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Q9VZ64

- 6PGL_DROME

UniProt

Q9VZ64 - 6PGL_DROME

Protein

Probable 6-phosphogluconolactonase

Gene

CG17333

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.By similarity

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.By similarity

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    ReactomeiREACT_210042. Pentose phosphate pathway (hexose monophosphate shunt).
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable 6-phosphogluconolactonase (EC:3.1.1.31)
    Short name:
    6PGL
    Gene namesi
    ORF Names:CG17333
    OrganismiDrosophila melanogaster (Fruit fly)
    Taxonomic identifieri7227 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000803: Chromosome X

    Organism-specific databases

    FlyBaseiFBgn0030239. CG17333.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 243243Probable 6-phosphogluconolactonasePRO_0000090081Add
    BLAST

    Proteomic databases

    PaxDbiQ9VZ64.
    PRIDEiQ9VZ64.

    Expressioni

    Gene expression databases

    BgeeiQ9VZ64.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9VZ64.
    SMRiQ9VZ64. Positions 9-239.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0363.
    GeneTreeiENSGT00550000075110.
    InParanoidiQ9VZ64.
    KOiK01057.
    OMAiERVCAWE.
    OrthoDBiEOG7RZ5QV.
    PhylomeDBiQ9VZ64.

    Family and domain databases

    InterProiIPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view]
    PfamiPF01182. Glucosamine_iso. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01198. pgl. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9VZ64-1 [UniParc]FASTAAdd to Basket

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    MSEKKGALKV IPSASEEQLV QALGDLLQRC SQEALAKHDK FSVGLSGGSL    50
    VQLLTKALKS CNLKTAKWVF FFCDERYVRL DDSDSTYGAY RAEWLTQLPC 100
    IQESQFVRAD TSQPLDACAA DYEAKVKSQV DRFDLLLLGM GPDGHTCSLF 150
    PEQPATLQET KRLVIPIRNS PKPPPERITF TLPLINKARN VAFVVTGAAK 200
    ASVVKSVFVD LDKKFPAAWV NPTKGQLTLI VDAGAGKEIE TLK 243
    Length:243
    Mass (Da):26,672
    Last modified:May 1, 2000 - v1
    Checksum:i0E23EFDCF5FE042E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014298 Genomic DNA. Translation: AAF47963.1.
    BT012304 mRNA. Translation: AAS77429.1.
    RefSeqiNP_572656.1. NM_132428.3.
    UniGeneiDm.23623.

    Genome annotation databases

    EnsemblMetazoaiFBtr0073379; FBpp0073235; FBgn0030239.
    GeneIDi32013.
    KEGGidme:Dmel_CG17333.
    UCSCiCG17333-RA. d. melanogaster.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014298 Genomic DNA. Translation: AAF47963.1 .
    BT012304 mRNA. Translation: AAS77429.1 .
    RefSeqi NP_572656.1. NM_132428.3.
    UniGenei Dm.23623.

    3D structure databases

    ProteinModelPortali Q9VZ64.
    SMRi Q9VZ64. Positions 9-239.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q9VZ64.
    PRIDEi Q9VZ64.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0073379 ; FBpp0073235 ; FBgn0030239 .
    GeneIDi 32013.
    KEGGi dme:Dmel_CG17333.
    UCSCi CG17333-RA. d. melanogaster.

    Organism-specific databases

    FlyBasei FBgn0030239. CG17333.

    Phylogenomic databases

    eggNOGi COG0363.
    GeneTreei ENSGT00550000075110.
    InParanoidi Q9VZ64.
    KOi K01057.
    OMAi ERVCAWE.
    OrthoDBi EOG7RZ5QV.
    PhylomeDBi Q9VZ64.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    Reactomei REACT_210042. Pentose phosphate pathway (hexose monophosphate shunt).

    Miscellaneous databases

    GenomeRNAii 32013.
    NextBioi 776368.
    PROi Q9VZ64.

    Gene expression databases

    Bgeei Q9VZ64.

    Family and domain databases

    InterProi IPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view ]
    Pfami PF01182. Glucosamine_iso. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01198. pgl. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Drosophila melanogaster."
      Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
      , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
      Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Berkeley.
    2. Cited for: GENOME REANNOTATION.
      Strain: Berkeley.
    3. Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A., Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.
      Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Berkeley.
      Tissue: Larva and Pupae.

    Entry informationi

    Entry namei6PGL_DROME
    AccessioniPrimary (citable) accession number: Q9VZ64
    Secondary accession number(s): Q53XD9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 19, 2003
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3