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Protein
Submitted name:

LD24737p

Gene

l(1)G0007

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent RNA helicase activity Source: FlyBase
  • RNA binding Source: GO_Central

GO - Biological processi

  • inter-male aggressive behavior Source: FlyBase
  • mRNA splicing, via spliceosome Source: FlyBase
  • regulation of alternative mRNA splicing, via spliceosome Source: FlyBase

Keywordsi

Molecular functionHydrolaseSAAS annotationImported
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DME-109688. Cleavage of Growing Transcript in the Termination Region.
R-DME-159236. Transport of Mature mRNA derived from an Intron-Containing Transcript.
R-DME-72163. mRNA Splicing - Major Pathway.
R-DME-72187. mRNA 3'-end processing.

Names & Taxonomyi

Protein namesi
Submitted name:
LD24737pImported
Submitted name:
Lethal (1) G0007, isoform AImported (EC:3.6.1.3Imported)
Gene namesi
Name:l(1)G0007Imported
Synonyms:CG1375Imported
ORF Names:CG32604Imported, Dmel_CG32604Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0026713. l(1)G0007.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • spliceosomal complex Source: FlyBase

Expressioni

Gene expression databases

BgeeiFBgn0026713.

Interactioni

Protein-protein interaction databases

IntActiQ9VY54. 4 interactors.
MINTiMINT-334469.
STRINGi7227.FBpp0073717.

Structurei

3D structure databases

SMRiQ9VY54.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini544 – 707Helicase ATP-bindingInterPro annotationAdd BLAST164
Domaini729 – 904Helicase C-terminalInterPro annotationAdd BLAST176

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1164 – 1202Sequence analysisAdd BLAST39

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0925. Eukaryota.
COG1643. LUCA.
GeneTreeiENSGT00880000137867.
KOiK12815.
OMAiPSRSTWE.
OrthoDBiEOG091G030Q.

Family and domain databases

InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9VY54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDDDESGVH RLEGTAGQET RGGLVIRKPK DAGAGGGGGF KVPQGSMLGL
60 70 80 90 100
DKLAAKRRAE KERSERLISF KDSEFDDTGG GSSTPQANAS GASSEFAFKK
110 120 130 140 150
PDTKSFEKLR GQLREHKDDT PSHTGGVSEK ARERLREHIQ RDRKRGPVSS
160 170 180 190 200
TAAEGRDRDR DWDRDRRRDR DRDRDRDRDR RQHRERERDR HRSWDRDRGR
210 220 230 240 250
DRDRDRSMSE RSVHTPREPG TPGGSSGGIS NSSWDDEDGE FGQRKSDWDM
260 270 280 290 300
PTPRRHGNKS GDWSVRSGGS RRNHGRQDDT VRPTPAHRYN QWAHGRKRSG
310 320 330 340 350
ATPWGEDPES LDLWEEEQRR LDREWYNIDE GYDDENNPFG GPNSEYFRKR
360 370 380 390 400
EEQLEQKRTK RISAQQRQNN RDNELWERNR MLTSGVVTLI SVNDDFDEEA
410 420 430 440 450
LERVHLLVHH IIPPFLDGRI VFTKQPEPVV PVKDPTSDMA LLARKGSALV
460 470 480 490 500
RNYREQKERR KAQKKHWELS GTKLGNIMGV QRPQDEDDMR FDKEKDKADY
510 520 530 540 550
RKDQKFADHM RDQDTGGKSD FSRKKTISEQ RRFLPVFASR QELLNVIREN
560 570 580 590 600
SVIIIVGETG SGKTTQLTQY LHEDGYSKRG MIGCTQPRRV AAMSVAKRVS
610 620 630 640 650
DEMDTQLGED VGYAIRFEDC TSERTVIKYM TDGILLRESL RDPELDSYSA
660 670 680 690 700
IIMDEAHERS LSTDVLFGLL REIVARRHDL KLIVTSATMD SSKFATFFGN
710 720 730 740 750
VPTFTIPGRT FPVDVMFSKN TCEDYVESAV KQALQVHLTP NEGDMLIFMP
760 770 780 790 800
GQEDIEVTCE VLEERLAEID NAPALSILPI YSQLPSDLQA KIFQKSSDGL
810 820 830 840 850
RKCVVATNIA ETSLTVDGII YVIDSGYCKL KVYNPRIGMD ALQIYPISQA
860 870 880 890 900
NANQRSGRAG RTGPGQAYRL YTQRQYKDEL LALTVPEIQR TNLANTVLLL
910 920 930 940 950
KSLGVVDLLQ FHFMDPPPQD NILNSLYQLW ILGALDHTGA LTTLGRQMAE
960 970 980 990 1000
FPLDPPQCQM LIVACRMGCS AEVLIIVSML SVPSIFYRPK GREDEADGVR
1010 1020 1030 1040 1050
EKFQRPESDH LTYLNVYQQW RQNNYSSTWC NEHFIHIKAM RKVREVRQQL
1060 1070 1080 1090 1100
KDIMTQQNLS VISCGIDWDI VRKCICSAYF YQAARLKGIG EYVNLRTGMP
1110 1120 1130 1140 1150
CHLHPTSALY GLGTTPDYVV YHELIMTAKE YMQCATAVDG YWLAELGPMF
1160 1170 1180 1190 1200
FSVKESGRSG REKKKQAAEH LKEMEEQMLK AQHEMEERKQ QAAEREEQLA
1210 1220
TKQEIATPGN ATPRRTPARI GL
Length:1,222
Mass (Da):139,581
Last modified:October 1, 2002 - v2
Checksum:i2E0B30A3364C1FDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF48351.2.
AY058553 mRNA. Translation: AAL13782.1.
RefSeqiNP_572947.1. NM_132719.3.
UniGeneiDm.4249.

Genome annotation databases

EnsemblMetazoaiFBtr0073900; FBpp0073717; FBgn0026713.
GeneIDi32373.
KEGGidme:Dmel_CG32604.
UCSCiCG32604-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiQ9VY54_DROME
AccessioniPrimary (citable) accession number: Q9VY54
Secondary accession number(s): Q95TT2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: August 30, 2017
This is version 152 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported