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Protein
Submitted name:

Uncharacterized protein

Gene

CG43155

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiR-DME-1299344. TWIK-related spinal cord K+ channel (TRESK).

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:CG43155Imported, Dmel_CG43155Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0262685. CG43155.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei66 – 86HelicalSequence analysisAdd BLAST21
Transmembranei160 – 178HelicalSequence analysisAdd BLAST19
Transmembranei190 – 208HelicalSequence analysisAdd BLAST19
Transmembranei239 – 262HelicalSequence analysisAdd BLAST24
Transmembranei269 – 289HelicalSequence analysisAdd BLAST21
Transmembranei295 – 317HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9VYY5.
PRIDEiQ9VYY5.

Expressioni

Gene expression databases

GenevisibleiQ9VYY5. DM.

Interactioni

Protein-protein interaction databases

IntActiQ9VYY5. 1 interactor.
STRINGi7227.FBpp0294058.

Structurei

3D structure databases

ProteinModelPortaliQ9VYY5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 214Ion_trans_2InterPro annotationAdd BLAST60
Domaini249 – 319Ion_trans_2InterPro annotationAdd BLAST71

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00700000104522.
InParanoidiQ9VYY5.
KOiK05323.
OMAiKWNSKKN.
OrthoDBiEOG091G0U1I.
PhylomeDBiQ9VYY5.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

Q9VYY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPMKKVTVKE YDSQDEASTE LLEKLKHLDR RVDAAEGGGL AKGTAGGRRS
60 70 80 90 100
TACWQSMKWK SALNHIGLLV SLSIYCGVGG LIFRHLERPA EVERLSHLKD
110 120 130 140 150
IVKTHRERFL HTILNNTEVH NLDELLSFEL AKYEAAVQQA AEGGLLIVAD
160 170 180 190 200
KDFPEPYERW SILQAVFFSS TVLTTIGYGN IVPVTTGGRV FCICFALIGI
210 220 230 240 250
PFTLTVIADW GRLFATAVSV FGKHMPTKPK FTNFIGKTWF YAILAVGFLG
260 270 280 290 300
VYLAAGAGLL LLWEDDWTFF DGFYFCFITM TTIGFGDLVP KKPNYMLLCT
310 320 330 340 350
LYILIGLALT STIIELVRRQ YATSWAKLQE LSGPMAETLR RLGETAGTGL
360 370 380 390 400
DYTALQKVLT VSMPKWNSKK NEHSPDIAAL EAITNAILKE VKEAQNNKPK
410
VLQIVIYESS V
Length:411
Mass (Da):45,728
Last modified:June 26, 2013 - v2
Checksum:i5C81E1767EA7EB74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48048.2.
RefSeqiNP_572720.2. NM_132492.3.

Genome annotation databases

EnsemblMetazoaiFBtr0305607; FBpp0294058; FBgn0262685.
GeneIDi32092.
KEGGidme:Dmel_CG43155.
UCSCiCG1756-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48048.2.
RefSeqiNP_572720.2. NM_132492.3.

3D structure databases

ProteinModelPortaliQ9VYY5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9VYY5. 1 interactor.
STRINGi7227.FBpp0294058.

Proteomic databases

PaxDbiQ9VYY5.
PRIDEiQ9VYY5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0305607; FBpp0294058; FBgn0262685.
GeneIDi32092.
KEGGidme:Dmel_CG43155.
UCSCiCG1756-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0262685. CG43155.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00700000104522.
InParanoidiQ9VYY5.
KOiK05323.
OMAiKWNSKKN.
OrthoDBiEOG091G0U1I.
PhylomeDBiQ9VYY5.

Enzyme and pathway databases

ReactomeiR-DME-1299344. TWIK-related spinal cord K+ channel (TRESK).

Miscellaneous databases

GenomeRNAii32092.

Gene expression databases

GenevisibleiQ9VYY5. DM.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VYY5_DROME
AccessioniPrimary (citable) accession number: Q9VYY5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: June 26, 2013
Last modified: October 5, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.