Unreviewed, UniProtKB/TrEMBL Q9VYT3 (Q9VYT3_DROME)

Names and origin

Protein names

Submitted name:
    CG2025 EMBL AAF48105.2
    EC=3.4.24.61

Gene names

ORF Names:

CG2025 FlyBase FBgn0030344, Dmel_CG2025 EMBL AAF48105.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1147 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the peptidase M16 family. RuleBase RU004447V0

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
Arpc3B	Q9VX82	1	EBI-138113,EBI-177874

Sequences

	Sequence		Length	Mass (Da)
	Q9VYT3-1 [UniParc]. Last modified October 1, 2002. Version 2. Checksum: 2308A76321C84E5D	FASTA	1,147	132,763
	10 20 30 40 50 60 MLWQRYSAHL FRRFEFHVRT KRRSPITQLA GVRAITYSSL CKMTDQVKYL DIPDKSETDK 70 80 90 100 110 120 KLYKTLLLGN GLHALIVSDP SPMPHDGFTT SESSSSKSTV STSSSIISRS ESTSSTSTDS 130 140 150 160 170 180 ESSEESSSEE GDEKLAACAL LIDYGSFAEP TKYQGLAHFL EHMIFMGSEK YPKENIFDAH 190 200 210 220 230 240 IKKCGGFANA NTDCEDTLFY FEVAEKHLDS SLDYFTALMK APLMKQEAMQ RERSAVDSEF 250 260 270 280 290 300 QQILQDDETR RDQLLASLAT KGFPHGTFAW GNMKSLKENV DDAELHKILH EIRKEHYGAN 310 320 330 340 350 360 RMYVCLQARL PIDELESLVV RHFSGIPHNE VKAPDLSSFN YKDAFKAEFH EQVFFVKPVE 370 380 390 400 410 420 NETKLELTWV LPNVRQYYRS KPDQFLSYLL GYEGRGSLCA YLRRRLWALQ LIAGIDENGF 430 440 450 460 470 480 DMNSMYSLFN ICIYLTDEGF KNLDEVLAAT FAYVKLFANC GSMKDVYEEQ QRNEETGFRF 490 500 510 520 530 540 HAQRPAFDNV QELVLNLKYF PPKDILTGKE LYYEYNEEHL KELISHLNEM KFNLMVTSRR 550 560 570 580 590 600 KYDDISAYDK TEEWFGTEYA TIPMPEKWRK LWEDSVPLPE LFLPESNKYV TDDFTLHWHS 610 620 630 640 650 660 MGRPEVPDSP KLLIKTDTCE LWFRQDDKFD LPEAHMAFYF ISPMQRQNAK NDAMCSLYEE 670 680 690 700 710 720 MVRFHVCEEL YPAISAGLSY SLSTIEKGLL LKVCGYNEKL HLIVEAIAEG MLNVAETLDE 730 740 750 760 770 780 NMLSAFVKNQ RKAFFNALIK PKALNRDIRL CVLERIRWLM INKYKCLSSV ILEDMREFAH 790 800 810 820 830 840 QFPKELYIQS LIQGNYTEES AHNVMNSLLS RLNCKQIRER GRFLEDITVK LPVGTSIIRC 850 860 870 880 890 900 HALNVQDTNT VITNFYQIGP NTVRVESILD LLMMFVDEPL FDQLRTKEQL GYHVGATVRL 910 920 930 940 950 960 NYGIAGYSIM VNSQETKTTA DYVEGRIEVF RAKMLQILRH LPQDEYEHTR DSLIKLKLVA 970 980 990 1000 1010 1020 DLALSTEMSR NWDEIINESY LFDRRRRQIE VLRTLQKDEI INFVISIDGD NMRKLSVQVI 1030 1040 1050 1060 1070 1080 GHRPAGMPEP LCGEDTAKCA SKSDDESESE NDDDDDEDEE EEESSEEEEE EEKEKEGLKG 1090 1100 1110 1120 1130 1140 EDEDDLFYSL ENKLNIVFLP AKFNNAFIIT DIEKFKDDQY VYPQQKTQPK EEDELISAHI ADAIRQV

References

[1]

"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

[2]

"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014298 Genomic DNA. Translation: AAF48105.2.
RefSeq	NP_572757.2.
UniGene	Dm.1603
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9VYT3. 1 interaction.
Genome annotation databases
Ensembl	FBgn0030344. Drosophila melanogaster. [Contig view]
GeneID	32143.
KEGG	dme:Dmel_CG2025.
NMPDR	fig|7227.3.peg.17508.
Organism-specific databases
FlyBase	FBgn0030344. CG2025.
Phylogenomic databases
OMA	Q9VYT3. FANANTD.
Gene expression databases
ArrayExpress	Q9VYT3.
Family and domain databases
InterPro	IPR011237. Pept_M16_core. IPR011765. Pept_M16_N. IPR001431. Pept_M16_Zn_BS. IPR007863. Peptidase_M16_C. [Graphical view]
Gene3D	G3DSA:3.30.830.10. Pept_M16_core. 1 hit.
Pfam	PF00675. Peptidase_M16. 1 hit. PF05193. Peptidase_M16_C. 2 hits. [Graphical view]
PROSITE	PS00143. INSULINASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	777077.

Entry information

Entry name

Q9VYT3_DROME

Accession

Primary (citable) accession number: Q9VYT3

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)