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Q9VYF3

- Q9VYF3_DROME

UniProt

Q9VYF3 - Q9VYF3_DROME

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Protein
Submitted name: FI19806p1
Gene
HDAC4, HDAC4-RD, CG1770, Dmel_CG1770
Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. histone deacetylase activity Source: FlyBase
Complete GO annotation...

GO - Biological processi

  1. histone deacetylation Source: GOC
  2. regulation of transcription, DNA-templated Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotationsImported

Names & Taxonomyi

Protein namesi
Submitted name:
FI19806p1Imported
Submitted name:
HDAC4, isoform DImported (EC:3.5.1.-Imported)
Gene namesi
Name:HDAC4Imported
Synonyms:HDAC4-RDImported
ORF Names:CG1770Imported, Dmel_CG1770Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome X

Organism-specific databases

FlyBaseiFBgn0041210. HDAC4.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: FlyBase
  2. histone deacetylase complex Source: InterPro
  3. nucleus Source: FlyBase
Complete GO annotation...

Interactioni

Protein-protein interaction databases

MINTiMINT-1579842.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000062809.
InParanoidiQ9VYF3.
KOiK11406.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017320. Histone_deAcase_II_euk.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037911. HDAC_II_euk. 1 hit.
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Complete.

Q9VYF3-1 [UniParc]FASTAAdd to Basket

« Hide

MSSPDDRIPI HDLPSEAGSD ERLLHITPAT LTLDFKPHPA VDIDQQIMEL     50
KKSQELQKQR LINSFQEQSK QMELEHKLQL EHKYQFAVNS HGAFQELRNE 100
SMVTAAAAAV AQEQHRQQLH QQQQQHQQQQ QQQQHQQQQQ QQQARGRDGM 150
KLKQNCSANA SPEVKQILNC FILSRKSQAA ASNGTTTTSP YRNRGVVKSS 200
SGESLPAGTV TSAHPYKIPQ PPPSLLKYES DFPLRKTASE PNLLKIRLKQ 250
SVIERKARIG GPAGARRHER LLQAAQRRQQ KNSVLTNCNS TPDSGPNSPP 300
SAAALAVGVV GSRGSPTSAP IQEENEEGSQ YQPGQRSSIN DLPLFSSPSL 350
PNISLGRPHL PNSAQAHAQV NAQVAAQAQA QAQAQAQAHA MFAALAAAQG 400
GCGQPGYYNP LGMAFVGRQP APLAMIPATG IAPQQPSPVV RSASATSTSS 450
SQASLVGDVA PPQAHAASTI LPSSSSYMQQ LGSVAGSGVN LHAAAVAAAA 500
AAAAAAGSLP PTNSHGHGHG SHAHPHPHAH GHGHGHGHGI YAGHQHNVPI 550
TDAQVAQVHL HKQGHRPLGR TQSAPLPLGH PMLTGAVQLN VVQTHYENSE 600
AERQAYEHQV VNQKVRQTVL TRSGAAAAAA AAAGVSVVRE AQLKEEDDDS 650
AAEVMDLTDK KKPPKTVLTS TIATSTSQNL PEALAAAAAA AAYRAPHNAS 700
SNSASATKSG IKLRDQEYLQ QQREQLLLLQ QEEELAKSLM RPLSRTLSSP 750
LVPLGPHGLS QIPDTGQQPA PIATSSSADH IPPVNLSLPH RQHRQLMSTL 800
YASQLRNHQP SASGSPPHKV TTGLAYDPLM LKHSCICGDN AQHPEHSGRL 850
QSVWARLNET DLVKRCDRLR ARKATQEELQ TVHTEAHAML FGSNQCQLSR 900
PKLENTLSAS FVRLSCGGLG VDLDTTWNEH HTATAARMAA GCVIDLALKT 950
AKGDLRNGFA VVRPPGHHAE ANLAMGFCFF NSIAIAAKLL RQRMPEVRRI 1000
LIVDWDVHHG NGTQQAFYQS PDILYLSIHR HDDGNFFPGT GGPTECGSGA 1050
GLGFNVNISW SGALNPPLGD AEYIAAFRTV VMPIARSFNP DIVLVSSGFD 1100
AATGHPAPLG GYHVSPACFG FMTRELLQLA NGKVVLALEG GYDLAAICDS 1150
AQECVRALLG DPAAPIAKAE LERPPCQNAI NTLQKTIAIQ QTHWPCVRML 1200
EHTVGLSALE TLKVEHDESE TINAMAGLSM QSMHRTLSRD DSEEPMDQDE 1250
TK 1252
Length:1,252
Mass (Da):134,162
Last modified:November 30, 2010 - v3
Checksum:iC6FE30273DDC1EC5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014298 Genomic DNA. Translation: AAF48245.3.
BT133402 mRNA. Translation: AFH55501.1.
RefSeqiNP_572868.3. NM_132640.5.
UniGeneiDm.6484.

Genome annotation databases

EnsemblMetazoaiFBtr0301298; FBpp0290513; FBgn0041210.
GeneIDi32278.
KEGGidme:Dmel_CG1770.
UCSCiCG1770-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014298 Genomic DNA. Translation: AAF48245.3 .
BT133402 mRNA. Translation: AFH55501.1 .
RefSeqi NP_572868.3. NM_132640.5.
UniGenei Dm.6484.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

MINTi MINT-1579842.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0301298 ; FBpp0290513 ; FBgn0041210 .
GeneIDi 32278.
KEGGi dme:Dmel_CG1770.
UCSCi CG1770-RA. d. melanogaster.

Organism-specific databases

CTDi 9759.
FlyBasei FBgn0041210. HDAC4.

Phylogenomic databases

GeneTreei ENSGT00530000062809.
InParanoidi Q9VYF3.
KOi K11406.

Miscellaneous databases

GenomeRNAii 32278.
NextBioi 777716.

Family and domain databases

Gene3Di 3.40.800.20. 1 hit.
InterProi IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017320. Histone_deAcase_II_euk.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 1 hit.
[Graphical view ]
PIRSFi PIRSF037911. HDAC_II_euk. 1 hit.
PRINTSi PR01270. HDASUPER.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  3. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  6. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  7. "Drosophila melanogaster release 4 sequence."
    Berkeley Drosophila Genome Project
    Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  8. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  9. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  11. Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.
    Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  12. FlyBase
    Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9VYF3_DROME
AccessioniPrimary (citable) accession number: Q9VYF3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: November 30, 2010
Last modified: June 11, 2014
This is version 108 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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