Q9VYT4 (Q9VYT4_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP7 EMBL AAF48104.3
EC=3.6.3.4 EMBL AAF48104.3

Gene names

Name:	ATP7 FlyBase FBgn0030343
ORF Names:	Dmel_CG1886 EMBL AAF48104.3

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1254 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS023306
Ligand	ATP-binding RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653 EMBL AAF48104.3
PTM	Phosphoprotein RuleBase RU000653
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro adult chitin-containing cuticle pigmentation Inferred from mutant phenotype. Source: FlyBase cellular copper ion homeostasis Inferred from mutant phenotype. Source: FlyBase larval development Inferred from mutant phenotype. Source: FlyBase
Cellular component	cytoplasm Inferred from direct assay. Source: FlyBase integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW copper ion binding Inferred from electronic annotation. Source: InterPro copper-exporting ATPase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9VYT4 [UniParc]. Last modified March 3, 2009. Version 3. Checksum: 15EC83DDA66EA403	FASTA	1,254	136,082
	10 20 30 40 50 60 MPSDERVEAT MSTVRLPIVG MTCQSCVRNI TEHIGQKSGI LGVRVILEEN AGYFDYDPRQ 70 80 90 100 110 120 TDPARIASDI DDMGFECSYP GDAADPPETP ASAWTNIRVV GMTCQSCVRN IEGNIGTKPG 130 140 150 160 170 180 IHSIEVQLAA KNARVQYDPA QYDPAQIAEL IDDMGFEASV QEPRSPSQSP SPAPASSPKK 190 200 210 220 230 240 RATPTPPPPS YAQNGSAVAI PVEQELLTKC FLHIRGMTCA SCVAAIEKHC KKIYGLDSIL 250 260 270 280 290 300 VALLAAKAEV KFNANVVTAE NIAKSITELG FPTELIDEPD NGEAEVELEI MGMTCASCVN 310 320 330 340 350 360 KIESHVLKIR GVTTASVTLL TKRGKFRYIT EETGPRSICE AIEALGFEAK LMTGRDKMAH 370 380 390 400 410 420 NYLEHKEEIR KWRNAFLVSL IFGGPCMVAM IYFMLEMSDK GHANMCCLVP GLSMENLVMF 430 440 450 460 470 480 LLSTPVQFFG GFHFYVQSYR AIKHGTTNMD VLISMVTTIS YVYSVAVVIA AVLLEQNSSP 490 500 510 520 530 540 LTFFDTPPML LIFISLGRWL EHIAKGKTSE ALSKLLSLKA ADALLVEISP DFDIISEKVI 550 560 570 580 590 600 SVDYVQRGDI LKVIPGAKVP VDGKVLYGHS SCDESLITGE SMPVAKRKGS VVIGGSINQN 610 620 630 640 650 660 GVLLVEATHT GENTTLAQIV RLVEEAQTSK APIQQLADRI AGYFVPFVVV VSSITLIAWI 670 680 690 700 710 720 IIGFSNPNLV PVAMEHKMHM DQNTIIVSYA FKCALSVLAI ACPCALGLAT PTAVMVATGT 730 740 750 760 770 780 GAINGVLVKG ATALENAHKV KTVVFDKTGT ITHGTPMTSK VTLFVTAQVC SLARALTIVG 790 800 810 820 830 840 AAEQNSEHPI ASAIVHFAKD MLNVGATPQA GSFGKSSHFQ AVPGCGIRVT VSNYEQTLRQ 850 860 870 880 890 900 ACNADRIINY ENLHRTHPQG SVPVDNGASI EHLLPQRSVR KSMELNNQQL LSDLVLEPEE 910 920 930 940 950 960 ELLTDQKIID SPEILVLIGN REWMERNAIE VPLEISDCMT HEERKGHTAV LCALNGQLVC 970 980 990 1000 1010 1020 MFAVSDMVKP EAHLAVYTLK RMGIDVVLLT GDNKNTAASI AREVGIRTVY AEVLPSHKVA 1030 1040 1050 1060 1070 1080 KIQRIQANGI RVAMVGDGVN DSPALAQADV GITIAAGTDV AAEASDIVLM RNDLLDVVAC 1090 1100 1110 1120 1130 1140 LDLSRCTVRR IRYNFFFASM YNLLGIPLAS GLFAPYGFTL LPWMASVAMA ASSVSVVCSS 1150 1160 1170 1180 1190 1200 LLLKMYRKPT AKTLRTAEYE AQLAAERASG SEDELDKLSL HRGLDDLPEK GRMPFKRSST 1210 1220 1230 1240 1250 SLISRIFMHD YGNITSPDAK YGEGLLDPEE QYDGRTKIVR SRFHANDSTE LQKL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014298 Genomic DNA. Translation: AAF48104.3.
RefSeq	NP_572756.3. NM_132528.2.
UniGene	Dm.18759.
3D structure databases
ProteinModelPortal	Q9VYT4.
SMR	Q9VYT4. Positions 13-1152.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-324878.
STRING	Q9VYT4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0273257; FBpp0271765; FBgn0030343.
GeneID	32142.
KEGG	dme:Dmel_CG1886.
UCSC	CG1886-RB. d. melanogaster.
Organism-specific databases
CTD	32142.
FlyBase	FBgn0030343. ATP7.
Phylogenomic databases
eggNOG	inNOG07805.
GeneTree	EMGT00050000001937.
InParanoid	Q9VYT4.
OrthoDB	EOG4C8677.
PhylomeDB	Q9VYT4.
Gene expression databases
ArrayExpress	Q9VYT4.
Bgee	Q9VYT4.
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR006403. ATPase_P-typ_cat/Cu-transptr. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR006416. ATPase_P-typ_heavy-metal. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. IPR017969. Heavy-metal-associated_CS. IPR006121. HeavyMe-assoc_HMA. IPR006122. HMA_Cu_ion-bd. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 1 hit. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 2 hits. G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
KO	K01533.
Pfam	PF00122. E1-E2_ATPase. 1 hit. PF00403. HMA. 4 hits. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00942. CUATPASEI.
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit. SSF55008. HeavyMe_transpt. 4 hits.
TIGRFAMs	TIGR01525. ATPase-IB_hvy. 1 hit. TIGR01494. ATPase_P-type. 1 hit. TIGR00003. TIGR00003. 3 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. PS01047. HMA_1. 3 hits. PS50846. HMA_2. 4 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	777072.

Entry information

Entry name

Q9VYT4_DROME

Accession

Primary (citable) accession number: Q9VYT4

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 105 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)