88	110	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VZI2	UniProtKB	Region	484	506	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VZI2	UniProtKB	Region	803	834	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VZI2	UniProtKB	Region	862	882	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VZI2	UniProtKB	Compositional bias	92	110	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VZI2	UniProtKB	Compositional bias	805	834	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VZI2	UniProtKB	Active site	250	250	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9VZI2	UniProtKB	Binding site	129	137	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9VZI2	UniProtKB	Binding site	156	156	.	.	.	Ontology_term=ECO:0000255,ECO:0000269;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000269|PubMed:27462444;Dbxref=PMID:27462444	
Q9VZI2	UniProtKB	Mutagenesis	156	156	.	.	.	Note=Loss of enzyme activity. Increase in apoptotic cells in the eye and wing. Increase in bristle number in the interommatidial lattice and decrease in pigment cell number. Disrupts vesicular localization of dock in spermatocytes. Fails to rescue the nurse cell plasma membrane defects and male sterility observed in null mutants. Fails to rescue the small eye phenotype induced by hid but able to rescue the small eye phenotype induced by rpr. K->A;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11773052,ECO:0000269|PubMed:22615583,ECO:0000269|PubMed:23562806,ECO:0000269|PubMed:25223282;Dbxref=PMID:11773052,PMID:22615583,PMID:23562806,PMID:25223282	
Q9VZI2	UniProtKB	Mutagenesis	156	156	.	.	.	Note=Loss of enzyme activity. Many embryos die before hatching. Fails to promote yki-dependent tissue growth in the eye and wing. Overexpression in wing imaginal disks frequently results in wings with blisters and ectopic veins. Eyes are disorganized and ommatidia are almost completely absent%2C eye bristles are not present in posterior two-thirds of the eye and bristle clusters occur at the anterior end. Increased Egfr endocytosis in embryos. No effect on Dpp expression in the leading edge cells. K->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11997505,ECO:0000269|PubMed:23579691,ECO:0000269|PubMed:27462444;Dbxref=PMID:11997505,PMID:23579691,PMID:27462444	
Q9VZI2	UniProtKB	Mutagenesis	549	551	.	.	.	Note=Able to rescue male sterility. LID->AAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23562806;Dbxref=PMID:23562806