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Unreviewed, UniProtKB/TrEMBL Q9VYA6 (Q9VYA6_DROME)

Last modified June 16, 2009. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    NFAT, isoform A EMBL AAF48297.1
Gene names
Name: NFAT EMBL AAF48297.1
ORF Names: Dmel_CG11172 EMBL AAF48297.1
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

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Protein attributes

Sequence length1419 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Sequence similarities

Contains 1 RHD (Rel-like) domain. RuleBase RU003997V0

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Ontologies

Keywords
   Cellular componentNucleus RuleBase RU003998V0
Gene Ontology (GO)
   Biological processregulation of transcription, DNA-dependent

Inferred from electronic annotation. Source: InterPro

   Cellular componentnucleus

Inferred from electronic annotation. Source: InterPro

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

Q9VDD01EBI-103041,EBI-162785

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Sequences

Sequence LengthMass (Da)Tools
Q9VYA6-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 8B3F19072DC02E11

FASTA1,419150,676
        10         20         30         40         50         60 
MLLKFTKTSG AGPSAVPLLT TAPATVTSSA SMQATTTSYA ARGTGMRMTM STNSTMSARI 

        70         80         90        100        110        120 
HRKGFRIPSK RQPGKGLPGK LHTITRTGPG KMVPGKRIPQ RPHPPPCDNS NDSGLGFDQH 

       130        140        150        160        170        180 
TELRSSAGAG GVTDPAANGG SGSNSGQRSS LLVNSALTNT VAAAAAAAAA AVASNTLQQH 

       190        200        210        220        230        240 
QQHHQQQQQQ QQQQQQQQQQ QQQQQQQQQH SPQQHLIRAI PVSRSRNNTK VMAHCLEDLD 

       250        260        270        280        290        300 
LISASSEDSS TIATPAGLDE DTGFVNDTKT TTTGGNSSSD PFGGVFQATE AAVAAAVNAF 

       310        320        330        340        350        360 
NLQQQQHSVQ QQQHQLFQYN GLLLQPQQQL QQQQSHHQQQ QQQQQHHRHG KHIKRKKLEC 

       370        380        390        400        410        420 
NQVELDNDDA CSEDEFIRKI ASSVTMSPTL EATPSPPPIV ASVAPATTIV SLLPLISSGN 

       430        440        450        460        470        480 
SNNNNNNNNI ETKFISARNV TRVANKRQPT TPLNSVASSN DGQVQLEILS QPEQQHRARY 

       490        500        510        520        530        540 
QTEGSRGAVK DRSGNGFPIV RLTGYDKVAV LQVFIGTDIG RVAPHMFYQA CKVAGKNSTQ 

       550        560        570        580        590        600 
CNEKKVDGTM VIEIDFKPET DMTITCDCVG ILKERNVDVE HRFPEHLAQK NKKKSTRCRM 

       610        620        630        640        650        660 
VFRTQLTRDD GTTETLQVCS NPIICTQPPG VPEICKKSLN SCPVDGGLEL FIIGKNFLKD 

       670        680        690        700        710        720 
THVVFQETYD SVNGDDPATE IAVRQQLIGG TAALWEQSVL PDKEYLHQTH LICTVPPYLH 

       730        740        750        760        770        780 
QNILKPVQVQ VSIVSSGKKS EPHTFTYTAK GQYTTLAAAS TLSNTIHAQD VSGFMDTTSA 

       790        800        810        820        830        840 
SNASGSSGWS AAGGSGNNTS TGDNVEAKHE IDSGMMPPPI TTQIPMGVRR SSLPSVTPMI 

       850        860        870        880        890        900 
TDQQLVHLNA VAASAEALKT ELDDSNSHSP LTGESTPDSP NAALQYHRFA RKPSLDTIMY 

       910        920        930        940        950        960 
DQSNSLPGFP TVVAPATAAA VAAAVDIDPT AVAVAVELAV KNEIVKHVVQ QHQQMQEQMH 

       970        980        990       1000       1010       1020 
EQQQQQQQQQ QQQQQQQQQQ PQQQQQQQVH KFIDELTKST SVVSSNGTTE PALFTTSAVI 

      1030       1040       1050       1060       1070       1080 
DHALTDILQA KVGIAPPNVV LERSLSLSST NSSSSMSGSE SSPNSSPLTQ DIILNSEPAA 

      1090       1100       1110       1120       1130       1140 
ALAGAAALGG PAPVDVTGGL STDIIMNPAV SPSTILCSAN GAATAVVPNI LAPHQVTMAN 

      1150       1160       1170       1180       1190       1200 
SILNDIAMQP EPTQQDAAVA ALALSNIMMS PPTAASGVGV GDTLPPTPAT MQPEVAATAT 

      1210       1220       1230       1240       1250       1260 
STAVSNMIIK AAADFITTQE QEQHHYHHHG RIHSHSPQAA VGVSGNPAET ASDPLVDLLL 

      1270       1280       1290       1300       1310       1320 
NHSNTPETAA AAAAAVAVEA ANFQSMNHSH HSHHGHHGHS HGHGHSRVTG HVSGHVTSHH 

      1330       1340       1350       1360       1370       1380 
RGHHLPVVPP TPQESLIVAL ASENALQKSV ATAAVTTNGA VMTQQASAPN TAGSILPAAV 

      1390       1400       1410 
GAVAAAAAVA VQPPIPQELT TMSDQDLISY INPSTFDQL

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References

[1]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.

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Cross-references

Sequence databases

AE014298 Genomic DNA. Translation: AAF48297.1.
RefSeqNP_511147.2.
UniGeneDm.2918

3D structure databases

HSSPHSSP built from PDB template 1IMH based on UniProtKB O94916.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9VYA6. 2 interactions.

Proteomic databases

PRIDEQ9VYA6.

Genome annotation databases

EnsemblFBgn0030505. Drosophila melanogaster. [Contig view]
GeneID32321.
NMPDRfig|7227.3.peg.17728.

Organism-specific databases

FlyBaseFBgn0030505. NFAT.

Phylogenomic databases

HOGENOMQ9VYA6.
OMAQ9VYA6. MSARIHR.

Gene expression databases

ArrayExpressQ9VYA6.

Family and domain databases

InterProIPR013783. Ig-like_fold.
IPR002909. IPT_TIG_rcpt.
IPR008366. NFAT.
IPR011539. RHD.
[Graphical view]
Gene3DG3DSA:2.60.40.10. Ig-like_fold. 1 hit.
G3DSA:2.60.40.340. RHD. 1 hit.
PANTHERPTHR12533. NFAT. 1 hit.
PfamPF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view]
SMARTSM00429. IPT. 1 hit.
[Graphical view]
PROSITEPS50254. REL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio777928.

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Entry information

Entry nameQ9VYA6_DROME
AccessionPrimary (citable) accession number: Q9VYA6
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: June 16, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequences · References · Cross-references · Entry information